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Revision as of 16:47, 2 May 2013

Nephrotic Syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Nephrotic syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

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CT Scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

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Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Primary Causes

Primary causes of nephrotic syndrome are usually described by the histology, i.e. minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and membranous nephropathy (MN).

They are considered to be "diagnoses of exclusion", i.e. they are diagnosed only after secondary causes have been excluded.

Secondary Causes

Secondary causes of nephrotic syndrome have the same histologic patterns as the primary causes, though may exhibit some differences suggesting a secondary cause.

They are usually described by the underlying cause.

Secondary Causes by Histologic Pattern

Membranous nephropathy (MN)[1]

Focal segmental glomerulosclerosis (FSGS)[1]

Minimal change disease (MCD)[1]

GN with Nephrotic Syndrome

Acute Glomerulonenephritis

Secondary

Miscellaneous

References

  1. 1.0 1.1 1.2 Fogo AB, Bruijn JA. Cohen AH, Colvin RB, Jennette JC. Fundamentals of Renal Pathology. Springer. ISBN 978-0387-31126-5.

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