Multiple endocrine neoplasia type 1 physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Common physical examination findings of multiple endocrine neoplasia type 1 include rash, shortened QT interval, and clonus.

Physical Examination

Appearance of the Patient

• Appearance of the patients differ depending on the type of tumor and can be obese, thin or cachectic

Vitals

Temperature

• A fever is often present

Pulse

Rate

• Tachycardia may be present

Rhythm

• The pulse is regular

Respiratory Rate

• Tachypnea may be present

Skin

• Lesions may be present
• Rash may be present

Eyes

• Nystagmus may be present
• Extra-ocular movements may be abnormal

Ears

• Hearing acuity may be reduced
• Weber test may be positive
• Rinne test may be positive

Neck

• Jugular venous pressure may be elevated
• Lymph nodes may be present

Heart

• Shortened QT interval

Abdomen

• Abdominal tenderness may be present
• An acute abdomen may be present
• An abdominal mass may be present

Extremities

• Clubbing may be present
• Cyanosis may be present
• Edema may be present

Neurologic

• Mental status may be altered
• Clonus may be present