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{{Idiopathic interstitial pneumonia}}
{{Idiopathic interstitial pneumonia}}
{{CMG}}
{{CMG}}; {{AE}} {{AZ}}; {{Chetan}}
 
{{SK}} IIP


==[[Idiopathic interstitial pneumonia overview|Overview]]==
==[[Idiopathic interstitial pneumonia overview|Overview]]==
The idiopathic interstitial pneumonias are a broad range of interstitial lung diseases of unknown etiology characterized by expansion of the interstitial compartment initially by inflammatory cells ending by fibrosis due to fibroblasts proliferation and subsequent collagen deposition. It generally manifests non specifically as breathlessness and/or cough and characterized by bilateral abnormal opacities of various types on conventional chest radiographs or computed tomographic (CT) scans.


==[[Idiopathic interstitial pneumonia historical perspective|Historical Perspective]]==
==[[Idiopathic interstitial pneumonia historical perspective|Historical Perspective]]==
Averill Liebow published a paper in 1975 about definition and classification of interstitial pneumonias in human pathology. His classification was based on histological morphology in different types of idiopathic interstitial pneumonias. Usual interstitial pneumonia (UIP) and desquamative interstitial pneumonia (DIP) have persisted as important histologic groups. However others of his classification as bronchiolitis obliterans with classical interstitial pneumonia (BIP) and giant cell interstitial pneumonia (GIP) have disappeared from subsequent classification. Liebow emphasized that it was histological patterns rather than distinctive diagnostic entities, that could occur in a variety of clinical contexts. Regardless of the clinical context, however, he maintained that precise histological classification of interstitial pneumonias provides clues to etiology, pathogenesis, natural history, and prognosis. In other words, although individual histological variations do not offer distinguished diagnostic entities, However each significantly limits the differential diagnosis and can predict treatment response and outcome.


==[[Idiopathic interstitial pneumonia classification|Classification]]==
==[[Idiopathic interstitial pneumonia classification|Classification]]==
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==[[Idiopathic interstitial pneumonia causes|Causes]]==
==[[Idiopathic interstitial pneumonia causes|Causes]]==


==[[Idiopathic interstitial pneumonia differential diagnosis|Differentiating Idiopathic interstitial pneumonia from other Diseases]]==
==[[Idiopathic interstitial pneumonia differential diagnosis|Differential diagnosis]]==


==[[Idiopathic interstitial pneumonia epidemiology and demographics|Epidemiology and Demographics]]==
==[[Idiopathic interstitial pneumonia epidemiology and demographics|Epidemiology and Demographics]]==
The true incidence is unknown. UIP is the most common (50%-60%) of the idiopathic interstitial pneumonia, then NSIP 14%-36%, then DIP/RB-ILD (10%-17%) and AIP (0%-2%)<ref name="Collard-2003">{{Cite journal | last1 = Collard | first1 = HR. | last2 = King | first2 = TE. | title = Demystifying idiopathic interstitial pneumonia. | journal = Arch Intern Med | volume = 163 | issue = 1 | pages = 17-29 | month = Jan | year = 2003 | doi = | PMID = 12523913 }}</ref>


==[[Idiopathic interstitial pneumonia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Idiopathic interstitial pneumonia natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Idiopathic interstitial pneumonia history and symptoms| History and Symptoms]] | [[Idiopathic interstitial pneumonia physical examination | Physical Examination]] | [[Idiopathic interstitial pneumonia laboratory findings|Laboratory Findings]] |[[Idiopathic interstitial pneumonia CT|CT]] | [[Idiopathic interstitial pneumonia other imaging findings|Other Imaging Findings]] | [[Idiopathic interstitial pneumonia other diagnostic studies|Other Diagnostic Studies]]
[[Idiopathic interstitial pneumonia Diagnostic criteria| Diagnostic Criteria]] | [[Idiopathic interstitial pneumonia history and symptoms| History and Symptoms]] | [[Idiopathic interstitial pneumonia physical examination | Physical Examination]] | [[Idiopathic interstitial pneumonia laboratory findings|Laboratory Findings]] |[[Idiopathic interstitial pneumonia CT|CT]] | [[Idiopathic interstitial pneumonia other imaging findings|Other Imaging Findings]] | [[Idiopathic interstitial pneumonia other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
[[Idiopathic interstitial pneumonia medical therapy|Medical Therapy]] | [[Idiopathic interstitial pneumonia surgery|Surgery]] | [[Idiopathic interstitial pneumonia primary prevention|Primary Prevention]] | [[Idiopathic interstitial pneumonia secondary prevention|Secondary Prevention]] | [[Idiopathic interstitial pneumonia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Idiopathic interstitial pneumonia future or investigational therapies|Future or Investigational Therapies]]
[[Idiopathic interstitial pneumonia medical therapy|Medical Therapy]] | [[Idiopathic interstitial pneumonia surgery|Surgery]] | [[Idiopathic interstitial pneumonia primary prevention|Primary Prevention]] | [[Idiopathic interstitial pneumonia secondary prevention|Secondary Prevention]] | [[Idiopathic interstitial pneumonia cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Idiopathic interstitial pneumonia future or investigational therapies|Future or Investigational Therapies]]


==Case Studies==
==[[Idiopathic interstitial pneumonia case studies|Case studies]]==
[[Idiopathic interstitial pneumonia case study one|Case#1]]
[[Idiopathic interstitial pneumonia case study one|Case#1]]
==Related Chapters==
==References==
{{Reflist|2}}


[[Category:Disease]]
[[Category:Disease]]

Latest revision as of 18:56, 20 November 2013

Idiopathic Interstitial Pneumonia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Idiopathic interstitial pneumonia from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

CT

Endoscopy

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]; Chetan Lokhande, M.B.B.S [3]

Synonyms and keywords: IIP

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differential diagnosis

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | History and Symptoms | Physical Examination | Laboratory Findings |CT | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case studies

Case#1


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