Hypogonadism causes: Difference between revisions
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{{CMG}} {{AE}} {{ADI}} {{LRO}} | {{CMG}} {{AE}} {{ADI}} {{LRO}} | ||
==Overview== | ==Overview== | ||
Hypogonadism is commonly caused by [[congenital]] | Hypogonadism is commonly caused by [[congenital]], acquired [[genetic]] and [[endocrinology|endocrinological]] conditions. Life threatening causes may include malignancies and must take in to consideration during patient approach.<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref><ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref> | ||
==Causes | ==Causes == | ||
<div style="-webkit-user-select: none;"> | <div style="-webkit-user-select: none;"> | ||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. The following diseases are life threatening causes of hypogonadism: | |||
*[[Astrocytoma]] | *[[Astrocytoma]] | ||
*[[Chronic renal failure]] | *[[Chronic renal failure]] | ||
*[[Papillary renal cell | *[[Renal cell carcinoma|Papillary renal cell carcinoma]] | ||
* | *Postinfectious lesions of the [[CNS|central nervous system (CNS)]] | ||
* | *Ureter cancer | ||
* | *Urinary system cancer | ||
*[[Wilms tumor ]] | *[[Wilms tumor ]] | ||
*[[Infective endocarditis]] | *[[Infective endocarditis]] | ||
| Line 28: | Line 29: | ||
*[[Radiation therapy]] | *[[Radiation therapy]] | ||
*[[Sertoli-cell]]-only syndrome | *[[Sertoli-cell]]-only syndrome | ||
*Testicular biosynthetic defects | *[[Testicular]] biosynthetic defects | ||
* Autoimmune oophoritis | * [[Autoimmune]] [[oophoritis]] | ||
* Chemotherapy | * [[Chemotherapy]] | ||
* Familial and sporadic XX gonadal dysgenesis and its variants | * Familial and sporadic XX gonadal [[dysgenesis]] and its variants | ||
* Familial and sporadic XY gonadal dysgenesis and its variants | * Familial and sporadic XY gonadal dysgenesis and its variants | ||
* [[FSH]] beta subunit mutation (follicle stimulating hormone) | * [[FSH]] beta subunit mutation (follicle stimulating hormone) | ||
* [[FSH]] receptor mutation | * [[FSH]] receptor mutation | ||
* Galactosemia | * [[Galactosemia]] | ||
* Glycoprotein syndrome type 1 | * [[Glycoprotein]] syndrome type 1 | ||
* LH (luteinizing hormone) beta subunit mutation | * LH (luteinizing hormone) beta subunit mutation | ||
* LH/[[Ddx:Human Chorionic Gonadotropin|human chorionic gonadotropin]] resistance | * LH/[[Ddx:Human Chorionic Gonadotropin|human chorionic gonadotropin]] resistance | ||
| Line 44: | Line 45: | ||
* [[Polycystic ovarian disease]] | * [[Polycystic ovarian disease]] | ||
* [[Radiation therapy]] | * [[Radiation therapy]] | ||
* Resistant ovary | * Resistant [[ovary]] | ||
* [[Turner Syndrome]] | * [[Turner Syndrome]] | ||
* [[Astrocytoma]] | * [[Astrocytoma]] | ||
| Line 50: | Line 51: | ||
* Congenital adrenal hypoplasia | * Congenital adrenal hypoplasia | ||
* Congenital hypogonadotropic hypogonadism | * Congenital hypogonadotropic hypogonadism | ||
* Craniofacial anomalies | * [[Craniofacial]] anomalies | ||
* [[Craniopharyngioma]] | * [[Craniopharyngioma]] | ||
* Exercise-induced amenorrhea | * Exercise-induced amenorrhea | ||
| Line 74: | Line 75: | ||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
{|style="width:80%; height:100px" border="1" | {| style="width:80%; height:100px" border="1" | ||
| | | style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | ||
| | | style="width:75%" bgcolor="Beige" ; border="1" | [[Alström syndrome]], [[Amyloidosis]], [[Cardiofaciocutaneous syndrome]], [[Vascular abnormalities of the cns]] | ||
|- | |- | ||
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning''' | | bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | ||
|bgcolor="Beige"| [[Alcohol]], [[Alkylating agents]], [[Cytotoxic therapeutic agents]], [[Environmental toxins]], [[Ethanol]], [[Toxins]] | | bgcolor="Beige" | [[Alcohol]], [[Alkylating agents]], [[Cytotoxic therapeutic agents]], [[Environmental toxins]], [[Ethanol]], [[Toxins]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dental''' | | '''Dental''' | ||
|bgcolor="Beige"| [[Jaffe-campanacci syndrome]], [[Lepromatous leprosy]] | | bgcolor="Beige" | [[Jaffe-campanacci syndrome]], [[Lepromatous leprosy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Drug Side Effect''' | | '''Drug Side Effect''' | ||
|bgcolor="Beige"| [[Antiandrogens]], [[Ketoconazole]], [[Marijuana use]], [[Opioids]] | | bgcolor="Beige" | [[Antiandrogens]], [[Ketoconazole]], [[Marijuana use]], [[Opioids]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Ear Nose Throat''' | | '''Ear Nose Throat''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Endocrine''' | | '''Endocrine''' | ||
|bgcolor="Beige"| [[Adiposogenital dystrophy]], [[Adrenal hypoplasia]], [[Autoimmune polyendocrine syndrome type 2]], [[Combined pituitary hormone deficiency ]], [[Disorders of androgen synthesis]], [[Functional gonadotropin deficiency]], [[Glucocorticoids]], [[Glycoprotein syndrome type 1]], [[Gonadal dysgenesis ]], [[Growth hormone secreting pituitary adenoma]], [[Hyperprolactinemia]], [[Hypogonadic hypogonadism]], [[Hypopituitarism]], [[Hypothalamic glioma]], [[Panhypopituitarism]], [[Pituitary tumor]], [[Poems syndrome]], [[Polycystic ovarian disease]], [[Proprotein convertase 1/3 deficiency]], [[Pseudohypoparathyroidism type 1a]], [[Swyer's syndrome]], [[Testicular biosynthetic defects]] | | bgcolor="Beige" | [[Adiposogenital dystrophy]], [[Adrenal hypoplasia]], [[Autoimmune polyendocrine syndrome type 2]], [[Combined pituitary hormone deficiency ]] , [[Disorders of androgen synthesis]], [[Functional gonadotropin deficiency]], [[Glucocorticoids]], [[Glycoprotein syndrome type 1]], [[Gonadal dysgenesis ]] , [[Growth hormone secreting pituitary adenoma]], [[Hyperprolactinemia]], [[Hypogonadic hypogonadism]], [[Hypopituitarism]], [[Hypothalamic glioma]], [[Panhypopituitarism]], [[Pituitary tumor]], [[Poems syndrome]], [[Polycystic ovarian disease]], [[Proprotein convertase 1/3 deficiency]], [[Pseudohypoparathyroidism type 1a]], [[Swyer's syndrome]], [[Testicular biosynthetic defects]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
|bgcolor="Beige"| [[Hepatic cirrhosis]] | | bgcolor="Beige" | [[Hepatic cirrhosis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| [[17α-hydroxylase deficiency]], [[17β-hydroxysteroid dehydrogenase iii deficiency]], [[20-lyase deficiency]], [[48, xxxy aneuploidy]], [[48, xxyy aneuploidy]], [[4h syndrome]], [[Acrocephalopolysyndactyly type 2]], [[Alström syndrome]], [[Aromatase deficiency]], [[Autoimmune oophoritis]], [[Bardet-biedl syndrome]], [[Belgian type mental retardation]], [[Blepharophimosis syndrome]], [[Borjeson-forssman-lehmann syndrome]], [[Boucher-neuhäuser syndrome]], [[Cardiofaciocutaneous syndrome]], [[Ccfdn syndrome]], [[Charge syndrome]], [[Congenital adrenal hypoplasia]], [[Craniofacial anomalies]], [[Craniopharyngioma]], [[Cryptorchidism]], [[Didmoad syndrome]], [[Dystrophia myotonica type 2]], [[Fsh receptor deficiency]], [[Fsh beta subunit mutation (follicle stimulating hormone)]], [[Fsh receptor mutation]], [[Galactose-1-phosphate uridyltransferase deficiency]], [[Galactosemia]], [[Gaucher disease]], [[Gordon holmes syndrome]], [[Hartsfield syndrome]], [[Image syndrome]], [[Isolated fsh deficiency]], [[Isolated lh deficiency]], [[Jaffe-campanacci syndrome]], [[Kallmann syndrome]], [[Klinefelter syndrome]], [[Laurence-moon syndrome]], [[Leptin deficiency]], [[Lh (luteinizing hormone) beta subunit mutation]], [[Lh receptor mutation]], [[Lh resistance]], [[Lipoid congenital adrenal hyperplasia]], [[Malouf syndrome]], [[Marinesco-sjogren-garland syndrome]], [[Martsolf syndrome]], [[Mobius syndrome]], [[Mosaicism]], [[Myotonic dystrophy]], [[Noonan syndrome]], [[Prader-willi syndrome]], [[Proprotein convertase 1/3 deficiency]], [[Resistant ovary]], [[Rud syndrome]], [[Sertoli-cell-only syndrome]], [[Turner syndrome]], [[Woodhouse-sakati syndrome]], [[X-linked mental retardation-hypotonic facies syndrome]], [[Xx gonadal dysgenesis]] | | bgcolor="Beige" | [[17α-hydroxylase deficiency]], [[17β-hydroxysteroid dehydrogenase iii deficiency]], [[20-lyase deficiency]], [[48, xxxy aneuploidy]], [[48, xxyy aneuploidy]], [[4h syndrome]], [[Acrocephalopolysyndactyly type 2]], [[Alström syndrome]], [[Aromatase deficiency]], [[Autoimmune oophoritis]], [[Bardet-biedl syndrome]], [[Belgian type mental retardation]], [[Blepharophimosis syndrome]], [[Borjeson-forssman-lehmann syndrome]], [[Boucher-neuhäuser syndrome]], [[Cardiofaciocutaneous syndrome]], [[Ccfdn syndrome]], [[Charge syndrome]], [[Congenital adrenal hypoplasia]], [[Craniofacial anomalies]], [[Craniopharyngioma]], [[Cryptorchidism]], [[Didmoad syndrome]], [[Dystrophia myotonica type 2]], [[Fsh receptor deficiency]], [[Fsh beta subunit mutation (follicle stimulating hormone)]], [[Fsh receptor mutation]], [[Galactose-1-phosphate uridyltransferase deficiency]], [[Galactosemia]], [[Gaucher disease]], [[Gordon holmes syndrome]], [[Hartsfield syndrome]], [[Image syndrome]], [[Isolated fsh deficiency]], [[Isolated lh deficiency]], [[Jaffe-campanacci syndrome]], [[Kallmann syndrome]], [[Klinefelter syndrome]], [[Laurence-moon syndrome]], [[Leptin deficiency]], [[Lh (luteinizing hormone) beta subunit mutation]], [[Lh receptor mutation]], [[Lh resistance]], [[Lipoid congenital adrenal hyperplasia]], [[Malouf syndrome]], [[Marinesco-sjogren-garland syndrome]], [[Martsolf syndrome]], [[Mobius syndrome]], [[Mosaicism]], [[Myotonic dystrophy]], [[Noonan syndrome]], [[Prader-willi syndrome]], [[Proprotein convertase 1/3 deficiency]], [[Resistant ovary]], [[Rud syndrome]], [[Sertoli-cell-only syndrome]], [[Turner syndrome]], [[Woodhouse-sakati syndrome]], [[X-linked mental retardation-hypotonic facies syndrome]], [[Xx gonadal dysgenesis]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| [[Glycoprotein syndrome type 1]], [[Hemochromatosis]], [[Langerhans histiocytosis]], [[Leukoencephalopathy ]], [[Zinc deficiency]] | | bgcolor="Beige" | [[Glycoprotein syndrome type 1]], [[Hemochromatosis]], [[Langerhans histiocytosis]], [[Leukoencephalopathy ]] , [[Zinc deficiency]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Iatrogenic''' | | '''Iatrogenic''' | ||
|bgcolor="Beige"| [[Chemotherapy]], [[Opioids]], [[Orchitis]], [[Radiation therapy]], [[Surgery]] | | bgcolor="Beige" | [[Chemotherapy]], [[Opioids]], [[Orchitis]], [[Radiation therapy]], [[Surgery]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Aids]], [[Infections]], [[Mumps]] | | bgcolor="Beige" | [[Aids]], [[Infections]], [[Mumps]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal/Orthopedic''' | | '''Musculoskeletal/Orthopedic''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| [[Astrocytoma]], [[Belgian type mental retardation]], [[Craniopharyngioma]], [[Gordon holmes syndrome]], [[Poems syndrome]], [[Postinfectious lesions of the central nervous system (cns)]], [[Vascular abnormalities of the cns]] | | bgcolor="Beige" | [[Astrocytoma]], [[Belgian type mental retardation]], [[Craniopharyngioma]], [[Gordon holmes syndrome]], [[Poems syndrome]], [[Postinfectious lesions of the central nervous system (cns)]], [[Vascular abnormalities of the cns]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"| [[Zinc deficiency]] | | bgcolor="Beige" | [[Zinc deficiency]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Obstetric/Gynecologic''' | | '''Obstetric/Gynecologic''' | ||
|bgcolor="Beige"| [[Exercise-induced amenorrhea]], [[Ovarian resistance syndrome]], [[Ovarian torsion]], [[Polycystic ovarian disease]], [[Premature ovarian failure]], [[Premature menopause]], [[Resistant ovary]], [[Rud syndrome]], [[Suramin]], [[Swyer's syndrome]] | | bgcolor="Beige" | [[Exercise-induced amenorrhea]], [[Ovarian resistance syndrome]], [[Ovarian torsion]], [[Polycystic ovarian disease]], [[Premature ovarian failure]], [[Premature menopause]], [[Resistant ovary]], [[Rud syndrome]], [[Suramin]], [[Swyer's syndrome]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| [[Astrocytoma]], [[Germinoma]], [[Growth hormone secreting pituitary adenoma]], [[Hypothalamic glioma]], [[Langerhans histiocytosis]], [[Optic glioma]], [[Other germ cell tumors]], [[Pituitary tumor]] | | bgcolor="Beige" | [[Astrocytoma]], [[Germinoma]], [[Growth hormone secreting pituitary adenoma]], [[Hypothalamic glioma]], [[Langerhans histiocytosis]], [[Optic glioma]], [[Other germ cell tumors]], [[Pituitary tumor]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Ophthalmologic''' | | '''Ophthalmologic''' | ||
|bgcolor="Beige"| [[Optic glioma]] | | bgcolor="Beige" | [[Optic glioma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Overdose/Toxicity''' | | '''Overdose/Toxicity''' | ||
|bgcolor="Beige"| [[Alcohol]] | | bgcolor="Beige" | [[Alcohol]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Psychiatric''' | | '''Psychiatric''' | ||
|bgcolor="Beige"| [[Anorexia nervosa]] | | bgcolor="Beige" | [[Anorexia nervosa]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Pulmonary''' | | '''Pulmonary''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Renal/Electrolyte''' | | '''Renal/Electrolyte''' | ||
|bgcolor="Beige"| [[Chronic renal failure]], [[Renal failure]] | | bgcolor="Beige" | [[Chronic renal failure]], [[Renal failure]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Rheumatology/Immunology/Allergy''' | | '''Rheumatology/Immunology/Allergy''' | ||
|bgcolor="Beige"| [[Amyloidosis]], [[Autoimmune damage]], [[Autoimmunity]], [[Chronic systemic illnesses]], [[Lepromatous leprosy]] | | bgcolor="Beige" | [[Amyloidosis]], [[Autoimmune damage]], [[Autoimmunity]], [[Chronic systemic illnesses]], [[Lepromatous leprosy]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Sexual''' | | '''Sexual''' | ||
|bgcolor="Beige"| [[Aids]], [[Epididymo-orchitis]], [[Germinoma]], [[Orchidectomy]], [[Suramin]] | | bgcolor="Beige" | [[Aids]], [[Epididymo-orchitis]], [[Germinoma]], [[Orchidectomy]], [[Suramin]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| [[Head trauma]], [[Hepatic cirrhosis]], [[Ovarian torsion]], [[Testicular torsion]], [[Trauma]] | | bgcolor="Beige" | [[Head trauma]], [[Hepatic cirrhosis]], [[Ovarian torsion]], [[Testicular torsion]], [[Trauma]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Urologic''' | | '''Urologic''' | ||
|bgcolor="Beige"| [[Anorchia]], [[Anorchidism]], [[Congenital hypogonadotropic hypogonadism]], [[Cryptorchidism]], [[Disorders of androgen synthesis]], [[Epididymo-orchitis]], [[Gonadal dysgenesis ]], [[Hypogonadic hypogonadism]], [[Orchitis]], [[Testicular torsion]], [[Varicocele]] | | bgcolor="Beige" | [[Anorchia]], [[Anorchidism]], [[Congenital hypogonadotropic hypogonadism]], [[Cryptorchidism]], [[Disorders of androgen synthesis]], [[Epididymo-orchitis]], [[Gonadal dysgenesis ]] , [[Hypogonadic hypogonadism]], [[Orchitis]], [[Testicular torsion]], [[Varicocele]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
|bgcolor="Beige"| No underlying causes | | bgcolor="Beige" | No underlying causes | ||
|- | |- | ||
|} | |} | ||
===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
{{columns-list | {{columns-list| | ||
*[[17α-hydroxylase deficiency]] | *[[17α-hydroxylase deficiency]] | ||
*[[17β-hydroxysteroid dehydrogenase iii deficiency]] | *[[17β-hydroxysteroid dehydrogenase iii deficiency]] | ||
| Line 485: | Line 486: | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
Latest revision as of 21:20, 10 January 2020
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Hypogonadism Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hypogonadism causes On the Web |
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American Roentgen Ray Society Images of Hypogonadism causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.
Overview
Hypogonadism is commonly caused by congenital, acquired genetic and endocrinological conditions. Life threatening causes may include malignancies and must take in to consideration during patient approach.[1][2]
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. The following diseases are life threatening causes of hypogonadism:
- Astrocytoma
- Chronic renal failure
- Papillary renal cell carcinoma
- Postinfectious lesions of the central nervous system (CNS)
- Ureter cancer
- Urinary system cancer
- Wilms tumor
- Infective endocarditis
Common Causes
- Anorchidism
- Chemotherapy
- Cryptorchidism
- FSH beta subunit mutation (follicle stimulating hormone)
- FSH receptor mutation
- Klinefelter Syndrome
- LH (luteinizing hormone) beta subunit mutation
- LH receptor mutation
- LH resistance
- Radiation therapy
- Sertoli-cell-only syndrome
- Testicular biosynthetic defects
- Autoimmune oophoritis
- Chemotherapy
- Familial and sporadic XX gonadal dysgenesis and its variants
- Familial and sporadic XY gonadal dysgenesis and its variants
- FSH beta subunit mutation (follicle stimulating hormone)
- FSH receptor mutation
- Galactosemia
- Glycoprotein syndrome type 1
- LH (luteinizing hormone) beta subunit mutation
- LH/human chorionic gonadotropin resistance
- LH receptor mutation
- Noonan Syndrome
- Premature menopause
- Polycystic ovarian disease
- Radiation therapy
- Resistant ovary
- Turner Syndrome
- Astrocytoma
- Bardet-Biedl Syndrome
- Congenital adrenal hypoplasia
- Congenital hypogonadotropic hypogonadism
- Craniofacial anomalies
- Craniopharyngioma
- Exercise-induced amenorrhea
- Functional gonadotropin deficiency
- Gaucher Disease
- Germinoma
- Head trauma
- Hyperprolactinemia
- Hypothalamic glioma
- Isolated FSH deficiency
- Isolated LH deficiency
- Kallmann Syndrome
- Langerhans histiocytosis
- Laurence-Moon Syndrome
- Marijuana use
- Optic glioma
- Other germ cell tumors
- Pituitary tumor
- Postinfectious lesions of the central nervous system (CNS)
- Prader-Willi Syndrome
- Radiation therapy
- Vascular abnormalities of the CNS
Causes by Organ System
Causes in Alphabetical Order
- 17α-hydroxylase deficiency
- 17β-hydroxysteroid dehydrogenase iii deficiency
- 20-lyase deficiency
- 48, xxxy aneuploidy
- 48, xxyy aneuploidy
- 4h syndrome
- Acrocephalopolysyndactyly type 2
- Adiposogenital dystrophy
- Adrenal hypoplasia
- Aids
- Alcohol
- Alkylating agents
- Alström syndrome
- Amyloidosis
- Anorchia
- Anorchidism
- Anorexia nervosa
- Antiandrogens
- Aromatase deficiency
- Astrocytoma
- Autoimmune damage
- Autoimmune oophoritis
- Autoimmune polyendocrine syndrome type 2
- Autoimmunity
- Bardet-biedl syndrome
- Belgian type mental retardation
- Blepharophimosis syndrome
- Borjeson-forssman-lehmann syndrome
- Boucher-neuhäuser syndrome
- Cardiofaciocutaneous syndrome
- Ccfdn syndrome
- Charge syndrome
- Chemotherapy
- Chronic renal failure
- Chronic systemic illnesses
- Combined pituitary hormone deficiency
- Congenital adrenal hypoplasia
- Congenital hypogonadotropic hypogonadism
- Craniofacial anomalies
- Craniopharyngioma
- Cryptorchism
- Cytotoxic therapeutic agents
- Didmoad syndrome
- Disorders of androgen synthesis
- Dystrophia myotonica type 2
- Environmental toxins
- Epididymo-orchitis
- Ethanol
- Exercise-induced amenorrhea
- Fsh receptor deficiency
- Fsh beta subunit mutation (follicle stimulating hormone)
- Fsh receptor mutation
- Functional gonadotropin deficiency
- Galactose-1-phosphate uridyltransferase deficiency
- Galactosemia
- Gaucher disease
- Germinoma
- Glucocorticoids
- Glycoprotein syndrome type 1
- Gonadal dysgenesis
- Gordon holmes syndrome
- Growth hormone secreting pituitary adenoma
- Hartsfield syndrome
- Head trauma
- Hemochromatosis
- Hepatic cirrhosis
- Hyperprolactinemia
- Hypogonadic hypogonadism
- Hypogonadotrophic hypogonadism
- Hypopituitarism
- Hypothalamic glioma
- Idiopathic
- Image syndrome
- Infections
- Isolated fsh deficiency
- Isolated lh deficiency
- Jaffe-campanacci syndrome
- Kallmann syndrome
- Ketoconazole
- Klinefelter syndrome
- Langerhans histiocytosis
- Laurence-moon syndrome
- Lepromatous leprosy
- Leptin deficiency
- Leukoencephalopathy
- Lh (luteinizing hormone) beta subunit mutation
- Lh receptor mutation
- Lh resistance
- Lipoid congenital adrenal hyperplasia
- Malouf syndrome
- Marijuana use
- Marinesco-sjogren-garland syndrome
- Martsolf syndrome
- Mobius syndrome
- Mosaicism
- Mumps
- Myotonic dystrophy
- Noonan syndrome
- Opioids
- Optic glioma
- Orchidectomy
- Orchitis
- Other germ cell tumors
- Ovarian resistance syndrome
- Ovarian torsion
- Panhypopituitarism
- Pituitary tumor
- Poems syndrome
- Polycystic ovarian disease
- Postinfectious lesions of the central nervous system (cns)
- Prader-willi syndrome
- Premature ovarian failure
- Premature menopause
- Proprotein convertase 1/3 deficiency
- Pseudohypoparathyroidism type 1a
- Radiation therapy
- Radiotherapy
- Renal failure
- Resistant ovary
- Rud syndrome
- Sertoli-cell-only syndrome
- Suramin
- Surgery
- Swyer's syndrome
- Testicular biosynthetic defects
- Testicular torsion
- Toxins
- Trauma
- Turner syndrome
- Varicocele
- Vascular abnormalities of the cns
- Woodhouse-sakati syndrome
- X-linked mental retardation-hypotonic facies syndrome
- Xx gonadal dysgenesis
- Zinc deficiency
- Hemophilia
- Henoch-schonlein purpura
- Hepatitis a
- Hepatitis b
- Hepatitis c
- Hepatorenal tyrosinemia
- Hereditary hemorrhagic telangiectasia
- Hereditary leiomyomatosis
- Herns syndrome
- Honeymoon bladder
- Hypercalciuria
- Hypertension
- Hypocomplementemic urticarial vasculitis
- Idarubicin
- Iga nephropathy
- Immune thrombocytopenic purpura
- Indandione rodenticide poisoning
- Infective endocarditis
- Interstitial nephritis
- Jaundice
- Juniper tar poisoning
- Kidney cancer
- Kidney stones
- Klerat rodenticide poisoning
- Lactate dehydrogenase deficiency
- Lecithin-cholesterol acyltransferase deficiency
- Leiomyomatosis of esophagus
- Leucinosis
- Leukocytoclastic angiitis
- Liver cancer
- Machupo virus
- Malaria
- Malignant rhabdoid tumors
- Maple syrup urine disease
- Matikus rodenticide poisoning
- Medullary sponge kidney
- Meier-blumberg-imahorn syndrome
- Melanoma
- Membranous nephropathy
- Mepacrine
- Methaemoglobinaemia
- Metronidazole
- Milky urine
- Mitoxantrone
- Monosodium methanarsenate
- Mouser rodenticide poisoninge
- Myoglobinuria
- Nail-patella syndrome
- Naked brimcap poisoning
- Naphthalene
- Nefopam
- Neoplastic porphyria tarda
- Nephritis
- Nephrocalcinosis
- Nephropathy
- Nephrosis
- Nitrates
- Norum disease
- Obstructive jaundice
- Oncocytoma
- Oral contraceptives
- Orchitis
- Oxalosis
- Oxamniquine
- Papillary renal cell carcinoma
- Paragonimiases
- Parkinson's disease
- Pelvic fracture
- Pelvic lipomatosis
- Penis cancer
- Penis conditions
- Penis tourniquet syndrome
- Pennyroyal oil
- Peppermint oil
- Petroleum distillates
- Phenazopyridine
- Phenol
- Phenolphthalein
- Phensuximide
- Phosphine
- Phyllodes tumor of the prostate
- Pierson syndrome
- Pindone rodenticide poisoning
- Pixantrone
- Polycystic kidney disease
- Porphyria
- Precalicial canalicular ectasia
- Prostate cancer
- Prostatic abscess
- Prostatitis
- Pyelonephritis
- Quebec platelet disorder
- Ratak plus rodenticide poisoning
- Reflux nephropathy
- Reiter’s syndrome
- Renal abscess
- Renal cancer
- Renal colic
- Renal failure
- Renal hypertension
- Renal mucormycosis
- Renal nutcracker syndrome
- Renal zygmycosis
- Renovascular hypertension
- Rhabdoid tumor
- Rhabdomyolysis
- Rhubarb
- Rifabutin
- Rifampicin
- Rodend rodenticide poisoning
- Rue
- Salcedo syndrome
- Sarcoma botryoides
- Schistosomiasis
- Senna
- Southworth symptom complex
- Spirochetes disease
- Stones
- Stuart factor deficiency
- Sulphasalazine
- Talon rodenticide poisoning
- Thalassemia
- Thrombasthenia
- Thrombocytopathy
- Thrombocytopenia
- Thrombocytopenic purpura
- Torulopsis
- Toxic epidermal necrolysis
- Toxic mushrooms
- Transitional cell carcinoma
- Trichosporin infection
- Tuberculosis
- Turpentine oil
- Urachal cancer
- Urachal cyst
- Urban schosser spohn syndrome
- Ureter cancer
- Urethral cancer
- Urinary disorders
- Urinary stones
- Urinary system cancer
- Urinary tract infections
- Urod-related porphyria cutanea tarda
- Vasculitis hypersensitivity
- Vasculitis
- Volak rodenticide poisoning
- Volid rodenticide poisoning
- Wegener's granulomatosis
- Weil syndrome
- Wilms tumor
- Wilson's disease
- Xanthic urolithiasis
- Xanthine oxydase deficiency
- Xanthinuria
- Yellow fever