Hospital-acquired pneumonia prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Prevention

Sterilization or Disinfection and Maintenance of Equipment and Devices

Preventive Measures Description
General measures
  • Thoroughly clean all equipment and devices to be sterilized or disinfected.
  • Whenever possible, use steam sterilization (by autoclaving) or high-level disinfection by wet heat pasteurization at >158 F (>70°C) for 30 minutes for reprocessing semicritical equipment or devices
  • Use sterile water for rinsing reusable semicritical respiratory equipment and devices when rinsing is needed after they have been chemically disinfected.
  • Do not routinely sterilize or disinfect the internal machinery of mechanical ventilators
  • Wear gloves to perform the previous procedure and/or when handling the fluid
  • Use sterile (not distilled, nonsterile) water to fill bubbling humidifiers
Mechanical ventilators
  • Do not routinely sterilize or disinfect the internal machinery of mechanical ventilators
Breathing circuits with humidifiers
  • Do not change routinely, on the basis of duration of use, the breathing circuit (i.e., ventilator tubing and exhalation valve and the attached humidifier) that is in use on an individual patient. Change the circuit when it is visibly soiled or mechanically malfunctioning
  • Periodically drain and discard any condensate that collects in the tubing of a mechanical ventilator, taking precautions not to allow condensate to drain toward the patient
Ventilator breathing circuits with heat-and-moisture exchangers (HME)
  • No recommendation can be made for the preferential use of either HMEs or heated humidifiers to prevent pneumonia in patients receiving mechanically assisted ventilation
  • Change an HME that is in use on a patient when it malfunctions mechanically or becomes visibly soiled
Small-volume medication nebulizers: in-line and hand-held nebulizers
  • Between treatments on the same patient clean, disinfect, rinse with sterile water (if rinsing is needed), and dry small-volume in-line or hand-held medication nebulizers
  • Use only sterile fluid for nebulization, and dispense the fluid into the nebulizer aseptically
Other devices used in association with respiratory therapy
  • Respirometer and ventilator thermometer: between their uses on different patients, sterilize or subject to high-level disinfection portable respirometers and ventilator thermometers
  • Resuscitation bags: between their uses on different patients, sterilize or subject to high-level disinfection reusable hand-powered resuscitation bags
Table adapted from CDC[1][2]

Prevention of Person-to-Person Transmission of Bacteria

References

  1. "CDC Guidelines for Preventing Health-Care--Associated Pneumonia, 2003".
  2. Coffin, Susan E.; Klompas, Michael; Classen, David; Arias, Kathleen M.; Podgorny, Kelly; Anderson, Deverick J.; Burstin, Helen; Calfee, David P.; Dubberke, Erik R.; Fraser, Victoria; Gerding, Dale N.; Griffin, Frances A.; Gross, Peter; Kaye, Keith S.; Lo, Evelyn; Marschall, Jonas; Mermel, Leonard A.; Nicolle, Lindsay; Pegues, David A.; Perl, Trish M.; Saint, Sanjay; Salgado, Cassandra D.; Weinstein, Robert A.; Wise, Robert; Yokoe, Deborah S. (2008). "Strategies to Prevent Ventilator‐Associated Pneumonia in Acute Care Hospitals •". Infection Control and Hospital Epidemiology. 29 (S1): S31–S40. doi:10.1086/591062. ISSN 0899-823X.

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