HLA-DO: Difference between revisions
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{{infobox protein | |||
| name = [[HLA-DOA|major histocompatibility complex, class II, DO alpha]] | |||
| caption = | |||
| image = | |||
| width = | |||
| HGNCid = 4936 | |||
| Symbol = [[HLA-DOA]] | |||
| AltSymbols = HLA-DZA, HLA-DNA | |||
| EntrezGene = 3111 | |||
| OMIM = 142930 | |||
| RefSeq = NM_002119 | |||
| UniProt = Q9TQD3 | |||
| PDB = | |||
| ECnumber = | |||
| Chromosome = 6 | |||
| Arm = p | |||
| Band = 21.3 | |||
| LocusSupplementaryData = | |||
}} | |||
{{infobox protein | |||
| Name = [[HLA-DOB|major histocompatibility complex, class II, DO beta]] | |||
| caption = | |||
| image = | |||
| width = | |||
| HGNCid = 4937 | |||
| Symbol = [[HLA-DOB]] | |||
| AltSymbols = | |||
| EntrezGene = 3112 | |||
| OMIM = 600629 | |||
| RefSeq = NM_002120 | |||
| UniProt = P13765 | |||
| PDB = | |||
| ECnumber = | |||
| Chromosome = 6 | |||
| Arm = p | |||
| Band = 21.3 | |||
| LocusSupplementaryData = | |||
}} | |||
'''HLA-DO''' is a dimeric [[MHC class II]] [[protein]] composed of [[HLA-DOA|α-]] and [[HLA-DOB|β]]-subunits which interacts with [[HLA-DM]] in order to fine tune immunodominant epitope selection. | |||
==References== | |||
{{Sadegh-Nasseri S. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells [version 1; referees: 4 approved]. F1000Research 2016, 5(F1000 Faculty Rev):1305 (doi: 10.12688/f1000research.7664.1)}} | |||
{{Surface antigens}} | |||
a | |||
[[Category:MHC Class II]] | |||
{{ | {{immunology-stub}} | ||
Revision as of 22:05, 30 November 2016
| major histocompatibility complex, class II, DO alpha | |
|---|---|
| Identifiers | |
| Symbol | HLA-DOA |
| Alt. symbols | HLA-DZA, HLA-DNA |
| Entrez | 3111 |
| HUGO | 4936 |
| OMIM | 142930 |
| RefSeq | NM_002119 |
| UniProt | Q9TQD3 |
| Other data | |
| Locus | Chr. 6 p21.3 |
| major histocompatibility complex, class II, DO beta | |
|---|---|
| Identifiers | |
| Symbol | HLA-DOB |
| Entrez | 3112 |
| HUGO | 4937 |
| OMIM | 600629 |
| RefSeq | NM_002120 |
| UniProt | P13765 |
| Other data | |
| Locus | Chr. 6 p21.3 |
HLA-DO is a dimeric MHC class II protein composed of α- and β-subunits which interacts with HLA-DM in order to fine tune immunodominant epitope selection.
References
{{Sadegh-Nasseri S. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells [version 1; referees: 4 approved]. F1000Research 2016, 5(F1000 Faculty Rev):1305 (doi: 10.12688/f1000research.7664.1)}}
a
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