Gastrointestinal stromal tumor MRI: Difference between revisions
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{{Gastrointestinal stromal tumor}} | {{Gastrointestinal stromal tumor}} | ||
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==Overview== | ==Overview== | ||
MRI scan | [[MRI]] is more accurate and sensitive than a [[CT scan]] for delineating [[rectal]] gastrointestinal stromal tumors (GISTs). For GISTs located at other locations [[MRI]] is as sensitive as a [[CT scan]]. However, a [[biopsy]] ([[Endoscopy|endoscopic]] or [[CT]] guided) is the [[Gold standard (test)|gold standard]] in diagnosing GIST. On a T1 weighted [[Magnetic resonance imaging|MRI]], low signal [[intensity]] indicates solid component GIST whereas on a T2 weighted [[Magnetic resonance imaging|MRI]], high signal [[intensity]] indicates solid component GISTs. | ||
==MRI== | ==MRI== | ||
[[MRI]] is more accurate and sensitive than a [[CT scan]] for delineating rectal gastrointestinal stromal tumors (GISTs). For GISTs located at other locations [[MRI]] is as sensitive as a [[CT scan]].<ref name="pmid15648083">{{cite journal |vauthors=Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K, Kindblom LG |title=Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden |journal=Cancer |volume=103 |issue=4 |pages=821–9 |year=2005 |pmid=15648083 |doi=10.1002/cncr.20862 |url=}}</ref><ref name="pmid14645423">{{cite journal |vauthors=Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA |title=Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor |journal=J. Clin. Oncol. |volume=21 |issue=23 |pages=4342–9 |year=2003 |pmid=14645423 |doi=10.1200/JCO.2003.04.190 |url=}}</ref> | |||
*T1: | *[[MRI]] is more sensitive in identifying GIST associated [[hemorrhage]], [[necrosis]], surrounding structures and [[metastasis]]. | ||
* On an [[MRI]], the presence of [[hemorrhage]], [[necrosis]] and cystic change may have variable appearance: | |||
**On a T1 weighted [[Magnetic resonance imaging|MRI]]: | |||
***Low signal [[Intensity (physics)|intensity]] indicates solid component GISTs. | |||
* | ***With larger GISTs, contrast induced enhancement is present and predominantly peripheral in larger [[Lesion|lesions]] (>10 cms). | ||
**On a T2 weighted [[Magnetic resonance imaging|MRI]] | |||
*** High signal intensity indicates solid component GISTs. | |||
==References== | ==References== | ||
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Latest revision as of 03:43, 4 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
MRI is more accurate and sensitive than a CT scan for delineating rectal gastrointestinal stromal tumors (GISTs). For GISTs located at other locations MRI is as sensitive as a CT scan. However, a biopsy (endoscopic or CT guided) is the gold standard in diagnosing GIST. On a T1 weighted MRI, low signal intensity indicates solid component GIST whereas on a T2 weighted MRI, high signal intensity indicates solid component GISTs.
MRI
MRI is more accurate and sensitive than a CT scan for delineating rectal gastrointestinal stromal tumors (GISTs). For GISTs located at other locations MRI is as sensitive as a CT scan.[1][2]
- MRI is more sensitive in identifying GIST associated hemorrhage, necrosis, surrounding structures and metastasis.
- On an MRI, the presence of hemorrhage, necrosis and cystic change may have variable appearance:
References
- ↑ Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K, Kindblom LG (2005). "Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden". Cancer. 103 (4): 821–9. doi:10.1002/cncr.20862. PMID 15648083.
- ↑ Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA (2003). "Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor". J. Clin. Oncol. 21 (23): 4342–9. doi:10.1200/JCO.2003.04.190. PMID 14645423.