Gastrointestinal stromal tumor CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

A CT scan of the abdomen and pelvis is the imaging test of choice and an important tool in the diagnosis of gastrointestinal stromal tumor (GIST). CT scan can be used to determine the size, location and staging of GIST. A CT scan can accurately de-mark surrounding structures, multiple tumors and metastases. On a CT scan, a small GIST (< 5 cms) appears as homogeneous mass with clear boundaries, while a large GIST (>10cms) appears as a heterogeneous mass with irregular borders and have local or distant spread.

CT scan

A CT scan of the abdomen and pelvis is the imaging test of choice and an important tool in the diagnosis of gastrointestinal stromal tumor (GIST). However, a biopsy (endoscopic or CT guided) is the gold standard in diagnosing GIST. [1][2][3][4][5][6]

CT without contrast showing an incidental finding of a small GIST in the posterior stomach wall (arrow). ([Courtesy: By Inversitus - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=33932071])
CT scan showing a GIST located in the gastric cardia. ([Courtesy: By Jto410 (from my radiology practice) [GFDL (http://www.gnu.org/copyleft/fdl.html) or CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons])

References

  1. "Gastrointestinal stromal tumour".
  2. Tran T, Davila JA, El-Serag HB (2005). "The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000". Am. J. Gastroenterol. 100 (1): 162–8. doi:10.1111/j.1572-0241.2005.40709.x. PMID 15654796.
  3. Miettinen M, Makhlouf H, Sobin LH, Lasota J (2006). "Gastrointestinal stromal tumors of the jejunum and ileum: a clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up". Am. J. Surg. Pathol. 30 (4): 477–89. PMID 16625094.
  4. Burkill GJ, Badran M, Al-Muderis O, Meirion Thomas J, Judson IR, Fisher C, Moskovic EC (2003). "Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread". Radiology. 226 (2): 527–32. doi:10.1148/radiol.2262011880. PMID 12563150.
  5. Hersh MR, Choi J, Garrett C, Clark R (2005). "Imaging gastrointestinal stromal tumors". Cancer Control. 12 (2): 111–5. PMID 15855894.
  6. Pidhorecky I, Cheney RT, Kraybill WG, Gibbs JF (2000). "Gastrointestinal stromal tumors: current diagnosis, biologic behavior, and management". Ann. Surg. Oncol. 7 (9): 705–12. PMID 11034250.


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