Folate deficiency laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
First line investigations include the following: | |||
*Examination of peripheral blood smear : Macrocytic anemia and hypersegmented neutrophils are classically seen in folate deficiency. Anisocytosis and poikilocytosis can also be observed. | |||
*Complete Blood Count : Low hemoglobin, elevated MCV and MCH, thrombocytopenia, neutropenia. | |||
*Reticulocyte count : Low corrected reticulocyte count which indicates decreased production by the bone marrow. | |||
{| | {| | ||
|-style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| '''Reference Range''' || | | '''Reference Range''' || | ||
|-style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| '''Folic Acid in Serum/Plasma Deficiency''' || '''3.6-15 mg/dl''' | | '''Folic Acid in Serum/Plasma Deficiency''' || '''3.6-15 mg/dl''' | ||
|- style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| '''Adequate Folic Acid Supply''' || '''> 4 ug/l''' | | '''Adequate Folic Acid Supply''' || '''> 4 ug/l''' | ||
|-style="background:silver; color:black" | |- style="background:silver; color:black" | ||
| '''Erythrocyte Folic Acid''' || '''120-800 ug/l''' | | '''Erythrocyte Folic Acid''' || '''120-800 ug/l''' | ||
|} | |} | ||
Revision as of 19:48, 20 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Laboratory Findings
First line investigations include the following:
- Examination of peripheral blood smear : Macrocytic anemia and hypersegmented neutrophils are classically seen in folate deficiency. Anisocytosis and poikilocytosis can also be observed.
- Complete Blood Count : Low hemoglobin, elevated MCV and MCH, thrombocytopenia, neutropenia.
- Reticulocyte count : Low corrected reticulocyte count which indicates decreased production by the bone marrow.
| Reference Range | |
| Folic Acid in Serum/Plasma Deficiency | 3.6-15 mg/dl |
| Adequate Folic Acid Supply | > 4 ug/l |
| Erythrocyte Folic Acid | 120-800 ug/l |