Folate deficiency history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History plays an important role in folate deficiency as the signs and symptoms associated with it are subtle and non specific.[1]
History and Symptoms
History
History presents a pivotal role in determining the causative agent of the folate deficiency anemia.The patients of folate deficiency anemia may present with a positive history of:
- Pregnancy or Lactation
- Malabsorption
- Decreased dietary intake
- Chronic disease like history of chronic hemolytic anemia or Exfoliative dermatitis
- Excessive alcohol intake
- Use of certain medication like Methotrexate, Phenytoin and Sulphonamide,Trimethoprim
- history of chronic renal failure on hemodialysis
Common symptoms
- Sore tongue
- Anorexia
- Slow growth rate
- Depression
- Dementia
- premature and low birth weight infacts born to pregnant lady with folate deficiency
Less common symptoms
- Diarrhea
- Weight loss
- Nausea
- Vomiting
- Abdominal pain
References
- ↑ Green R, Datta Mitra A (2017). "Megaloblastic Anemias: Nutritional and Other Causes". Med Clin North Am. 101 (2): 297–317. doi:10.1016/j.mcna.2016.09.013. PMID 28189172.