Essential thrombocytosis epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
The incidence of | The annual incidence of essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> Although in reality, the number may be much more higher attributing to the incidental diagnosis of the condition and many go undiagnosed due to lack of routine medical care. The median age at onset is 65-70 years. Worldwide, the prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.<ref name=fm>Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015</ref> The disease shows a slight female preponderance in the elderly patients while the incidence remains the same in patients who present with ET in their 3rd decade of life.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> | ||
==Epidemiology== | ==Epidemiology== | ||
===Incidence=== | ===Incidence=== | ||
*The incidence of | *The annual incidence of essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.<ref name="pmid19636672">{{cite journal| author=Fabris F, Randi ML| title=Essential thrombocythemia: past and present. | journal=Intern Emerg Med | year= 2009 | volume= 4 | issue= 5 | pages= 381-8 | pmid=19636672 | doi=10.1007/s11739-009-0284-x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19636672 }} </ref> | ||
*In reality the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care. | *In reality the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care. | ||
===Prevalence=== | ===Prevalence=== | ||
*Worldwide, the prevalence of | *Worldwide, the prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.<ref name=fm>Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015</ref>. | ||
===Age=== | ===Age=== | ||
*Essential thrombocytosis is usually first diagnosed in the late 50's or early 60's. | *Essential thrombocytosis is usually first diagnosed in the late 50's or early 60's. | ||
*ET has a bimodal presentation in that it presents in people in their 60's | *ET has a bimodal presentation in that it presents in people in their 60's whith the other peak occurs in the 30's. | ||
*The median age at onset is 65-70 years. | *The median age at onset is 65-70 years. | ||
===Gender=== | ===Gender=== | ||
*Women in their third decade of life are more commonly affected with | *Women in their third decade of life are more commonly affected with essential thrombocytosis than men at same age. The male to female ratio is approximately 1:2.<ref name="pmid17210076">{{cite journal| author=Brière JB| title=Essential thrombocythemia. | journal=Orphanet J Rare Dis | year= 2007 | volume= 2 | issue= | pages= 3 | pmid=17210076 | doi=10.1186/1750-1172-2-3 | pmc=PMC1781427 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17210076 }} </ref> | ||
*Patients in the 6th decade of life usually have same incidence in both men and women. | *Patients who present in the 6th decade of life usually have same incidence in both men and women. | ||
==References== | ==References== | ||
Revision as of 19:45, 11 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
The annual incidence of essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.[1] Although in reality, the number may be much more higher attributing to the incidental diagnosis of the condition and many go undiagnosed due to lack of routine medical care. The median age at onset is 65-70 years. Worldwide, the prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.[2] The disease shows a slight female preponderance in the elderly patients while the incidence remains the same in patients who present with ET in their 3rd decade of life.[1]
Epidemiology
Incidence
- The annual incidence of essential thrombocytosis was estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.[1]
- In reality the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care.
Prevalence
- Worldwide, the prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.[2].
Age
- Essential thrombocytosis is usually first diagnosed in the late 50's or early 60's.
- ET has a bimodal presentation in that it presents in people in their 60's whith the other peak occurs in the 30's.
- The median age at onset is 65-70 years.
Gender
- Women in their third decade of life are more commonly affected with essential thrombocytosis than men at same age. The male to female ratio is approximately 1:2.[3]
- Patients who present in the 6th decade of life usually have same incidence in both men and women.
References
- ↑ 1.0 1.1 1.2 Fabris F, Randi ML (2009). "Essential thrombocythemia: past and present". Intern Emerg Med. 4 (5): 381–8. doi:10.1007/s11739-009-0284-x. PMID 19636672.
- ↑ 2.0 2.1 Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015
- ↑ Brière JB (2007). "Essential thrombocythemia". Orphanet J Rare Dis. 2: 3. doi:10.1186/1750-1172-2-3. PMC 1781427. PMID 17210076.