Essential thrombocytosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

The incidence of essential thrombocytosis is approximately 0.6-2.5 cases per 100,000 individuals worldwide annually.[1] The prevalence of essential thrombocytosis is about 30 for every 100,000 people worldwide.[2] The incidence of essential thrombocytosis increases with age; the median age at diagnosis is 65-70 years. Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.[3] Females are more commonly affected with essential thrombocytosis than males.[3] The female to male ratio is approximately 2 to 1.[1]

Epidemiology

Incidence

  • The annual incidence of essential thrombocytosis is estimated to be 0.6-2.5 cases per 100,000 individuals worldwide.[1]
  • In reality, the incidence may be much more higher attributing the incidental diagnosis of the condition where many go undiagnosed due to lack of routine medical care.

Prevalence

  • Worldwide, the prevalence of essential thrombocytosis is approximately 30 for every 100,000 individuals worldwide.[2].

Age

  • Patients of all age groups may develop essential thrombocytosis. However it commonly affects individuals older than 60 years of age.[3]
  • The median age at onset is 65-70 years.

Gender

  • Women in their third decade of life are more commonly affected with essential thrombocytosis than men at same age. The female to male ratio is approximately 2:1.[4]
  • Patients who present in the 6th decade of life usually have same incidence in both men and women.

References

  1. ↑ 1.0 1.1 1.2 Fabris F, Randi ML (2009). "Essential thrombocythemia: past and present". Intern Emerg Med. 4 (5): 381–8. doi:10.1007/s11739-009-0284-x. PMID 19636672.
  2. ↑ 2.0 2.1 Essential Thrombocythemia. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/essential-thrombocythemia. Accessed on October 29, 2015
  3. ↑ 3.0 3.1 3.2 Essential Thrombocythemia (ET). MPN Research foundation. http://www.mpnresearchfoundation.org/Essential-Thrombocythemia Accessed on November 15, 2015.
  4. ↑ Brière JB (2007). "Essential thrombocythemia". Orphanet J Rare Dis. 2: 3. doi:10.1186/1750-1172-2-3. PMC 1781427. PMID 17210076.


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