Erysipelas laboratory findings: Difference between revisions

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==Overview==
==Overview==
Laboratory tests are not usually performed for Erysipelas; physical examination is usually sufficient for diagnosis. However, certain laboratory tests may be performed on Erysipelas patients, including those used to confirm [[streptococcal]] infection. Erysipelas patients may display markers for [[inflammation]], such as [[leukocytosis]].


==Laboratory Findings==
==Laboratory Findings==
Laboratory tests and findings for Erysipelas include those used to confirm [[streptococcal]] infection for pathogenic strains.
Laboratory tests are not usually performed for Erysipelas; physical examination is usually sufficient for diagnosis. However, certain laboratory tests may be performed on Erysipelas patients, including those used to confirm [[streptococcal]] infection. An [[epidermal]] swab of affected region may provide samples of pathogenic [[streptococci]], including ''[[Streptococcus pyogenes]]''. Erysipelas laboratory findings include identification tests to determine the exact species of [[streptococcal]] infection.  


===Culture===
===Culture===
*Swab of affected region may provide samples of pathogenic [[streptococci]], including ''[[Streptococcus pyogenes]]''<ref name="pmid26866211">{{cite journal |vauthors=Ferretti JJ, Stevens DL, Fischetti VA, Stevens DL, Bryant AE |title= |journal= |volume= |issue= |pages= |year= |pmid=26866211 |doi= |url=}}</ref>
*An [[epidermal]] swab of affected region may provide samples of pathogenic [[streptococci]], including ''[[Streptococcus pyogenes]]''<ref name="pmid26866211">{{cite journal |vauthors=Ferretti JJ, Stevens DL, Fischetti VA, Stevens DL, Bryant AE |title= |journal= |volume= |issue= |pages= |year= |pmid=26866211 |doi= |url=}}</ref>
**[[Streptococci]] will usually be grown on agar media to produce β-[[hemolysis]] for subsequent identification and specification.
**[[Streptococci]] will usually be grown on agar media to produce β-[[hemolysis]] for subsequent identification and specification.
**''[[Streptococcus pyogenes]] will display as smooth, white-grey domes surrounded by β-[[hemolysis]].
**''[[Streptococcus pyogenes]]'' will display as smooth, white-grey domes surrounded by β-[[hemolysis]].
***They will be arranged in chain formation as [[Gram-positive]] [[cocci]] when examined microscopically.
***They will be arranged in chain formation as [[Gram-positive]] [[cocci]] when examined microscopically.
**[[Catalase]] testing will confirm that the isolates obtained through the culture swab represent [[streptococci]] infection.


===Streptococcal Identification Tests===
===Streptococcal Identification Tests===
*  
*Erysipelas laboratory findings include identification tests to determine the exact species of [[streptococcal]] infection.
**The [[Lancefield]] [[antigen]] test will determine the specific [[antibodies]] produced by the β-[[hemolytic]] [[streptococcal]] infection, allowing classification into group A, B, C, or G ''[[streptococcus]]''.
**The Pyrrolidonyl Arylamidase (PYR) test is used to determine if the infection is ''[[Streptococcus pyogenes]]'' by testing for confirmed presence of pyrrolidonyl [[aminopeptidase]]
**[[Bacitracin]] susceptibility testing is used as a next subsequent measure of specifying the [[streptococcal]] strain when PYR test results are positive, separating ''[[Streptococcal pyogenes]]'' from other β-[[hemolytic]] strains.
***Results of [[bacitracin]] sensitivity indicate positive ''[[Streptococcal pyogenes]]'' test results.<ref name="urlwww.cdc.gov">{{cite web |url=https://www.cdc.gov/streplab/downloads/general-methods-sections1-2.pdf |title=www.cdc.gov |format= |work= |accessdate=}}</ref>
 
===Evidence of Inflammation===
**Erysipelas patients may display markers for [[inflammation]], such as [[leukocytosis]]<ref name="pmid15581749">{{cite journal |vauthors=Musette P, Benichou J, Noblesse I, Hellot MF, Carvalho P, Young P, Levesque H, Courtois H, Caron F, Lauret P, Joly P |title=Determinants of severity for superficial cellutitis (erysipelas) of the leg: a retrospective study |journal=Eur. J. Intern. Med. |volume=15 |issue=7 |pages=446–450 |year=2004 |pmid=15581749 |doi=10.1016/j.ejim.2004.06.010 |url=}}</ref>, determined by the following tests:
***[[Erythrocyte sedimentation rate]]
***[[C-reactive protein]]


==References==
==References==

Latest revision as of 18:41, 5 October 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Laboratory tests are not usually performed for Erysipelas; physical examination is usually sufficient for diagnosis. However, certain laboratory tests may be performed on Erysipelas patients, including those used to confirm streptococcal infection. Erysipelas patients may display markers for inflammation, such as leukocytosis.

Laboratory Findings

Laboratory tests are not usually performed for Erysipelas; physical examination is usually sufficient for diagnosis. However, certain laboratory tests may be performed on Erysipelas patients, including those used to confirm streptococcal infection. An epidermal swab of affected region may provide samples of pathogenic streptococci, including Streptococcus pyogenes. Erysipelas laboratory findings include identification tests to determine the exact species of streptococcal infection.

Culture

Streptococcal Identification Tests

Evidence of Inflammation

References

  1. Ferretti JJ, Stevens DL, Fischetti VA, Stevens DL, Bryant AE. PMID 26866211. Missing or empty |title= (help)
  2. "www.cdc.gov" (PDF).
  3. Musette P, Benichou J, Noblesse I, Hellot MF, Carvalho P, Young P, Levesque H, Courtois H, Caron F, Lauret P, Joly P (2004). "Determinants of severity for superficial cellutitis (erysipelas) of the leg: a retrospective study". Eur. J. Intern. Med. 15 (7): 446–450. doi:10.1016/j.ejim.2004.06.010. PMID 15581749.

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