Ependymoma surgery: Difference between revisions

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{{CMG}} {{AE}} {{AAM}}
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==Overview==
==Overview==
Surgery is the main stay of treatment for myxopapillary ependymoma ([[WHO]] grade 1), myxopapillary ependymoma ([[WHO]] grade 1), ependymoma ([[WHO]] grade I), and anaplastic ependymoma ([[WHO]] grade III).
Surgery is the main stay of treatment for myxopapillary ependymoma ([[WHO]] grade 1), subependymoma ([[WHO]] grade 1), ependymoma ([[WHO]] grade I), and anaplastic ependymoma ([[WHO]] grade III).


==Surgery==
==Surgery==
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:*Newly diagnosed myxopapillary ependymoma ([[WHO]] grade 1)
:*Newly diagnosed myxopapillary ependymoma ([[WHO]] grade 1)
:*Newly diagnosed myxopapillary ependymoma ([[WHO]] grade 1)
:*Newly diagnosed subependymoma ([[WHO]] grade 1)
:*Newly diagnosed ependymoma ([[WHO]] grade I)
:*Newly diagnosed ependymoma ([[WHO]] grade I)
:*Newly diagnosed [[anaplastic]] ependymoma ([[WHO]] grade III)
:*Newly diagnosed [[anaplastic]] ependymoma ([[WHO]] grade III)


*Complete surgical removal is often curative. Some subependymomas are considered incidental findings and observed without intervention.
*Complete surgical removal is often curative. Some subependymomas are considered incidental findings and observed without intervention.
*Extensive surgical resection for anaplastic ependymoma ([[WHO]] grade III) in attempt to maximal tumor reduction is related to improved survival rate.<ref name="pmid827-35">{{cite journal| author=Tennyson VM, Mytilineou C, Heikkila R, Barrett RE, Cohen G, Côté L et al.| title=Dopamine-containing neurons of the substantia nigra and their terminals in the neostriatum. | journal=UCLA Forum Med Sci | year= 1975 | volume=  | issue= 18 | pages= 227-64 | pmid=827-35 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=827  }} </ref><ref name="pmid258-66">{{cite journal| author=Zourlas PA| title=Response to exogenous gonadotropins in the unresponsive ovary syndrome. | journal=Int J Gynaecol Obstet | year= 1975 | volume= 13 | issue= 1 | pages= 23-8 | pmid=258-66 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=258  }} </ref>
*Extensive surgical resection for anaplastic ependymoma ([[WHO]] grade III) in an attempt to maximize tumor resection is related to improved survival rate of patients.<ref name="pmid827-35">{{cite journal| author=Tennyson VM, Mytilineou C, Heikkila R, Barrett RE, Cohen G, Côté L et al.| title=Dopamine-containing neurons of the substantia nigra and their terminals in the neostriatum. | journal=UCLA Forum Med Sci | year= 1975 | volume=  | issue= 18 | pages= 227-64 | pmid=827-35 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=827  }} </ref><ref name="pmid258-66">{{cite journal| author=Zourlas PA| title=Response to exogenous gonadotropins in the unresponsive ovary syndrome. | journal=Int J Gynaecol Obstet | year= 1975 | volume= 13 | issue= 1 | pages= 23-8 | pmid=258-66 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=258  }} </ref>


==References==
==References==
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Latest revision as of 22:19, 26 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

Surgery is the main stay of treatment for myxopapillary ependymoma (WHO grade 1), subependymoma (WHO grade 1), ependymoma (WHO grade I), and anaplastic ependymoma (WHO grade III).

Surgery

  • Anecdotal experience suggests that surgery alone for completely resected supratentorial nonanaplastic tumors and intradural spinal cord ependymomas may be an appropriate approach to treatment for:[1]
  • Newly diagnosed myxopapillary ependymoma (WHO grade 1)
  • Newly diagnosed subependymoma (WHO grade 1)
  • Newly diagnosed ependymoma (WHO grade I)
  • Newly diagnosed anaplastic ependymoma (WHO grade III)
  • Complete surgical removal is often curative. Some subependymomas are considered incidental findings and observed without intervention.
  • Extensive surgical resection for anaplastic ependymoma (WHO grade III) in an attempt to maximize tumor resection is related to improved survival rate of patients.[2][3]

References

  1. Ependymoma http://www.cancer.gov/types/brain/hp/child-ependymoma-treatment-pdq/#cit/section_7.1 URL Accessed on 10 8 2015
  2. Tennyson VM, Mytilineou C, Heikkila R, Barrett RE, Cohen G, Côté L; et al. (1975). "Dopamine-containing neurons of the substantia nigra and their terminals in the neostriatum". UCLA Forum Med Sci (18): 227–64. PMID 827-35 Check |pmid= value (help).
  3. Zourlas PA (1975). "Response to exogenous gonadotropins in the unresponsive ovary syndrome". Int J Gynaecol Obstet. 13 (1): 23–8. PMID 258-66 Check |pmid= value (help).

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