Ependymoma surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

Surgery is the main stay of treatment for myxopapillary ependymoma (WHO grade 1), subependymoma (WHO grade 1), ependymoma (WHO grade I), and anaplastic ependymoma (WHO grade III).

Surgery

  • Anecdotal experience suggests that surgery alone for completely resected supratentorial nonanaplastic tumors and intradural spinal cord ependymomas may be an appropriate approach to treatment for:[1]
  • Newly diagnosed myxopapillary ependymoma (WHO grade 1)
  • Newly diagnosed subependymoma (WHO grade 1)
  • Newly diagnosed ependymoma (WHO grade I)
  • Newly diagnosed anaplastic ependymoma (WHO grade III)
  • Complete surgical removal is often curative. Some subependymomas are considered incidental findings and observed without intervention.
  • Extensive surgical resection for anaplastic ependymoma (WHO grade III) in an attempt to maximize tumor resection is related to improved survival rate of patients.[2][3]

References

  1. Ependymoma http://www.cancer.gov/types/brain/hp/child-ependymoma-treatment-pdq/#cit/section_7.1 URL Accessed on 10 8 2015
  2. Tennyson VM, Mytilineou C, Heikkila R, Barrett RE, Cohen G, Côté L et al. (1975). "Dopamine-containing neurons of the substantia nigra and their terminals in the neostriatum.". UCLA Forum Med Sci (18): 227-64. PMID 827-35.
  3. Zourlas PA (1975). "Response to exogenous gonadotropins in the unresponsive ovary syndrome.". Int J Gynaecol Obstet 13 (1): 23-8. PMID 258-66.

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