Ependymoma medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
* The malignant (anaplastic) varieties of this [[tumor]], malignant ependymoma and the ependymoblastoma, are treated similarly to [[medulloblastoma]] but the prognosis is much less favorable. Malignant ependymomas may be treated with a combination of radiation therapy and chemotherapy. | * The malignant (anaplastic) varieties of this [[tumor]], malignant ependymoma and the ependymoblastoma, are treated similarly to [[medulloblastoma]] but the prognosis is much less favorable. Malignant ependymomas may be treated with a combination of radiation therapy and chemotherapy. | ||
==Radiation Therapy== | ==Radiation Therapy== | ||
* | *Radiation therapy consisting of 54 Gy to 55.8 Gy is recommended for children aged 3 years and older who are diagnosed with well-differentiated ependymomas.<ref name="pmid583-90">{{cite journal| author=Diewitz M| title=[Coronary heart disease and its differential treatment]. | journal=Med Welt | year= 1975 | volume= 26 | issue= 43 | pages= 1980-8 | pmid=583-90 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prl | ||
*It is not necessary to treat the entire CNS (whole brain and spine) because these tumors usually recur initially at the local site.<ref name="pmid972-8">{{cite journal| author=De Dobbeleer GD, Ledoux-Corbusier MH, Achten GA| title=Graft versus host reaction. An ultrastructural study. | journal=Arch Dermatol | year= 1975 | volume= 111 | issue= 12 | pages= 1597-902 | pmid=972-8 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=972 }} </ref><ref name="pmid987-93">{{cite journal| author=Colwell WM, Simmons DG, Harris JR, Fulp TG, Carrozza JH, Maag TA| title=Influence of some physical factors on survival of Marek's disease vaccine virus. | journal=Avian Dis | year= 1975 | volume= 19 | issue= 4 | pages= 781-90 | pmid=987-93 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=987 }} </ref> | |||
*When possible, patients should be treated in a center experienced with the delivery of highly conformal radiation therapy (including intensity-modulated radiation therapy or charged-particle radiation therapy) to pediatric patients with brain tumors. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 17:41, 8 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Medical Therapy
- The malignant (anaplastic) varieties of this tumor, malignant ependymoma and the ependymoblastoma, are treated similarly to medulloblastoma but the prognosis is much less favorable. Malignant ependymomas may be treated with a combination of radiation therapy and chemotherapy.
Radiation Therapy
- Radiation therapy consisting of 54 Gy to 55.8 Gy is recommended for children aged 3 years and older who are diagnosed with well-differentiated ependymomas.[1]
- When possible, patients should be treated in a center experienced with the delivery of highly conformal radiation therapy (including intensity-modulated radiation therapy or charged-particle radiation therapy) to pediatric patients with brain tumors.
References
- ↑ Colwell WM, Simmons DG, Harris JR, Fulp TG, Carrozza JH, Maag TA (1975). "Influence of some physical factors on survival of Marek's disease vaccine virus". Avian Dis. 19 (4): 781–90. PMID 987-93 Check
|pmid=value (help).