Differentiating Diabetes mellitus type 2 from other diseases: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
Line 32: Line 32:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 1|Type 1 Diabetes mellitus]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 1|Type 1 Diabetes mellitus]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
Line 48: Line 48:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 2|Type 2 Diabetes mellitus]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 2|Type 2 Diabetes mellitus]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
Line 64: Line 64:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[MODY]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[MODY]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
Line 80: Line 80:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Psychogenic polydipsia]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Psychogenic polydipsia]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
Line 96: Line 96:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes insipidus]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes insipidus]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
Line 128: Line 128:
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Steroid]] therapy
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Steroid]] therapy
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
Line 141: Line 141:
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Acanthosis nigricans|Acanthosis nigricans]]  
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Acanthosis nigricans|Acanthosis nigricans,]]  
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[RTA|RTA 1]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[RTA|RTA 1]]
Line 147: Line 147:
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |Normal
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |Normal
Line 180: Line 180:
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |✔
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
Line 191: Line 191:
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Moon face]], [[obesity]], [[buffalo hump]], easy [[Bruising|bruisibility]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Moon face]], [[obesity]], [[buffalo hump]], easy [[Bruising|bruisibility]]
|}
|}


==References==
==References==

Revision as of 14:29, 30 March 2017

Diabetes mellitus main page

Diabetes mellitus type 2 Microchapters

Home

Patient information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Diabetes Mellitus Type 2 from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical therapy

Life Style Modification
Pharmacotherapy
Glycemic Control

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

Type 2 diabetes mellitus must be differentiated from other disorders that may present with polyuria, polydipsia, weight loss or weight gain. Such disorders may include other forms of diabetes mellitus (e.g. type 1 DM, MODY) or other endocrine disorders (e.g. hypothyroidism, cushings syndrome, wolfram syndrome, alstrom syndrome) or drug

Differentiating Diabetes Mellitus Type 2 from other Diseases

Type 2 DM must be differentiated from other forms of diabetes mellitus as well as other endocrine disorders based on the syptoms and laboratory findings.[1][2][3] The following table shows the appropriate history and symptoms and laboratory findings that may distinguish type 2 DM from other diseases:


Disease History and symptoms Laboratory findings Additional findings
Polyuria Polydipsia Polyphagia Weight loss Weight gain Serum glucose Urinary Glucose Urine PH Serum Sodium Urinary Glucose 24 hrs cortisol level C-peptide level Serum glucagon
Type 1 Diabetes mellitus + + + + - ↑ ↑ Normal Normal N/↑ Normal ↓ Normal Auto antibodies present (Anti GAD-65 and anti insulin anti bodies)
Type 2 Diabetes mellitus + + + + - ↑ ↑ Normal Normal ↑ Normal Normal ↑ Acanthosis nigricans
MODY + + + - + ↑ ↑ Normal Normal ↑ Normal Normal N -
Psychogenic polydipsia + + - - - Normal Normal Normal ↓ Normal Normal Normal Normal -
Diabetes insipidus + + - - - Normal Normal Normal ↑ Normal Normal Normal Normal -
Transient hyperglycemia - - - - - ↑ ↑ Normal Normal ↑ Normal Normal N/↑ In hospitalized patients especially in ICU and CCU
Steroid therapy + - - - + ↑ ↑ Normal Normal ↑ ↑ N/↑ N/↑ Acanthosis nigricans,
RTA 1 - - - + - Normal Normal ↑ Normal ↑ Normal Normal Normal Hypokalemia, nephrolithiasis
Glucagonoma - - - - - ↑ Normal Normal Normal - Normal Normal ↑ Necrolytic migratory erythema
Cushing syndrome - - - - + ↑ - Normal ↓ N/↑ ↑ Normal Normal Moon face, obesity, buffalo hump, easy bruisibility

References

  1. ↑ Barrett TG (2007). "Differential diagnosis of type 1 diabetes: which genetic syndromes need to be considered?". Pediatr Diabetes. 8 Suppl 6: 15–23. doi:10.1111/j.1399-5448.2007.00278.x. PMID 17727381.
  2. ↑ Type 1 Diabetes mellitus "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on December 27th,2016
  3. ↑ "namrata".

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Differentiating_Diabetes_mellitus_type_2_from_other_diseases&oldid=1303581"