Chronic lymphocytic leukemia natural history, complications and prognosis: Difference between revisions
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{{Chronic lymphocytic leukemia}} | {{Chronic lymphocytic leukemia}} | ||
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==Overview== | ==Overview== | ||
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The prognosis of chronic lymphocytic leukemia depends on: | The prognosis of chronic lymphocytic leukemia depends on: | ||
*The stage of chronic lymphocytic leukemia, whether lymphocytes are spread throughout the bone marrow, whether the chronic lymphocytic leukemia progresses to lymphoma or prolymphocytic leukemia. | * The stage of chronic lymphocytic leukemia, whether lymphocytes are spread throughout the bone marrow, whether the chronic lymphocytic leukemia progresses to lymphoma or prolymphocytic leukemia. | ||
*Treatment response: Whether the chronic lymphocytic leukemia patient gets better with treatment or has come back. | * Treatment response: Whether the chronic lymphocytic leukemia patient gets better with treatment or has come back. | ||
*The patient's general health. | * The patient's general health. | ||
Survival varies from 5 years to more than 25 years. | Survival varies from 5 years to more than 25 years. | ||
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{{Hematological malignancy histology}} | {{Hematological malignancy histology}} | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} |
Revision as of 12:26, 7 August 2012
Chronic lymphocytic leukemia Microchapters |
Differentiating Chronic lymphocytic leukemia from other Diseases |
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Chronic lymphocytic leukemia natural history, complications and prognosis On the Web |
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Directions to Hospitals Treating Chronic lymphocytic leukemia |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Natural History, Complications and Prognosis
Complications
- Hypogammaglobulinemia leading to recurrent infection.
- Autoimmune hemolytic anemia - IgG type
- Transformation to high grade lymphoma
- Richter's transformation
- Gastrointestinal (GI) involvement - intussusception, small intestinal bacterial contamination, colitis
- Increased risk of other cancers - melanoma, lung and gastrointestinal cancers
Prognosis
The prognosis of chronic lymphocytic leukemia depends on:
- The stage of chronic lymphocytic leukemia, whether lymphocytes are spread throughout the bone marrow, whether the chronic lymphocytic leukemia progresses to lymphoma or prolymphocytic leukemia.
- Treatment response: Whether the chronic lymphocytic leukemia patient gets better with treatment or has come back.
- The patient's general health.
Survival varies from 5 years to more than 25 years.
References