Chronic lymphocytic leukemia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

  • The most potent risk factor in the development of chronic lymphocytic leukemia is advanced age. Other risk factors include male gender, positive family history, and exposure to certain chemicals.

Risk Factors

  • The most potent risk factor in the development of chronic lymphocytic leukemia is advanced age. Other risk factors include male gender, positive family history, and exposure to certain chemicals.
  • The table below lists the risk factors involved in the development of chronic lymphocytic leukemia:[1][2]
Risk Factor Description
Age The risk to develop chronic lymphocytic leukemia increases as patients advance in age.
Gender Males are more commonly affected with chronic lymphocytic leukemia than females.
Family history First-degree relatives of chronic lymphocytic leukemia patients have an increased risk to develop to the disease.
Chemical exposure Exposure to herbicides and insecticides (used in farming) is correlated with an increased risk of chronic lymphocytic leukemia.

References

  1. Karakosta M, Delicha EM, Kouraklis G, Manola KN (November 2016). "Association of various risk factors with chronic lymphocytic leukemia and its cytogenetic characteristics". Arch Environ Occup Health. 71 (6): 317–329. doi:10.1080/19338244.2015.1116429. PMID 26566973.
  2. Brown JR (October 2008). "Inherited predisposition to chronic lymphocytic leukemia". Expert Rev Hematol. 1 (1): 51–61. doi:10.1586/17474086.1.1.51. PMC 2732130. PMID 19802369.

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