Hemophilia MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

MRI may be helpful in the diagnosis of hemophilia. Findings on MRI suggestive of hemophilic arthropathy include effusion, synovial hyperplasia, erosion, subchondral cyst, cartilage loss, osteonecrosis, fibrocartilage tear, ligament tear, loose body.

MRI

The additive European MRI scoring system[1]

Type of change Score

Subchondral cysts

  • Present in at least one bone
  • Present in at least two bones
  • More than three cysts in at least one bone
  • More than three cysts in at least two bones
  • Largest size > 4 mm in at least one bone
  • Largest size > 4 mm in at least two bones


  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Enlargement of epiphysis
  • Absent = 0
  • Present = 1
Irregularity of subchondral surface
  • Absent = 0
  • Partially involved = 1
  • Totally involved = 2
Narrowing of joint space
  • Absent = 0
  • Joint space > 1 mm = 1
  • Joint space < 1 mm = 2
Subchondral cysts formation
  • Absent = 0
  • 1 cyst = 1
  • >1 cyst = 2
Erosion of joint margins
  • Absent = 0
  • Present = 1
Gross incongruence of articulating bone ends
  • Absent = 0
  • Slight = 1
  • Pronounced = 2
Joint deformity (angulation and/or displacement)
  • Absent = 0
  • Slight = 1
  • Pronounced = 2


References

  1. Lundin B, Pettersson H, Ljung R (July 2004). "A new magnetic resonance imaging scoring method for assessment of haemophilic arthropathy". Haemophilia. 10 (4): 383–9. doi:10.1111/j.1365-2516.2004.00902.x. PMID 15230954.

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