Short bowel syndrome medical therapy

Jump to navigation Jump to search

Short bowel syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Short bowel syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Short bowel syndrome medical therapy On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Short bowel syndrome medical therapy

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Short bowel syndrome medical therapy

CDC on Short bowel syndrome medical therapy

Short bowel syndrome medical therapy in the news

Blogs on Short bowel syndrome medical therapy

Directions to Hospitals Treating Short bowel syndrome

Risk calculators and risk factors for Short bowel syndrome medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Medical Therapy

  • Management of short bowel syndrome is complicated and requires close collaboration of all medical team members including the physician, nutritionist, and nurse with the patient and their families.
  • Management of short bowel syndrome consists of medical therapy and surgical interventions.
  • Medical therapy consists of nutritional therapy and pharmacotherapy.
  • Lifelong follow-up is usually needed.

Nutritional therapy

  • Nutritional therapy is essential for short bowel syndrome and to restore the intestinal adaptation. It could be provided through oral, enteral and parenteral routes.
    • 1 Fluid
      • 1.1 Acute phase
        • Preferred regimen (1): drug name 100 mg PO q12h for 10-21 days (Contraindications/specific instructions)
        • Preferred regimen (1): drug name 100 mg PO q12h for 10-21 days (Contraindications/specific instructions)
      • 1.2 Maintenance phase
        • Preferred regimen (1): drug name 100 mg PO q12h for 10-21 days (Contraindications/specific instructions)
        • Alternative regimen (1): drug name 500 mg PO q6h for 7–10 days
    • 2 Parenteral infusion
      • 2.1 Acute phase
        • 2.1.1 Diet
          • Preferred regimen (1): drug name 50 mg/kg PO per day q8h (maximum, 500 mg per dose)
          • Preferred regimen (2): drug name 30 mg/kg PO per day in 2 divided doses (maximum, 500 mg per dose)
          • Alternative regimen (1): drug name10 mg/kg PO q6h (maximum, 500 mg per day)
          • Alternative regimen (2): drug name 7.5 mg/kg PO q12h (maximum, 500 mg per dose)
        • 2.1.2 Electrolytes
      • 2.2 Maintenance phase
        • Preferred regimen (1): drug name 4 mg/kg/day PO q12h(maximum, 100 mg per dose)
        • Alternative regimen (1): drug name 10 mg/kg PO q6h (maximum, 500 mg per day)
        • Alternative regimen (2): drug name 7.5 mg/kg PO q12h (maximum, 500 mg per dose)
        • Alternative regimen (3): drug name 12.5 mg/kg PO q6h (maximum, 500 mg per dose)
    • 3 Enteral nutrition
      • 1.2.1 Adult
        • Preferred regimen (1): drug name 500 mg PO q8h
      • 1.2.2 Pediatric
        • Preferred regimen (1): drug name 50 mg/kg/day PO q8h (maximum, 500 mg per dose)
    • 4 Supplement
      • 4.1 Vitamins
      • 4.2 Minerals
      • 4.3 Exogenous enzyme replacement 
        • 4.3.1 Pancreatic enzyme
        • 4.3.2 Lactase
      • 4.4 Bile acid sequestrants

Pharmacotherapy

Symptoms of short bowel syndrome are usually addressed by prescription medicine. These include:

References