Leprosy differential diagnosis: Difference between revisions
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* [[Dermatophyte]] - [[parasitic]] [[fungus]] that [[infects]] the the [[skin]], [[hair]] and [[nails]] due to its ability to obtain [[nutrients]] from [[keratinized]] material. The infection is usually restricted to the nonliving cornified layer of the [[epidermis]] because of their inability to penetrate viable tissue of an [[immunocompetent]] host. | * [[Dermatophyte]] - [[parasitic]] [[fungus]] that [[infects]] the the [[skin]], [[hair]] and [[nails]] due to its ability to obtain [[nutrients]] from [[keratinized]] material. The infection is usually restricted to the nonliving cornified layer of the [[epidermis]] because of their inability to penetrate viable tissue of an [[immunocompetent]] host. | ||
* [[Systemic Lupus Erythematosus]] - potential fatal [[chronic]] [[autoimmune disease]] | * [[Systemic Lupus Erythematosus]] - potential fatal [[chronic]] [[autoimmune disease]], common initial and [[chronic]] complaints include [[skin rash]], [[fever]], [[malaise]], [[arthralgia|joint pains]], [[myalgia]]s and [[Fatigue (medical)|fatigue]. | ||
* [[Postinflammatory hypopigmented]] skin - | * [[Postinflammatory hypopigmented]] skin - |
Revision as of 18:53, 4 July 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Differential diagnosis
Leprosy may have a wide range of manifestations, each with different degrees of intensity. The diagnosis of leprosy may be hard to reach, particularly in non endemic areas, or where there is a very low prevalence of the disease. However, by acknowledging the potential diagnosis of leprosy, being familiarized and following the adequate steps for the diagnosis of this condition, will facilitate the diagnostic process. Other diseases that may mimic, or have similar features with leprosy, include:[1]
- Congenital lesions - such as nevus depigmentosus are generally present at birth and do not present with changes in sensation.
- Vitiligo - a benign lesion that presents with depigmented areas, instead of hypopigmented.
- Pityriasis alba - may be hard to distinguish from leprosy, particularly in early stages of the second, however, it is a common skin condition mostly occurring in children and usually seen as dry, fine scaled, pale patches on their faces.[2]
- Pityriasis versicolor - common skin infection caused by the yeast Malassezia furfur. This yeast is normally found on the human skin and only becomes troublesome under certain circumstances, such as a warm and humid environment, causing: generally oval or irregularly-shaped spots of 1/4 to 1 inch in diameter, often merging together to form a larger patch with a sharp border; occasional fine scaling of the skin producing a very superficial ash-like scale; and pale, dark tan, or pink in color spots, with a reddish undertone that can darken when the patient is overheated, such as in a hot shower or during/after exercise.
- Dermatophyte - parasitic fungus that infects the the skin, hair and nails due to its ability to obtain nutrients from keratinized material. The infection is usually restricted to the nonliving cornified layer of the epidermis because of their inability to penetrate viable tissue of an immunocompetent host.
- Systemic Lupus Erythematosus - potential fatal chronic autoimmune disease, common initial and chronic complaints include skin rash, fever, malaise, joint pains, myalgias and [[Fatigue (medical)|fatigue].
- Hereditary sensory motor neuron neuropathy type III -
- Amyloid -
- Keloid -