Mast cell tumor natural history, complications and prognosis: Difference between revisions
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==Complications== | ==Complications== | ||
Common complications of mast cell tumor include: | |||
*[[Anaphylaxis]] | *[[Anaphylaxis]] | ||
*[[Osteoporosis]] | *[[Osteoporosis]] | ||
*Systemic mastocytosis may progress to malignant mastocytosis and/ or mast cell leukemia | *Systemic mastocytosis may progress to malignant mastocytosis and/ or mast cell leukemia | ||
==Prognosis== | ==Prognosis== | ||
Revision as of 18:55, 7 March 2016
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Overview
Natural History
- Mast cell tumor usually occurs as a sporadic disease that is often transient and limited in children and progressive in adults.
- Systemic mastocytosis may develop in childhood cases of urticaria pigmentosa that persist beyond puberty, and in approximately 40% of adults with urticaria pigmentosa, usually of long standing.
- Patients with mast cell tumor often initially have symptom-free intervals interspersed among symptomatic periods.
- Over time, symptom-free intervals shorten, and finally symptoms become chronic with intensity which fluctuates but with an overall trend toward steadily increasing intensity.
Complications
Common complications of mast cell tumor include:
- Anaphylaxis
- Osteoporosis
- Systemic mastocytosis may progress to malignant mastocytosis and/ or mast cell leukemia