Urticaria causes: Difference between revisions

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==Overview==
[[Urticaria]] may be caused [[idiopathic|idiopathically]] or due to [[immunology|immunological disorders]] such as [[autoimmune diseases]], [[food allergies]], [[medications]] and specific [[infections]]. There are also some non-[[immunology|immunological]] causes for [[urticaria]] development, such as physical triggers, [[Diet (nutrition)|dietary]] pseudo-[[allergen]] and [[urticaria|hereditary urticaria]].
==Causes==
==Causes==
Many substances can trigger hives, including:
===Common Causes===
*Animal dander (especially cats)
Common causes of [[urticaria]] may include:<ref name="pmid18713139">{{cite journal| author=Deacock SJ| title=An approach to the patient with urticaria. | journal=Clin Exp Immunol | year= 2008 | volume= 153 | issue= 2 | pages= 151-61 | pmid=18713139 | doi=10.1111/j.1365-2249.2008.03693.x | pmc=2492902 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18713139  }} </ref><ref name="pmid8258619">{{cite journal| author=Erben AM, Rodriguez JL, McCullough J, Ownby DR| title=Anaphylaxis after ingestion of beignets contaminated with Dermatophagoides farinae. | journal=J Allergy Clin Immunol | year= 1993 | volume= 92 | issue= 6 | pages= 846-9 | pmid=8258619 | doi=10.1016/0091-6749(93)90062-k | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8258619  }} </ref><ref name="pmid8732238">{{cite journal| author=Beezhold DH, Sussman GL, Liss GM, Chang NS| title=Latex allergy can induce clinical reactions to specific foods. | journal=Clin Exp Allergy | year= 1996 | volume= 26 | issue= 4 | pages= 416-22 | pmid=8732238 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8732238  }} </ref><ref name="pmid31180381">{{cite journal| author=Kayiran MA, Akdeniz N| title=Diagnosis and treatment of urticaria in primary care. | journal=North Clin Istanb | year= 2019 | volume= 6 | issue= 1 | pages= 93-99 | pmid=31180381 | doi=10.14744/nci.2018.75010 | pmc=6526977 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31180381  }} </ref>
*Insect bites
*Medications
:*[[Dexamethasone]]
:*[[Prednisone]]
:*[[caspofungin acetate]]
:*[[Doxycycline]]
:*[[Doxycycline]]
:*[[Hydrochlorothiazide]]
:*[[Spironolactone]]
:*[[Tolbutamide]]
*Pollen
*Shellfish, fish, nuts, eggs, milk, and other foods


Hives may also develop as a result of:
*[[Idiopathic]]
*Emotional stress
**Unknown [[etiology]]
*Extreme cold or sun exposure
*[[immunology|Immunological]]:
*Excessive perspiration
**[[Autoimmune]]: [[Immunoglobulin G|IgG]] [[Autoantibody|autoantibodies]] to [[Immunoglobulin G|IgE]] receptor or [[Immunoglobulin G|IgE]] on [[Mast cell|mast cells]] could be the responsible mechanism.
*Illness (including [[lupus]], other autoimmune diseases, and [[leukemia]])
**[[Immunoglobulin E|IgE]]/[[urticaria|contact urticaria]]:
*Infections such as [[mononucleosis]]
***Contact with [[allergen]] cross-links specific [[Immunoglobulin E|IgE]] ([[Immunoglobulin E|SIgE]]) on [[mast cell|mast cells]].
***Could be due to food [[protein]] [[antigen|antigens]] (such a [[mold]] or storage [[mite]]), insect [[Venom|venoms]], animal dander's and/or [[saliva]], [[penicillin]], protease [[Enzyme|enzymes]] in [[Biology|biological]] [[detergents]] and [[Latex allergy|latex proteins]].
***In [[patient|patients]] with [[urticaria]] due to [[latex allergy]], there is a higher chance of a wide variety of food [[allergy]] due to [[cross-reactivity]] between the [[Latex allergy|latex protein]] [[antigen|antigens]] and food [[antigen|antigens]]. The following list is a summary of foods capable of [[cross-reactivity]] with [[latex]] [[proteins]]:
 
<br>
{{Family tree/start}}
{{familytree  |boxstyle=background: #FFFF00; color: #F8F8FF;| | | | | B01 | | | | | B01=<div style="float: left; text-align: left; height: 20em; width: 22em; padding:1em;"> '''<span style="color:navy;">The items:</span>'''<br>
----
<span style="color:navy;">❑</span> <span style="color:navy;">High frequency of cross-reactivity, such as avocado, banana and chestnut</span> <br> <span style="color:navy;">❑</span> <span style="color:navy;">Moderate frequency of cross-reactivity such as apple, carrot, celery, kiwi, melon, papaya, potato and tomato</span> <br><span style="color:navy;">❑</span> <span style="color:navy;">Low frequency of cross-reactivity, such as apricot, cherry, fig, grape, hazelnut, mango, nectarine, passion fruit, peach, peanut, pear, plum, pineapple, soybean, strawberry and walnut.
</span> </div>}}
{{familytree/end}}
<br>
 
**[[Food allergy]]:<ref name="pmid18713139">{{cite journal| author=Deacock SJ| title=An approach to the patient with urticaria. | journal=Clin Exp Immunol | year= 2008 | volume= 153 | issue= 2 | pages= 151-61 | pmid=18713139 | doi=10.1111/j.1365-2249.2008.03693.x | pmc=2492902 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18713139  }} </ref> <ref name="pmid24607044">{{cite journal| author=Rajan JP, Simon RA, Bosso JV| title=Prevalence of sensitivity to food and drug additives in patients with chronic idiopathic urticaria. | journal=J Allergy Clin Immunol Pract | year= 2014 | volume= 2 | issue= 2 | pages= 168-71 | pmid=24607044 | doi=10.1016/j.jaip.2013.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24607044  }} </ref>
***Studies suggest that foods such as nuts, [[seafood]] (such as [[shellfish]]), eggs (especially egg white), fish, meat, chocolate, cow’s milk, fruits (such as [[citrus]] fruits, plums, pineapples, grapes, apples, bananas, and strawberries), vegetables (such as tomatoes, peas, garlic, onion, beans, and carrot), mushrooms, fermented foods, spirits and spices are capable of causing [[urticaria]].
***Although [[food allergy]] is known as a less common cause of adult [[urticaria]], it is a common cause of [[urticaria]] in children. In a study done on adults with [[urticaria]], 63% of [[patients]] suspected foods to be the reason of their [[symptoms]], however [[food allergy]] was responsible for [[urticaria]] development in only 0.9% of them.
**[[medications]]:  
***Sensitivity to [[Cyclooxygenase|Cyclo-oxygenase]] ([[Cyclooxygenase|COX]])-inhibitors ([[aspirin]], [[Non-steroidal anti-inflammatory drug|NSAIDs]])
***[[Penicillin]]
***[[thiazide|Thiazide diuretics]]
***[[Oral contraceptives]]
***[[ACE inhibitor|Angiotensin-converting enzyme inhibitors]]
***[[Sulfonamide (medicine)|Sulfonamides]]
***[[Vitamins]]
***[[Codeine]] and [[morphine]]
***[[Curare|Curare and its derivatives]]
***[[Adrenocorticotropic hormone|Synthetic adrenocorticotropic hormone]]
***[[Contrast medium|Radiocontrast substances]]
***[[Acetylcysteine]]
***[[Aminohippurate]]
***[[Antimalarial drug|Antimalarial drugs]], such as [[atovaquone and proguanil hydrochloride]] or [[artemether and lumefantrin]]
***[[Aztreonam]]
***[[Benzphetamine]]
***[[Boceprevir]]
***[[Penciclovir]]
***[[Polidocanol]]
***[[Probenecid]]
***[[Carbinoxamine]]
***[[Cephalosporins]], such as [[Cefoxitin sodium]] and [[Cefotaxime sodium]]
***[[Clobazam]]
***[[Dexamethasone]] and [[Prednisone]]
***[[Doxorubicin hydrochloride]]
***[[Lamivudine]]
***[[Dextran]]
***[[Caspofungin]]
***[[Oxaprozin]]
***[[Dapsone]]
***[[Idursulfase]]
***[[Tetracycline]]
***[[Tiagabine]]
***[[Tolbutamide]]
***[[Ferric Carboxymaltose]]
***[[Flavoxate]]
***[[Rifampin]]
***[[Pegademase]]
***[[Pegaspargase]]
***[[Streptomycin]]
***[[Indinavir]] and [[ritonavir]]
***[[Ivermectin]]
***[[Sulfamethoxazole/Trimethoprim (oral)]]
***[[Spironolactone]]
***[[Lidocaine (ointment)]]
***[[Lincomycin Hydrochloride]]
***[[Meropenem]]
***[[Niacin]]
***[[Nizatidine]]
***[[Von Willebrand factor]]
***[[Hepatitis B immunoglobulin]]
**[[infection|Infections]]<ref name="pmid31180381">{{cite journal| author=Kayiran MA, Akdeniz N| title=Diagnosis and treatment of urticaria in primary care. | journal=North Clin Istanb | year= 2019 | volume= 6 | issue= 1 | pages= 93-99 | pmid=31180381 | doi=10.14744/nci.2018.75010 | pmc=6526977 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31180381  }} </ref><ref name="pmid10695557">{{cite journal| author=Wedi B, Kapp A| title=Helicobacter pylori infection and skin diseases. | journal=J Physiol Pharmacol | year= 1999 | volume= 50 | issue= 5 | pages= 753-76 | pmid=10695557 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10695557  }} </ref><ref name="pmid21352335">{{cite journal| author=Akashi R, Ishiguro N, Shimizu S, Kawashima M| title=Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. | journal=J Dermatol | year= 2011 | volume= 38 | issue= 8 | pages= 761-6 | pmid=21352335 | doi=10.1111/j.1346-8138.2010.01106.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21352335  }} </ref><ref name="pmid21341171">{{cite journal| author=Karaman U, Sener S, Calık S, Saşmaz S| title=[Investigation of microsporidia in patients with acute and chronic urticaria]. | journal=Mikrobiyol Bul | year= 2011 | volume= 45 | issue= 1 | pages= 168-73 | pmid=21341171 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21341171  }} </ref> 
***[[infection|Viral infections]] are the most common cause of [[urticaria|acute urticaria]], mainly [[upper respiratory tract]] [[infections]], such as [[tonsillitis]] and [[rhinosinusitis]]. [[Prevalence]] of [[upper respiratory tract]] [[infections]] in [[urticaria|acute urticaria]] has been estimated between 28 to 62%, based on reports of five studies.
***[[Urinary tract infections]]
***[[Parasitism]]
***[[Hepatitis]]
***[[Mononucleosis|Infectious mononucleosis]]
***[[Tooth abscess|Dental abscesses]]
***[[Helicobacter pylori]] [[infection]]
***[[Syphilis]]
***[[Lyme disease]]
***[[Varicella]]
***[[HIV AIDS|HIV infection]]
**[[urticaria|Urticarial vasculitis]]<ref name="pmid14616095">{{cite journal| author=Zuberbier T| title=Urticaria. | journal=Allergy | year= 2003 | volume= 58 | issue= 12 | pages= 1224-34 | pmid=14616095 | doi=10.1046/j.1398-9995.2003.00327.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14616095  }} </ref>
*Non-[[immunology|immunological]]:
**[[urticaria|Physical urticaria]]: Physical factors trigger [[histamine]] release from [[mast cell|mast cells]].
**[[Diet (nutrition)|Dietary]] pseudo-[[allergen]]:<ref name="pmid18713139">{{cite journal| author=Deacock SJ| title=An approach to the patient with urticaria. | journal=Clin Exp Immunol | year= 2008 | volume= 153 | issue= 2 | pages= 151-61 | pmid=18713139 | doi=10.1111/j.1365-2249.2008.03693.x | pmc=2492902 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18713139  }} </ref><ref name="pmid952737">{{cite journal| author=Ros AM, Juhlin L, Michaëlsson G| title=A follow-up study of patients with recurrent urticaria and hypersensitivity to aspirin, benzoates and azo dyes. | journal=Br J Dermatol | year= 1976 | volume= 95 | issue= 1 | pages= 19-24 | pmid=952737 | doi=10.1111/j.1365-2133.1976.tb15532.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=952737  }} </ref><ref name="pmid1997836">{{cite journal| author=Morrow JD, Margolies GR, Rowland J, Roberts LJ| title=Evidence that histamine is the causative toxin of scombroid-fish poisoning. | journal=N Engl J Med | year= 1991 | volume= 324 | issue= 11 | pages= 716-20 | pmid=1997836 | doi=10.1056/NEJM199103143241102 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1997836  }} </ref><ref name="pmid31180381">{{cite journal| author=Kayiran MA, Akdeniz N| title=Diagnosis and treatment of urticaria in primary care. | journal=North Clin Istanb | year= 2019 | volume= 6 | issue= 1 | pages= 93-99 | pmid=31180381 | doi=10.14744/nci.2018.75010 | pmc=6526977 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31180381  }} </ref><ref name="pmid14616095">{{cite journal| author=Zuberbier T| title=Urticaria. | journal=Allergy | year= 2003 | volume= 58 | issue= 12 | pages= 1224-34 | pmid=14616095 | doi=10.1046/j.1398-9995.2003.00327.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14616095  }} </ref><ref name="pmid8869688">{{cite journal| author=Zuberbier T, Iffländer J, Semmler C, Henz BM| title=Acute urticaria: clinical aspects and therapeutic responsiveness. | journal=Acta Derm Venereol | year= 1996 | volume= 76 | issue= 4 | pages= 295-7 | pmid=8869688 | doi=10.2340/0001555576295297 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8869688  }} </ref>
***[[Sensitivity (tests)|Sensitivity]] to natural [[Salicylic acid|salicylates]], colorings (both [[Azo compound|azo dyes]] and non-[[Azo compound|azo dyes]]), [[preservatives]] (such as [[sulphite|sulphites]], [[Nitrate|nitrates]] and [[nitrites]]), [[Antioxidant|anti-oxidants]] (such as [[Butylated hydroxyanisole|butylated hydroxyanisole]] ([[Butylated hydroxyanisole|BHA]]) and [[Butylated hydroxytoluene|butylated hydroxytoluene]] ([[Butylated hydroxytoluene|BHT]])) and [[aspartame]] (an [[Sugar substitute|artificial sweetener]]).
***[[Histamine]] [[Poison|poisoning]] is one of the non-[[immunoglobulin E|IgE]]-mediated food-related [[urticaria]], which occur when foods have high [[histamine|histamine content]], such as improperly stored [[Scombroid|scombroid fish]] (such as [[Scombroid|mackerel, tuna and swordfish]]), with high level of [[Histidine|decarboxylated histidine]] due to [[Bacteria|bacterial activities]]. [[Histidine|Decarboxylated histidine]] then produces [[histamine]]. Although spoiled non-scombroid fish, such as herring, sardines and anchovies can also be responsible, due to high [[histamine]] content.
**[[Mold]] spores, pollen, [[mites]], animal [[hair]] and [[dandruff]] and other [[Allergen|respiratory allergens]] might cause [[urticaria]] through [[Breathing|respiration]]. Furthermore, [[smoking]] is related to [[urticaria]] development.<ref name="pmid31180381">{{cite journal| author=Kayiran MA, Akdeniz N| title=Diagnosis and treatment of urticaria in primary care. | journal=North Clin Istanb | year= 2019 | volume= 6 | issue= 1 | pages= 93-99 | pmid=31180381 | doi=10.14744/nci.2018.75010 | pmc=6526977 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31180381  }} </ref>
**[[urticaria|Hereditary urticaria]]
**[[Medicine|Medical conditions]]:
***[[urticaria|Urticaria pigmentosa]]: Increased [[mast cell]] load
***[[Cryopyrin-associated periodic syndrome|Cryopyrin-associated periodic syndrome]] ([[Cryopyrin-associated periodic syndrome|CAPS]]): Due to a [[mutation]] in CIAS1 [[gene]].
***[[Urticaria|Familial form of cold-induced urticaria]]<ref name="pmid66242">{{cite journal| author=Soter NA, Joshi NP, Twarog FJ, Zeiger RS, Rothman PM, Colten HR| title=Delayed cold-induced urticaria: a dominantly inherited disorder. | journal=J Allergy Clin Immunol | year= 1977 | volume= 59 | issue= 4 | pages= 294-7 | pmid=66242 | doi=10.1016/0091-6749(77)90050-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=66242  }} </ref>
***[[Mental disorders]]<ref name="pmid21597672">{{cite journal| author=Staubach P, Dechene M, Metz M, Magerl M, Siebenhaar F, Weller K | display-authors=etal| title=High prevalence of mental disorders and emotional distress in patients with chronic spontaneous urticaria. | journal=Acta Derm Venereol | year= 2011 | volume= 91 | issue= 5 | pages= 557-61 | pmid=21597672 | doi=10.2340/00015555-1109 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21597672  }} </ref><ref name="pmid31180381">{{cite journal| author=Kayiran MA, Akdeniz N| title=Diagnosis and treatment of urticaria in primary care. | journal=North Clin Istanb | year= 2019 | volume= 6 | issue= 1 | pages= 93-99 | pmid=31180381 | doi=10.14744/nci.2018.75010 | pmc=6526977 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31180381  }} </ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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[[Category:Dermatology]]
[[Category:Dermatology]]
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[[Category:Needs causes]]
[[Category:Primary care]]
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Latest revision as of 04:12, 28 January 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]

Overview

Urticaria may be caused idiopathically or due to immunological disorders such as autoimmune diseases, food allergies, medications and specific infections. There are also some non-immunological causes for urticaria development, such as physical triggers, dietary pseudo-allergen and hereditary urticaria.

Causes

Common Causes

Common causes of urticaria may include:[1][2][3][4]


 
 
 
 
The items:

High frequency of cross-reactivity, such as avocado, banana and chestnut
Moderate frequency of cross-reactivity such as apple, carrot, celery, kiwi, melon, papaya, potato and tomato
Low frequency of cross-reactivity, such as apricot, cherry, fig, grape, hazelnut, mango, nectarine, passion fruit, peach, peanut, pear, plum, pineapple, soybean, strawberry and walnut.

 
 
 
 


References

  1. 1.0 1.1 1.2 Deacock SJ (2008). "An approach to the patient with urticaria". Clin Exp Immunol. 153 (2): 151–61. doi:10.1111/j.1365-2249.2008.03693.x. PMC 2492902. PMID 18713139.
  2. Erben AM, Rodriguez JL, McCullough J, Ownby DR (1993). "Anaphylaxis after ingestion of beignets contaminated with Dermatophagoides farinae". J Allergy Clin Immunol. 92 (6): 846–9. doi:10.1016/0091-6749(93)90062-k. PMID 8258619.
  3. Beezhold DH, Sussman GL, Liss GM, Chang NS (1996). "Latex allergy can induce clinical reactions to specific foods". Clin Exp Allergy. 26 (4): 416–22. PMID 8732238.
  4. 4.0 4.1 4.2 4.3 4.4 Kayiran MA, Akdeniz N (2019). "Diagnosis and treatment of urticaria in primary care". North Clin Istanb. 6 (1): 93–99. doi:10.14744/nci.2018.75010. PMC 6526977 Check |pmc= value (help). PMID 31180381.
  5. Rajan JP, Simon RA, Bosso JV (2014). "Prevalence of sensitivity to food and drug additives in patients with chronic idiopathic urticaria". J Allergy Clin Immunol Pract. 2 (2): 168–71. doi:10.1016/j.jaip.2013.10.002. PMID 24607044.
  6. Wedi B, Kapp A (1999). "Helicobacter pylori infection and skin diseases". J Physiol Pharmacol. 50 (5): 753–76. PMID 10695557.
  7. Akashi R, Ishiguro N, Shimizu S, Kawashima M (2011). "Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori". J Dermatol. 38 (8): 761–6. doi:10.1111/j.1346-8138.2010.01106.x. PMID 21352335.
  8. Karaman U, Sener S, Calık S, Saşmaz S (2011). "[Investigation of microsporidia in patients with acute and chronic urticaria]". Mikrobiyol Bul. 45 (1): 168–73. PMID 21341171.
  9. 9.0 9.1 Zuberbier T (2003). "Urticaria". Allergy. 58 (12): 1224–34. doi:10.1046/j.1398-9995.2003.00327.x. PMID 14616095.
  10. Ros AM, Juhlin L, Michaëlsson G (1976). "A follow-up study of patients with recurrent urticaria and hypersensitivity to aspirin, benzoates and azo dyes". Br J Dermatol. 95 (1): 19–24. doi:10.1111/j.1365-2133.1976.tb15532.x. PMID 952737.
  11. Morrow JD, Margolies GR, Rowland J, Roberts LJ (1991). "Evidence that histamine is the causative toxin of scombroid-fish poisoning". N Engl J Med. 324 (11): 716–20. doi:10.1056/NEJM199103143241102. PMID 1997836.
  12. Zuberbier T, Iffländer J, Semmler C, Henz BM (1996). "Acute urticaria: clinical aspects and therapeutic responsiveness". Acta Derm Venereol. 76 (4): 295–7. doi:10.2340/0001555576295297. PMID 8869688.
  13. Soter NA, Joshi NP, Twarog FJ, Zeiger RS, Rothman PM, Colten HR (1977). "Delayed cold-induced urticaria: a dominantly inherited disorder". J Allergy Clin Immunol. 59 (4): 294–7. doi:10.1016/0091-6749(77)90050-1. PMID 66242.
  14. Staubach P, Dechene M, Metz M, Magerl M, Siebenhaar F, Weller K; et al. (2011). "High prevalence of mental disorders and emotional distress in patients with chronic spontaneous urticaria". Acta Derm Venereol. 91 (5): 557–61. doi:10.2340/00015555-1109. PMID 21597672.

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