Renal tubular acidosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Common risk factors in the development of renal tubular acidosis include urinary tract obstruction, diabetes mellitus, primary biliary cirrhosis, nephrocalcinosis, nephrolithiasis, Amphotericin-B therapy, cisplatinum, Untreated adrenal insufficiency.
Risk factors
Common risk factors in the development of renal tubular acidosis include:[1][2][3][4]
- Urinary tract obstruction
- Diabetes mellitus
- Primary biliary cirrhosis
- Nephrocalcinosis
- Nephrolithiasis
- Amphotericin-B therapy
- Cisplatinum
- Untreated adrenal insufficiency
- Family history
- Hereditary fructose intolerance
- Wilson disease
- Galactosemia
- Disorders of mitochondrial metabolism
- Glycogen storage diseases
- Tyrosinemia
- Lowe syndrome
- Cadmium
- Ifosfamide therapy
- Cystinosis
- Antiviral therapy (cidofovir, adefovir, or tenofovir)
Less Common Risk Factors
Less common risk factors in the development of renal tubular acidosis include:
- Cyclosporine therapy
- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blocking drugs
- Heparin therapy
- Medications interfering with sodium transport
- Use of carbonic anhydrase inhibitors
- Abnormalities of filtered immunoglobulins
- Interstitial nephritis
- Hyperparathyroidism
- Thai or southeast Asian ancestry
- Outdated tetracycline
- Balkan heritage
References
- ↑ Malik SI, Naqvi R, Ahmed E, Zafar MN (January 2011). "Prevalence and risk factors of renal tubular acidosis after kidney transplantation". J Pak Med Assoc. 61 (1): 23–7. PMID 22368897.
- ↑ Uribarri J, Oh MS, Pak CY (June 1994). "Renal stone risk factors in patients with type IV renal tubular acidosis". Am. J. Kidney Dis. 23 (6): 784–7. PMID 8203358.
- ↑ Caruana RJ, Buckalew VM (March 1988). "The syndrome of distal (type 1) renal tubular acidosis. Clinical and laboratory findings in 58 cases". Medicine (Baltimore). 67 (2): 84–99. PMID 3127650.
- ↑ Donnelly S, Kamel KS, Vasuvattakul S, Narins RG, Halperin ML (March 1992). "Might distal renal tubular acidosis be a proximal tubular cell disorder?". Am. J. Kidney Dis. 19 (3): 272–81. PMID 1553972.