Relapsing fever history and symptoms

Jump to navigation Jump to search

Relapsing fever Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Relapsing fever from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Relapsing fever history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Relapsing fever history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Relapsing fever history and symptoms

CDC on Relapsing fever history and symptoms

Relapsing fever history and symptoms in the news

Blogs on Relapsing fever history and symptoms

Directions to Hospitals Treating Relapsing fever

Risk calculators and risk factors for Relapsing fever history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The symptoms of relapsing fever present 3-7 days (up to 18 days) after exposure with sudden onset of high fever, chills, headache, myalgias, and weakness. Less common symptoms include anorexia, nausea, vomiting, abdominal pain, arthralgias, neck pain or back pain, confusion, lethargy, cough, rash, sore throat, and swollen lymph nodes.If left untreated, rapid defervescence usually occurs in 2-6 days (range 1-13 days), often with dramatic improvement in symptoms. Most cases eventually resolve spontaneously.The clinical manifestations of tick-borne and louse-borne relapsing fever are similar but can be quite variable, depending on the infecting strain of Borrelia and the host's immunity.

History and Symptoms

The clinical manifestations of tick-borne and louse-borne relapsing fever are similar but can be quite variable, depending on the infecting strain of Borrelia and the host's immunity. Patients typically present 3-7 days (up to 18 days) after exposure with sudden onset of high fever, chills, headache, myalgias, and weakness.

Incubation period = time from tick bite to illness

  • 7 days, range 2 to 18 days

Symptomatic period= Length of illness = time from symptom onset to resolution of symptoms

  • 3 days, range 2 to 7 days
  • In LBRF, the fever usually lasts 3-6 days and is usually followed by a single, milder episode. In TRBF, multiple episodes of fever occur, and each may last up to 3 days.

Number of relapses = number of episodes of reoccurring/relapsing symptoms

  • 3 times, can occur up to 10 times in persons who are not treated. Most cases eventually resolve spontaneously.
  • Patients with louse-borne relapsing fever will typically have 1-2 relapses (range 0-6) with each subsequent relapse usually less severe than the previous one.
  • Patients with tick-borne relapsing fever usually have 3-5 relapses (range 0-22).

Afebrile period= Length of time before reoccurrence = time from the resolution of symptoms to reoccurrence of symptoms

  • 7 days, range 4 to 14 days

Crisis

  • AS mentioned before, most cases eventually resolve spontaneously. Occasionally, the crisis occurs after the resolution, which is a classic series of stages that a person will go through:
  • 1. Phase one is the chill phase, with the person experiencing high fevers up to 41.5°C (106.7°F). With this high temperature, a person can develop delirium, agitation, and confusion. In addition, other signs of an increased metabolic rate are noted, such as a fast heart rate and breathing rate. This phase lasts between 10 and 30 minutes.
  • 2. Phase two is the flush phase. This is where the body temperature decreases rapidly, and the person has drenching sweats. During this phase, the person's blood pressure can drop dramatically[1]
  • During the crisis, patients may develop cerebral edema with seizures, cardiac failure, or death. This stage may result in death in up to 10% of patients.

Common symptoms

Less common symptoms

References