Milk-alkali syndrome primary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Effective measures for the primary prevention of milk-alkali syndrome include public education about the potential adverse effects of calcium supplements. Calcium intake less than 2 g/daily is usually safe, however, 1.2 to 1.5 g/daily of calcium intake should be taken by individuals with risk factors for milk-alkali syndrome.
Primary prevention
Effective measures for the primary prevention of milk-alkali syndrome include:[1][2][3][4][5][6][7]
- Public education about the potential adverse effects of calcium supplements due to its wide use with the awareness of osteoporosis prevention is important.
- Calcium intake less than 2 g/daily is usually safe.
- However, 1.2 to 1.5 g/daily of calcium intake should be taken by individuals with risk factors for milk-alkali syndrome, such as elderly, preexisting chronic renal disease, concurrent vomiting (bulimia nervosa or hyperemesis gravidarum ) and use of certain drugs like thiazide, NSAIDs, and ACE inhibitors.
References
- ↑ Medarov BI (2009). "Milk-alkali syndrome". Mayo Clin Proc. 84 (3): 261–7. doi:10.1016/S0025-6196(11)61144-0. PMC 2664604. PMID 19252114.
- ↑ Beall DP, Scofield RH (1995). "Milk-alkali syndrome associated with calcium carbonate consumption. Report of 7 patients with parathyroid hormone levels and an estimate of prevalence among patients hospitalized with hypercalcemia". Medicine (Baltimore). 74 (2): 89–96. doi:10.1097/00005792-199503000-00004. PMID 7891547.
- ↑ Whiting SJ, Wood R, Kim K (1997). "Calcium supplementation". J Am Acad Nurse Pract. 9 (4): 187–92. PMID 9274239.
- ↑ Patel AM, Goldfarb S (2010). "Got calcium? Welcome to the calcium-alkali syndrome". J Am Soc Nephrol. 21 (9): 1440–3. doi:10.1681/ASN.2010030255. PMID 20413609.
- ↑ Felsenfeld AJ, Levine BS (2006). "Milk alkali syndrome and the dynamics of calcium homeostasis". Clin J Am Soc Nephrol. 1 (4): 641–54. doi:10.2215/CJN.01451005. PMID 17699269.
- ↑ Picolos MK, Lavis VR, Orlander PR (2005). "Milk-alkali syndrome is a major cause of hypercalcaemia among non-end-stage renal disease (non-ESRD) inpatients". Clin Endocrinol (Oxf). 63 (5): 566–76. doi:10.1111/j.1365-2265.2005.02383.x. PMID 16268810.
- ↑ Arroyo M, Fenves AZ, Emmett M (2013). "The calcium-alkali syndrome". Proc (Bayl Univ Med Cent). 26 (2): 179–81. doi:10.1080/08998280.2013.11928954. PMC 3603742. PMID 23543983.