Eisenmenger’s syndrome laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]
Overview
The laboratory findings of patients with Eisenmenger's syndrome include erythrocytosis, iron deficiency, increased bleeding time, increased blood uric acid and conjugated bilirubin concentrations, as well as mixed respiratory and metabolic acidosis.
Laboratory Findings
The following may be observed on the laboratory work-up of patients with Eisenmenger's syndrome[1][2][3]:
- Erythrocytosis (increased Hb, Hct, and red blood cell mass)
- Iron deficiency (due to phlebotomy: reduced serum ferritin and increased iron binding capacity)
- Increased bleeding time (due to platelet dysfunction)
- Increased blood uric acid concentrations
- Increased conjugated bilirubin levels
- ABG: Mixed respiratory and metabolic acidosis.
- Brain natriuretic peptide: Elevated levels indicate poor prognosis.
References
- ↑ Vongpatanasin W, Brickner ME, Hillis LD, Lange RA (1998). "The Eisenmenger syndrome in adults". Ann Intern Med. 128 (9): 745–55. doi:10.7326/0003-4819-128-9-199805010-00008. PMID 9556469.
- ↑ An HS, Kim GB, Song MK, Bang JS, Lee SY, Bae EJ; et al. (2019). "Eisenmenger Syndrome in Adults: Treatment Pattern and Prognostic Factors in the Advanced Pulmonary Vasodilator Era". Pediatr Cardiol. 40 (1): 23–28. doi:10.1007/s00246-018-1956-y. PMID 30121863.
- ↑ Diller GP, Alonso-Gonzalez R, Kempny A, Dimopoulos K, Inuzuka R, Giannakoulas G; et al. (2012). "B-type natriuretic peptide concentrations in contemporary Eisenmenger syndrome patients: predictive value and response to disease targeting therapy". Heart. 98 (9): 736–42. doi:10.1136/heartjnl-2011-301522. PMID 22397941.