Complement component 9

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complement component 9
Identifiers
SymbolC9
Entrez735
HUGO1358
OMIM120940
RefSeqNM_001737
UniProtP02748
Other data
LocusChr. 5 p13

Complement component 9 (C9) is a protein involved in the complement system, which is part of the innate immune system.[1] C9 is a member of the complement membrane attack complex (MAC) and induces pores on cell membranes, causing lysis. There are 10-16 molecules of C9 in a single membrane attack complex (MAC), along with one of each of the complement components C5b, C6, C7 and C8.[2]

References

  1. Lint TF, Zeitz HJ, Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. PMID 7430628.
  2. Janeway, CA Jr; Travers P; Walport M; et al. (2001). "The complement system and innate immunity". Immunobiology: The Immune System in Health and Disease. New York: Garland Science. Retrieved 29 December 2017.

External links



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