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== Causes ==
== Causes ==


'''Typhoid fever''', also known as '''enteric fever''' and '''Salmonella typhi infection''', is an illness caused by the [[bacterium]] [[Salmonella enterica Serovar Typhi]] Common worldwide, it is transmitted by the [[fecal-oral route]] the ingestion of food or water contaminated with feces from an infected person. Flying insects feeding on feces may occasionally transfer the bacteria through poor hygiene habits and public sanitation conditions. It may surprise you, but what you eat and drink when you travel is a major risk factor. Raw vegetables and fruits that cannot be peeled also are the risk for causing typhoid fever.
*Typhoid fever is caused by ''[[Salmonella enterica]]'' serotype Typhi ([[Salmonella Typhi]])<ref name="pmid24901439">{{cite journal| author=Arndt MB, Mosites EM, Tian M, Forouzanfar MH, Mokhdad AH, Meller M et al.| title=Estimating the burden of paratyphoid a in Asia and Africa. | journal=PLoS Negl Trop Dis | year= 2014 | volume= 8 | issue= 6 | pages= e2925 | pmid=24901439 | doi=10.1371/journal.pntd.0002925 | pmc=4046978 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24901439  }} </ref><ref name="pmid16586383">{{cite journal| author=Maskey AP, Day JN, Phung QT, Thwaites GE, Campbell JI, Zimmerman M et al.| title=Salmonella enterica serovar Paratyphi A and S. enterica serovar Typhi cause indistinguishable clinical syndromes in Kathmandu, Nepal. | journal=Clin Infect Dis | year= 2006 | volume= 42 | issue= 9 | pages= 1247-53 | pmid=16586383 | doi=10.1086/503033 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16586383  }} </ref>
<ref name="pmid7499779">{{cite journal| author=Oboegbulam SI, Oguike JU, Gugnani HC| title=Microbiological studies on cases diagnosed as typhoid/enteric fever in south-east Nigeria. | journal=J Commun Dis | year= 1995 | volume= 27 | issue= 2 | pages= 97-100 | pmid=7499779 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7499779  }} </ref><ref name="pmid15837356">{{cite journal| author=Vollaard AM, Ali S, Widjaja S, Asten HA, Visser LG, Surjadi C et al.| title=Identification of typhoid fever and paratyphoid fever cases at presentation in outpatient clinics in Jakarta, Indonesia. | journal=Trans R Soc Trop Med Hyg | year= 2005 | volume= 99 | issue= 6 | pages= 440-50 | pmid=15837356 | doi=10.1016/j.trstmh.2004.09.012 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15837356  }} </ref><ref name="pmid25458731">{{cite journal| author=Wain J, Hendriksen RS, Mikoleit ML, Keddy KH, Ochiai RL| title=Typhoid fever. | journal=Lancet | year= 2015 | volume= 385 | issue= 9973 | pages= 1136-45 | pmid=25458731 | doi=10.1016/S0140-6736(13)62708-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25458731  }} </ref><ref>http://www.cdc.gov/typhoid-fever/health-professional.html</ref>
[[Image:1024px-SalmonellaNIAID.jpg|thumb|Salmonella Typhi|200px|right|Samonella Typhi]]
*'''Serovars'''
Other Salmonellae which may cause similar symptoms include
 
**''Salmonella Paratyphi A''
**''Salmonella Paratyphi B''
**''Salmonella Paratyphi C''
**''Salmonella choleraesuis''
 
*'''Features of Salmonella Typhi'''<ref> Fàbrega, Anna, and Jordi Vila. "Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation." Clinical microbiology reviews 26.2 (2013): 308-341.</ref>
**Gram negative bacillus
**Flagellated
**Facultatively anaerobic
**Three [[antigens]] O,H and Vi
**Belongs to [[Enterobacteriaceae]] family
**Chemotroph


== References ==
== References ==

Revision as of 15:00, 25 August 2016


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Causes

[3][4][5][6]

Samonella Typhi
  • Serovars

Other Salmonellae which may cause similar symptoms include

    • Salmonella Paratyphi A
    • Salmonella Paratyphi B
    • Salmonella Paratyphi C
    • Salmonella choleraesuis
  • Features of Salmonella Typhi[7]
    • Gram negative bacillus
    • Flagellated
    • Facultatively anaerobic
    • Three antigens O,H and Vi
    • Belongs to Enterobacteriaceae family
    • Chemotroph

References

  1. Arndt MB, Mosites EM, Tian M, Forouzanfar MH, Mokhdad AH, Meller M; et al. (2014). "Estimating the burden of paratyphoid a in Asia and Africa". PLoS Negl Trop Dis. 8 (6): e2925. doi:10.1371/journal.pntd.0002925. PMC 4046978. PMID 24901439.
  2. Maskey AP, Day JN, Phung QT, Thwaites GE, Campbell JI, Zimmerman M; et al. (2006). "Salmonella enterica serovar Paratyphi A and S. enterica serovar Typhi cause indistinguishable clinical syndromes in Kathmandu, Nepal". Clin Infect Dis. 42 (9): 1247–53. doi:10.1086/503033. PMID 16586383.
  3. Oboegbulam SI, Oguike JU, Gugnani HC (1995). "Microbiological studies on cases diagnosed as typhoid/enteric fever in south-east Nigeria". J Commun Dis. 27 (2): 97–100. PMID 7499779.
  4. Vollaard AM, Ali S, Widjaja S, Asten HA, Visser LG, Surjadi C; et al. (2005). "Identification of typhoid fever and paratyphoid fever cases at presentation in outpatient clinics in Jakarta, Indonesia". Trans R Soc Trop Med Hyg. 99 (6): 440–50. doi:10.1016/j.trstmh.2004.09.012. PMID 15837356.
  5. Wain J, Hendriksen RS, Mikoleit ML, Keddy KH, Ochiai RL (2015). "Typhoid fever". Lancet. 385 (9973): 1136–45. doi:10.1016/S0140-6736(13)62708-7. PMID 25458731.
  6. http://www.cdc.gov/typhoid-fever/health-professional.html
  7. Fàbrega, Anna, and Jordi Vila. "Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation." Clinical microbiology reviews 26.2 (2013): 308-341.

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