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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
__NOTOC__
 
{{CMG}}
 
 
 
==Overview==
{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name        = {{PAGENAME}} |
   Name        = {{PAGENAME}} |
   ICD10      = {{ICD10|K|90|1|k|90}} |
   ICD10      = {{ICD10|K|90|1|k|90}} |
   ICD9        = {{ICD9|579.1}} |
   ICD9        = {{ICD9|579.1}} |
}}
DiseasesDB    = 13393 |
{{SI}}
  MedlinePlus = 000275 |}}
'''Tropical sprue''' is a [[malabsorption]] disease commonly found in the tropical regions, marked with abnormal flattening of the [[villi]] and [[inflammation]] of the lining of the [[small intestine]].
{{Tropical sprue}}
 
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


It differs significantly from [[coeliac sprue]].
{{CMG}}; {{AE}} {{AKI}}


==Symptoms==
{{SK}} Postinfective tropical malabsorption, Sprue
The symptoms of tropical sprue are:


* [[Diarrhoea]]
==[[Tropical sprue overview|Overview]]==
* [[Steatorrhea]] or foul-smelling faeces
* [[Indigestion]]
* [[Cramps]]
* [[Weight loss]] and [[malnutrition]]
* [[Fatigue (physical)|Fatigue]]


Left untreated, nutrient and [[vitamin deficiency| vitamin deficiencies]] may develop in patients with tropical sprue.  These deficiencies may have the following symptoms:
==[[Tropical sprue historical perspective|Historical Perspective]]==


* [[Vitamin A]] deficiency: [[hyperkeratosis]] or skin scales
==[[Tropical sprue classification|Classification]]==
* [[Vitamin B12]] and [[folic acid]] deficiencies: anaemia
* [[Vitamin D]] and [[calcium]] deficiencies: [[spasm]], [[bone pain]], [[numbness]] and [[tingling sensation]]
* [[Vitamin K]] deficiency: [[bruises]]


==Signs==
==[[Tropical sprue pathophysiology|Pathophysiology]]==


Diagnosis of tropical sprue can be complicated because many diseases have similar symptoms.  Your doctor would look for the following signs:
==[[Tropical sprue causes|Causes]]==


* Abnormal flattening of [[villi]] and inflammation of the lining of the small intestine, observed during an [[endoscopy|endoscopic]] procedure.
==[[Tropical sprue differential diagnosis|Differentiating Tropical sprue from other Diseases]]==
* Presence of inflammatory cell in the [[biopsy]] of small intestine tissue.
* Low levels of vitamins [[vitamin A|A]], [[vitamin B12|B12]], [[vitamin E|E]], [[vitamin D|D]], and [[vitamin K|K]], as well as [[serum albumin]], [[calcium]], and [[folate]], revealed by a blood test.
* Excess fat in the [[feces]] (steatorrhoea).


Tropical sprue is largely limited to within about 30 degrees north and south of the equator. Therefore, if one resides outside of that geographical region, recent travel to the region is a key factor in diagnosing this disease.
==[[Tropical sprue epidemiology and demographics|Epidemiology and Demographics]]==


==Cause==
==[[Tropical sprue risk factors|Risk Factors]]==
The cause of tropical sprue is not known.  It has been suggested that it is caused by bacterial, viral, amoebal, or parasitic infection.  Folic acid deficiency and rancid fat have also been suggested as possible causes.


In a condition called coeliac disease (also known as ''[[coeliac sprue]]''), which has similar symptoms (to tropical sprue), the flattening of the villi and small intestine inflammation is caused by an [[autoimmune disorder]].
==[[Tropical sprue screening|Screening]]==


==Affected Regions==
==[[Tropical sprue natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


The disease was first described by William Hillary in 1759 in Barbados. Tropical sprue is endemic to India and southeast Asia, Central and South America, and the Caribbean.
==Diagnosis==
[[Tropical sprue history and symptoms|History and Symptoms]] | [[Tropical sprue physical examination|Physical Examination]] | [[Tropical sprue laboratory findings|Laboratory Findings]]  | [[Tropical sprue electrocardiogram|Electrocardiogram]] | [[Tropical sprue x ray|X Ray]] | [[Tropical sprue CT|CT]] | [[Tropical sprue MRI|MRI]] | [[Tropical sprue ultrasound|Ultrasound]] | [[Tropical sprue other imaging findings|Other Imaging Findings]] | [[Tropical sprue other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
Once diagnosed, tropical sprue can be treated by a course of the antibiotic [[tetracycline]] and vitamins B12 and folic acid for at least 6 months.
[[Tropical sprue medical therapy|Medical Therapy]] | [[Tropical sprue surgery|Surgery]] | [[Tropical sprue primary prevention|Primary Prevention]] | [[Tropical sprue secondary prevention|Secondary Prevention]] | [[Tropical sprue cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Tropical sprue future or investigational therapies|Future or Investigational Therapies]]  


==Prevention==
==Case Studies==
 
[[Tropical sprue case study one|Case #1]]
Preventions of tropical sprue include avoiding travel to the affected regions.
 
If you have to travel, remember to use only bottled water for drinking, brushing teeth, and washing food.  Do not eat fruits that have been washed with tap water or limit yourself to fruits that can be peeled, such as banana and oranges.
 
==Prognosis==
The prognosis for tropical sprue is excellent.  It usually does not recur in patients who get it during travel to affected regions.  The recurrence rate for natives is about 20%.
 
==External links==
 
* [http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10902.html InteliHealth - Tropical Sprue]
* {{eMedicine|med|2162|Sprue, Tropical}}
* [http://www.healthinplainenglish.com/health/digestive/tropical_sprue/index.htm Health In Plain English - Tropical Sprue]
* [http://www.merck.com/mrkshared/mmanual/section3/chapter30/30d.jsp Merck Manual - Malabsorption Syndromes: Tropical Sprue]
* {{MedlinePlus|000275|Tropical sprue}}
* {{DiseasesDB|13393}}
 
 
{{Gastroenterology}}
 
[[Category:Ailments of unknown etiology]]
[[Category:Gastroenterology]]
[[Category:Malnutrition]]


[[es:Esprue tropical]]
[[es:Esprue tropical]]
[[nl:Tropische spruw]]
[[nl:Tropische spruw]]
[[pl:Sprue tropikalna]]
[[pl:Sprue tropikalna]]
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[[Category:Gastroenterology]]
[[Category:Infectious Disease]]
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[[Category:Infectious disease]]

Latest revision as of 00:29, 30 July 2020

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Tropical sprue Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tropical sprue from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

Synonyms and keywords: Postinfective tropical malabsorption, Sprue

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tropical sprue from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1 nl:Tropische spruw


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