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{{Transposition of the great vessels}}
__NOTOC__
'''For the WikiDoc page for this topic, click [[Transposition of the great vessels|here]]'''
{{Transposition of the great vessels (patient information)}}
'''For the WikiDoc page for this topic, click [[Transposition of the great vessels]]'''


{{CMG}}; '''Associate Editors-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, MBBS]] [[mailto:psingh@perfuse.org]]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu];  Claudia Hochberg, M.D.; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [[mailto:kfeeney@perfuse.org]]
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu]; '''Assistant Editor(s)-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu]


__NOTOC__
==Overview==
==Overview==
Transposition of the great vessels is a congenital heart defect in which the two major vessels that carry blood away from the heart the aorta and the pulmonary artery are switched (transposed).
Transposition of the great vessels is a congenital heart defect in which the two major vessels that carry blood away from the heart the aorta and the pulmonary artery are switched (transposed).
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==What causes Transposition of the great vessels?==
==What causes Transposition of the great vessels?==
The cause of most congenital heart defects is unknown.
The cause of most congenital heart defects is unknown.
Transposition of the great vessels is a cyanotic heart defect. This means there is decreased oxygen in the blood that is pumped from the heart to the rest of the body. Low blood oxygen leads to cyanosis (a bluish-purple color to the skin) and shortness of breath.
In normal hearts, blood that returns from the body goes through the right side of the heart and pulmonary artery to the lungs to get oxygen. The blood then comes back to the left side of the heart and travels out the aorta to the body.
In transposition of the great vessels, the blood goes to the lungs, picks up oxygen, and then goes right back to the lungs without ever going to the body. Blood from the body returns to the heart and goes back to the body without ever picking up oxygen in the lungs.
Symptoms appear at birth or very soon afterward. How bad the symptoms are depends on the type and size of heart defects (such as atrial septal defect or patent ductus arteriosus) and how much oxygen moves through the body's general blood flow.
The condition is the second most common cyanotic heart defect.
==Who is at highest risk?==
Factors in the mother that may increase the risk of this condition include:
Factors in the mother that may increase the risk of this condition include:
* Age over 40
* Age over 40
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* Rubella or other viral illness during pregnancy
* Rubella or other viral illness during pregnancy


Transposition of the great vessels is a cyanotic heart defect. This means there is decreased oxygen in the blood that is pumped from the heart to the rest of the body. Low blood oxygen leads to cyanosis (a bluish-purple color to the skin) and shortness of breath.
==When to seek urgent medical care?==
In normal hearts, blood that returns from the body goes through the right side of the heart and pulmonary artery to the lungs to get oxygen. The blood then comes back to the left side of the heart and travels out the aorta to the body.
Most often, this condition is diagnosed during routine examination. This condition can also be diagnosed before birth using a fetal echocardiogram. If not, it is usually diagnosed soon after a baby is born. Call your infant's health care provider if the baby seems to be having difficulty breathing, if your baby's skin develops a bluish color, especially in the face or trunk. or if the baby seems to have an unusual number of respiratory infections.
In transposition of the great vessels, the blood goes to the lungs, picks up oxygen, and then goes right back to the lungs without ever going to the body. Blood from the body returns to the heart and goes back to the body without ever picking up oxygen in the lungs.
Symptoms appear at birth or very soon afterward. How bad the symptoms are depends on the type and size of heart defects (such as atrial septal defect or patent ductus arteriosus) and how much oxygen moves through the body's general blood flow.
 
The condition is the second most common cyanotic heart defect.


==Possible Complications?==
Contact your health care provider if your baby has this condition and new symptoms develop, get worse, or continue after treatment.
* Arrhythmias
* Coronary artery problems
* Heart valve problems


==Exams and Tests==
==Diagnosis==
The health care provider may detect a heart murmur while listening to the chest with a stethoscope. The baby's mouth and skin will be a blue color.
The health care provider may detect a heart murmur while listening to the chest with a stethoscope. The baby's mouth and skin will be a blue color.
Tests often include the following:
Tests often include the following:
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A surgery called an arterial switch procedure is used to permanently correct the problem within the baby's first week of life. This surgery switches the great arteries back to the normal position and keeps the coronary arteries attached to the aorta.
A surgery called an arterial switch procedure is used to permanently correct the problem within the baby's first week of life. This surgery switches the great arteries back to the normal position and keeps the coronary arteries attached to the aorta.


==When to Contact a Medical Professional?==
==Where to find medical care for Transpostion of the great vessels?==
Most often, this condition is diagnosed during routine examination of an infant. Call your infant's health care provider if the baby seems to be having difficulty breathing, or if the baby seems to have an unusual number of respiratory infections.
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Transposition of the great vessels}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Transposition of the great vessels]


==Outlook (Prognosis)==
==What to expect (Outlook/Prognosis)?==
The child's symptoms will improve after surgery to correct the defect. Most infants who undergo arterial switch do not have symptoms after surgery and live normal lives. If corrective surgery is not performed, the life expectancy is months.
The child's symptoms will improve after surgery to correct the defect. Most infants who undergo arterial switch do not have symptoms after surgery and live normal lives. If corrective surgery is not performed, the life expectancy is months.
==Possible Complications==
* Arrhythmias
* Coronary artery problems
* Heart valve problems


==Prevention==
==Prevention==
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Drinking alcohol and using the antiseizure medicines depakote and dilantin during pregnancy have been associated with increased incidence of VSDs. Other than avoiding these things during pregnancy, there is no known way to prevent a VSD.
Drinking alcohol and using the antiseizure medicines depakote and dilantin during pregnancy have been associated with increased incidence of VSDs. Other than avoiding these things during pregnancy, there is no known way to prevent a VSD.


== When to contact health professional?==
{{#ev:youtube|2ddxXHQzWF8}}
This condition can be diagnosed before birth using a fetal echocardiogram. If not, it is usually diagnosed soon after a baby is born.
Go to the emergency room or call the local emergency number (such as 911) if your baby's skin develops a bluish color, especially in the face or trunk.
Call your health care provider if your baby has this condition and new symptoms develop, get worse, or continue after treatment.
 
<youtube v=2ddxXHQzWF8/>


==Sources==
==Sources==
http://www.nlm.nih.gov/medlineplus/ency/article/001568.htm
http://www.nlm.nih.gov/medlineplus/ency/article/001568.htm
{{Reflist|2}}
{{Congenital malformations and deformations of circulatory system}}
{{SIB}}


[[de:Herzfehler]]
[[es:Cardiopatía congénita]]
[[es:Cardiopatía congénita]]
[[fr:Cardiopathie congénitale]]
[[fr:Cardiopathie congénitale]]
[[lv:Iedzimtās sirds slimības]]
[[nn:Medfødd hjartefeil]]
[[pl:Wada serca]]
[[pt:Cardiopatia congênita]]
[[pt:Cardiopatia congênita]]
[[sr:Урођене срчане мане]]
{{WH}}
[[uk:Вроджені вади серця]]
{{WS}}
[[wa:Maladeye des bleus påpåds]]
[[tr:Doğumsal kalp hastalıkları]]


[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Congenital heart disease]]
[[Category:Congenital heart disease]]
[[Category:Genetic disease]]
[[Category:Cardiology patient information]]
[[Category:Cardiology patient information]]
[[Category:Congenital heart disease patient information]]
[[Category:Congenital heart disease patient information]]
[[Category:Pediatrics patient information]]
[[Category:Pediatrics patient information]]
[[Category:Patient information]]
[[Category:Patient information]]
[[Category:Overview complete]]
[[Category:Template complete]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
 
[[Category:Disease]]
{{WH}}
{{WS}}

Latest revision as of 18:36, 2 November 2012

Transposition of the great vessels

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

When to seek urgent medical care?

Diagnosis

Treatment options

Diseases with similar symptoms

Where to find medical care for Transposition of the great vessels?

What to expect (Outlook/Prognosis)?

Possible complications

Prevention

Transposition of the great vessels On the Web

Ongoing Trials at Clinical Trials.gov

Images of Transposition of the great vessels

Videos on Transposition of the great vessels

FDA on Transposition of the great vessels

CDC on Transposition of the great vessels

Transposition of the great vessels in the news

Blogs on Transposition of the great vessels

Directions to Hospitals Treating Transposition of the great vessels

Risk calculators and risk factors for Transposition of the great vessels

For the WikiDoc page for this topic, click Transposition of the great vessels

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

Transposition of the great vessels is a congenital heart defect in which the two major vessels that carry blood away from the heart the aorta and the pulmonary artery are switched (transposed).

What are the symptoms of Transposition of the great vessels?

  • Blueness of the skin
  • Clubbing of the fingers or toes
  • Poor feeding
  • Shortness of breath

What causes Transposition of the great vessels?

The cause of most congenital heart defects is unknown.

Transposition of the great vessels is a cyanotic heart defect. This means there is decreased oxygen in the blood that is pumped from the heart to the rest of the body. Low blood oxygen leads to cyanosis (a bluish-purple color to the skin) and shortness of breath. In normal hearts, blood that returns from the body goes through the right side of the heart and pulmonary artery to the lungs to get oxygen. The blood then comes back to the left side of the heart and travels out the aorta to the body. In transposition of the great vessels, the blood goes to the lungs, picks up oxygen, and then goes right back to the lungs without ever going to the body. Blood from the body returns to the heart and goes back to the body without ever picking up oxygen in the lungs. Symptoms appear at birth or very soon afterward. How bad the symptoms are depends on the type and size of heart defects (such as atrial septal defect or patent ductus arteriosus) and how much oxygen moves through the body's general blood flow.

The condition is the second most common cyanotic heart defect.

Who is at highest risk?

Factors in the mother that may increase the risk of this condition include:

  • Age over 40
  • Alcoholism
  • Diabetes
  • Poor nutrition during pregnancy (prenatal nutrition)
  • Rubella or other viral illness during pregnancy

When to seek urgent medical care?

Most often, this condition is diagnosed during routine examination. This condition can also be diagnosed before birth using a fetal echocardiogram. If not, it is usually diagnosed soon after a baby is born. Call your infant's health care provider if the baby seems to be having difficulty breathing, if your baby's skin develops a bluish color, especially in the face or trunk. or if the baby seems to have an unusual number of respiratory infections.

Contact your health care provider if your baby has this condition and new symptoms develop, get worse, or continue after treatment.

Diagnosis

The health care provider may detect a heart murmur while listening to the chest with a stethoscope. The baby's mouth and skin will be a blue color. Tests often include the following:

  • Cardiac catheterization
  • Chest x-ray
  • ECG
  • Echocardiogram (if done before birth, it is called a fetal echocardiogram)
  • Pulse oximetry (to check blood oxygen level)

Treatment options

The baby will immediately receive a medicine called prostaglandin through an IV (intravenous line). This medicine helps keep the ductus arteriosus open, allowing some mixing of the two blood circulations. A procedure using cardiac catheterization (balloon atrial septostomy) may be needed to create a large hole in the atrial septum to allow blood to mix. A surgery called an arterial switch procedure is used to permanently correct the problem within the baby's first week of life. This surgery switches the great arteries back to the normal position and keeps the coronary arteries attached to the aorta.

Where to find medical care for Transpostion of the great vessels?

Directions to Hospitals Treating Transposition of the great vessels

What to expect (Outlook/Prognosis)?

The child's symptoms will improve after surgery to correct the defect. Most infants who undergo arterial switch do not have symptoms after surgery and live normal lives. If corrective surgery is not performed, the life expectancy is months.

Possible Complications

  • Arrhythmias
  • Coronary artery problems
  • Heart valve problems

Prevention

Except for the case of heart-attack-associated VSD, this condition is always present at birth. Drinking alcohol and using the antiseizure medicines depakote and dilantin during pregnancy have been associated with increased incidence of VSDs. Other than avoiding these things during pregnancy, there is no known way to prevent a VSD.

{{#ev:youtube|2ddxXHQzWF8}}

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/001568.htm Template:WH Template:WS