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| __NOTOC__ | | __NOTOC__ |
| {{Toxic shock syndrome}} | | {{Toxic shock syndrome}} |
| {{CMG}}; {{AE}} | | {{CMG}}; {{AE}}{{HK}} |
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| ==Overview== | | ==Overview== |
| Mainstay of screening for toxic shock syndrome (TSS) is patient education and awareness of the symptoms. Other tests which can be used as a tool to detect the toxic shock syndrome toxin 1 (TSST-1) in patient's blood include the latex agglutination method, and competitive agglutination inhibition assay.
| | There is insufficient evidence to recommend routine screening for toxic shock syndrome. |
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| ==Screening== | | ==Screening== |
| * Patient education remains a primary key to screening and prevention. Patients should be aware of the symptoms of toxic shock syndrome and, if symptoms occur, they should seek medical attention immediately. <ref name="pmid1328970">{{cite journal |vauthors=Colbry SL |title=A review of toxic shock syndrome: the need for education still exists |journal=Nurse Pract |volume=17 |issue=9 |pages=39–40, 43, 46 |year=1992 |pmid=1328970 |doi= |url=}}</ref> | | *There is insufficient evidence to recommend routine screening for toxic shock syndrome. |
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| * Latex agglutination method, in which latex particles are sensitized with specific anti-toxic shock syndrome toxin-1 (TSST-1) immunoglobulin, has been found to be a simple and sensitive method for the detection of TSST-1 production by Staphylococcus aureus strains. <ref name="pmid3082921">{{cite journal |vauthors=Igarashi H, Fujikawa H, Shingaki M, Bergdoll MS |title=Latex agglutination test for staphylococcal toxic shock syndrome toxin 1 |journal=J. Clin. Microbiol. |volume=23 |issue=3 |pages=509–12 |year=1986 |pmid=3082921 |pmc=268684 |doi= |url=}}</ref> In order order to exclude other diseases with similar presentation, additional mandatory exclusionary laboratory data needs to be collected.
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| * Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay has been found to be a preliminary investigation for medical screening of suspected toxic shock syndrome and is applicable in situations where antibody assays are not routinely used for anti-TSST-1 and also where advanced medical equipment is not available.<ref name="pmid12753244">{{cite journal |vauthors=Javid Khojasteh V, Rogan MT, Edwards-Jones V, Foster HA |title=Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay |journal=Lett. Appl. Microbiol. |volume=36 |issue=6 |pages=372–6 |year=2003 |pmid=12753244 |doi= |url=}}</ref>
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| ==References== | | ==References== |
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| {{WH}} | | {{WH}} |
| {{WS}} | | {{WS}} |
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| | [[Category:Emergency mdicine]] |
| | [[Category:Disease]] |
| | [[Category:Up-To-Date]] |
| | [[Category:Infectious disease]] |