Thiamphenicol: Difference between revisions
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| routes_of_administration= [[Wiktionary:intravenous|IV]], [[Wiktionary:intramuscular|IM]], [[Wiktionary:oral|O]] }} | | routes_of_administration= [[Wiktionary:intravenous|IV]], [[Wiktionary:intramuscular|IM]], [[Wiktionary:oral|O]] }} | ||
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'''Thiamphenicol''' is an [[antibiotic]]. It is the [[methyl]]-[[sulfonyl]] analogue of [[chloramphenicol]] and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, is insoluble in water but highly soluble in [[lipid]]s. It is used in many countries as a [[veterinary]] antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with [[aplastic anaemia]]. | '''Thiamphenicol''' is an [[antibiotic]]. It is the [[methyl]]-[[sulfonyl]] analogue of [[chloramphenicol]] and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, is insoluble in water but highly soluble in [[lipid]]s. It is used in many countries as a [[veterinary]] antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with [[aplastic anaemia]]. | ||
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Revision as of 16:51, 20 August 2012
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| Clinical data | |
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| Pregnancy category |
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| Routes of administration | IV, IM, O |
| ATC code | |
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| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | hepatic |
| Elimination half-life | 5.0 hours |
| Excretion | renal |
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| PubChem CID | |
| DrugBank | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C12H15Cl2NO5S |
| Molar mass | 356.223 g/mol |
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WikiDoc Resources for Thiamphenicol |
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Most recent articles on Thiamphenicol Most cited articles on Thiamphenicol |
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Powerpoint slides on Thiamphenicol |
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Evidence Based Medicine |
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Ongoing Trials on Thiamphenicol at Clinical Trials.gov Trial results on Thiamphenicol Clinical Trials on Thiamphenicol at Google
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US National Guidelines Clearinghouse on Thiamphenicol NICE Guidance on Thiamphenicol
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Definitions |
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Patient Resources / Community |
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Patient resources on Thiamphenicol Discussion groups on Thiamphenicol Patient Handouts on Thiamphenicol Directions to Hospitals Treating Thiamphenicol Risk calculators and risk factors for Thiamphenicol
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Causes & Risk Factors for Thiamphenicol |
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Continuing Medical Education (CME) |
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Thiamphenicol is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, is insoluble in water but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Alternative names
- Dextrosulphenidol
- Thiophenicol
External links
- Overview at World Health Organization - Food and Agriculture Organization
- Raymond J, Boutros N, Bergeret M (2004). "Role of thiamphenicol in the treatment of community-acquired lung infections". Med Trop (Mars). 64 (1): 33–8. PMID 15224555.
- Marchese A, Debbia E, Tonoli E, Gualco L, Schito A (2002). "In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy". J Chemother. 14 (6): 554–61. PMID 12583545.
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- Antibiotics