TYRO3

TYRO3 protein tyrosine kinase
File:PBB Protein TYRO3 image.jpg PDB rendering based on 1rhf.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1rhf​
Identifiers
Symbols	TYRO3 ; BYK; Brt; Dtk; RSE; Sky; Tif
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4585
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TYRO3 211432 s at tn.png
File:PBB GE TYRO3 211431 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

TYRO3 protein tyrosine kinase, also known as TYRO3, is a human gene.

Further reading

• Mark MR, Scadden DT, Wang Z; et al. (1994). "rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain". J. Biol. Chem. 269 (14): 10720–8. PMID 7511603.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase". Biochem. Biophys. Res. Commun. 209 (2): 656–63. doi:10.1006/bbrc.1995.1549. PMID 7537495.CS1 maint: Multiple names: authors list (link)
• Richard I, Broux O, Chiannilkulchai N; et al. (1995). "Regional localization of human chromosome 15 loci". Genomics. 23 (3): 619–27. PMID 7851890.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Crosier KE, Hall LR, Lewis PM; et al. (1995). "Isolation and characterization of the human DTK receptor tyrosine kinase". Growth Factors. 11 (2): 137–44. PMID 7857658.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohashi K, Mizuno K, Kuma K; et al. (1994). "Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain". Oncogene. 9 (3): 699–705. PMID 8108112.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dai W, Pan H, Hassanain H; et al. (1994). "Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis". Oncogene. 9 (3): 975–9. PMID 8108143.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Polvi A, Armstrong E, Lai C; et al. (1994). "The human TYRO3 gene and pseudogene are located in chromosome 15q14-q25". Gene. 134 (2): 289–93. PMID 8262388.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mark MR, Chen J, Hammonds RG; et al. (1996). "Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl". J. Biol. Chem. 271 (16): 9785–9. PMID 8621659.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Crosier PS, Freeman SA, Orlic D; et al. (1996). "The Dtk receptor tyrosine kinase, which binds protein S, is expressed during hematopoiesis". Exp. Hematol. 24 (2): 318–23. PMID 8641360.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagata K, Ohashi K, Nakano T; et al. (1997). "Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases". J. Biol. Chem. 271 (47): 30022–7. PMID 8939948.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kajii Y, Ninomiya D, Kato M; et al. (1997). "A tyrosine kinase-like molecule is localized in the nuclear membrane of neurons: hippocampal behavior under stress". Biol. Cell. 88 (1–2): 45–54. PMID 9175267.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lan Z, Wu H, Li W; et al. (2000). "Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway". Blood. 95 (2): 633–8. PMID 10627473.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yin JL, Hambly BD, Bao SS; et al. (2004). "Expression of growth arrest-specific gene 6 and its receptors in dysfunctional human renal allografts". Transpl. Int. 16 (9): 681–8. doi:10.1007/s00147-003-0593-3. PMID 12768229.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heiring C, Dahlbäck B, Muller YA (2004). "Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family". J. Biol. Chem. 279 (8): 6952–8. doi:10.1074/jbc.M311750200. PMID 14623883.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gould WR, Baxi SM, Schroeder R; et al. (2005). "Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses". J. Thromb. Haemost. 3 (4): 733–41. doi:10.1111/j.1538-7836.2005.01186.x. PMID 15733062.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hafizi S, Gustafsson A, Stenhoff J, Dahlbäck B (2005). "The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases". Int. J. Biochem. Cell Biol. 37 (11): 2344–56. doi:10.1016/j.biocel.2005.05.006. PMID 15964779.CS1 maint: Multiple names: authors list (link)
• Shimojima M, Takada A, Ebihara H; et al. (2006). "Tyro3 family-mediated cell entry of Ebola and Marburg viruses". J. Virol. 80 (20): 10109–16. doi:10.1128/JVI.01157-06. PMID 17005688.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)