TPX2

TPX2, microtubule-associated, homolog (Xenopus laevis)
File:PBB Protein TPX2 image.jpg PDB rendering based on 1ol5.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1ol5​
Identifiers
Symbols	TPX2 ; p100; C20orf1; C20orf2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA519; HCTP4; REPP86
External IDs	Template:OMIM5 Template:MGI HomoloGene: 8107
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TPX2 210052 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

TPX2, microtubule-associated, homolog (Xenopus laevis), also known as TPX2, is a human gene.

Further reading

• Heidebrecht HJ, Buck F, Steinmann J; et al. (1997). "p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M.". Blood. 90 (1): 226–33. PMID 9207457.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang Y, Heidebrecht H, Rott A; et al. (1999). "Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization". Cytogenet. Cell Genet. 84 (3–4): 182–3. PMID 10393424.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Manda R, Kohno T, Matsuno Y; et al. (1999). "Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display". Genomics. 61 (1): 5–14. doi:10.1006/geno.1999.5939. PMID 10512675.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wittmann T, Wilm M, Karsenti E, Vernos I (2000). "TPX2, A novel xenopus MAP involved in spindle pole organization". J. Cell Biol. 149 (7): 1405–18. PMID 10871281.CS1 maint: Multiple names: authors list (link)
• Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang Y, Han KJ, Pang XW; et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. PMID 12097419.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kufer TA, Silljé HH, Körner R; et al. (2002). "Human TPX2 is required for targeting Aurora-A kinase to the spindle". J. Cell Biol. 158 (4): 617–23. doi:10.1083/jcb.200204155. PMID 12177045.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gruss OJ, Wittmann M, Yokoyama H; et al. (2004). "Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells". Nat. Cell Biol. 4 (11): 871–9. doi:10.1038/ncb870. PMID 12389033.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Garrett S, Auer K, Compton DA, Kapoor TM (2003). "hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division". Curr. Biol. 12 (23): 2055–9. PMID 12477396.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heidebrecht HJ, Adam-Klages S, Szczepanowski M; et al. (2004). "repp86: A human protein associated in the progression of mitosis". Mol. Cancer Res. 1 (4): 271–9. PMID 12612055.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bayliss R, Sardon T, Vernos I, Conti E (2003). "Structural basis of Aurora-A activation by TPX2 at the mitotic spindle". Mol. Cell. 12 (4): 851–62. PMID 14580337.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cassimeris L, Morabito J (2004). "TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly". Mol. Biol. Cell. 15 (4): 1580–90. doi:10.1091/mbc.E03-07-0544. PMID 14718566.
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maxwell CA, Keats JJ, Belch AR; et al. (2005). "Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity". Cancer Res. 65 (3): 850–60. PMID 15705883.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stewart S, Fang G (2005). "Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit". Mol. Cell. Biol. 25 (23): 10516–27. doi:10.1128/MCB.25.23.10516-10527.2005. PMID 16287863.
• Ma Y, Lin D, Sun W; et al. (2006). "Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer". Clin. Cancer Res. 12 (4): 1121–7. doi:10.1158/1078-0432.CCR-05-1766. PMID 16489064.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nousiainen M, Silljé HH, Sauer G; et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)