Syphilis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Sexually transmitted diseases Main Page
Syphilis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Syphilis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy Primary and Secondary Syphilis Latent Syphilis Tertiary Syphilis Neurosyphilis HIV-Infected Patients Pregnancy Management of Sexual Partners
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Syphilis classification On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Syphilis classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Syphilis classification
CDC on Syphilis classification
Syphilis classification in the news
Blogs on Syphilis classification
Directions to Hospitals Treating Syphilis
Risk calculators and risk factors for Syphilis classification

Overview

Syphilis may be classified according to the development of disease into 2 groups: congenital and acquired. Acquired syphilis may be classified further into 5 subtypes: primary, secondary, latent and tertiary syphilis.

Classification

There is no established clasification system for syphilis. However, it may be classified into following subtypes:<ref name=abc>http://www.cdc.gov/std/stats10/app-casedef.htm Accessed on September 19, 2016>

Congenital

• Early

• Manifests before 2 years of age

• Late

• Manifests after 2 years of age

Acquired

• Mode of transmission is direct contact with infectious lesion
• It may spread by sexual intercouse, touching and kissing a person having active lesions

Primary

• Manifests as papule which breaks to form painless chancre
• Lasts for 3 to 6 weeks

Secondary

• Develops weeks to months after chancre
• Manifests with constitutional sypmtoms such as fever, headache, malaise, lymphadenopathy and localised or diffuse rash called condyloma lata
• Lasts 1-6 months

Latent syphilis

• Early latent

• Asymptomatic < 12 years

• Late latent

• Asymptomatic >12 years

Tertiary or gummatous syphilis

• Cardiovascular
• CNS

• Asymptomatic
• Meningiovascular
• Tabes dorsalis
• Parenchymatous

• Other