Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions
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==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
The [[symptoms]] of [[SIADH]] can occur at any age. If untreated can lead to[[ complications]] such as [[confusion]], [[seizures]], [[stupor]] and [[coma]]. | *The [[symptoms]] of [[SIADH]] can occur at any age. If left untreated can lead to [[complications]], such as [[confusion]], [[seizures]], [[stupor]], and [[coma]]. | ||
===Complications=== | ===Complications=== | ||
*Some of the [[complications]] of [[SIADH]] treatment are include [[cerebral edema]] and [[central pontine myelinolysis]], which are seen with rapid [[sodium]] correction. | |||
===Prognosis=== | ===Prognosis=== | ||
*The prognosis of [[SIADH|Syndrome of inappropriate antidiuretic hormone (SIADH)]] depends primarily on its cause. | *The prognosis of [[SIADH|Syndrome of inappropriate antidiuretic hormone (SIADH)]] depends primarily on its cause. | ||
**If the cause is [[drug| | **If the cause is [[drug|medications]], [[SIADH]] usually improves after discontinuing the medication. | ||
**[[SIADH]] secondary to an [[infection]], improves with the treatment of the infection. | **[[SIADH]] secondary to an [[infection]], improves with the treatment of the infection. | ||
**[[SIADH]] secondary to [[cancers]], has poor outcome. | **[[SIADH]] secondary to [[cancers]], has poor outcome. | ||
Revision as of 18:49, 11 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
The symptoms of SIADH can occur at any age. If left untreated can lead to complications, such as confusion, seizures, stupor, and coma.
Natural History, Complications, and Prognosis
- The symptoms of SIADH can occur at any age. If left untreated can lead to complications, such as confusion, seizures, stupor, and coma.
Complications
- Some of the complications of SIADH treatment are include cerebral edema and central pontine myelinolysis, which are seen with rapid sodium correction.
Prognosis
- The prognosis of Syndrome of inappropriate antidiuretic hormone (SIADH) depends primarily on its cause.
- If the cause is medications, SIADH usually improves after discontinuing the medication.
- SIADH secondary to an infection, improves with the treatment of the infection.
- SIADH secondary to cancers, has poor outcome.
- Patients with SIADH have different signs, symptoms and prognosis depending on the etiology of SIADH. Serum sodium concentration at short-term follow-up is predictive of long-term survival. Rapid correction of serum sodium concentration can lead to various complications. [1]
References
- ↑ Tzoulis P, Carr H, Bagkeris E, Bouloux PM (2017). "Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care". Endocrine. 55 (2): 539–546. doi:10.1007/s12020-016-1161-9. PMC 5272879. PMID 27837439.