Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions
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{{Syndrome of inappropriate antidiuretic hormone}} | {{Syndrome of inappropriate antidiuretic hormone}} | ||
{{CMG}}; {{AE}} {{Vbe}} | {{CMG}}; {{AE}}{{Vbe}} | ||
==Overview== | ==Overview== | ||
The [[symptoms]] of [[SIADH]] can occur at any age. If left untreated can lead to [[complications]], such as [[confusion]], [[seizures]], [[stupor]], and [[coma]]. | |||
==Natural History, Complications, and Prognosis== | |||
The [[symptoms]] of [[SIADH]] can occur at any age. If untreated can lead to[[ complications]] such as [[confusion]], [[seizures]], [[stupor]] and [[coma]]. | The [[symptoms]] of [[SIADH]] can occur at any age. If untreated can lead to[[ complications]] such as [[confusion]], [[seizures]], [[stupor]] and [[coma]]. | ||
== | ===Complications=== | ||
Some of the [[complications]] of [[SIADH]] treatment are, [[cerebral edema]] and [[central pontine myelinolysis]] which are seen with rapid [[sodium]] correction. | |||
Some of the [[complications]] | |||
The prognosis of [[Syndrome of inappropriate antidiuretic hormone | ===Prognosis=== | ||
*The prognosis of [[SIADH|Syndrome of inappropriate antidiuretic hormone (SIADH)]] depends primarily on its cause. | |||
**If the cause is [[drug|medication]]s, [[SIADH]] usually improves after discontinuing the medication. | |||
**[[SIADH]] secondary to an [[infection]], improves with the treatment of the infection. | |||
**[[SIADH]] secondary to [[cancers]], has poor outcome. | |||
**[[Patients]] with SIADH have different signs, symptoms and [[prognosis]] depending on the [[etiology]] of SIADH. Serum [[sodium]] concentration at short-term follow-up is predictive of long-term survival. Rapid correction of serum [[sodium]] concentration can lead to various complications. <ref name="pmid27837439">{{cite journal |vauthors=Tzoulis P, Carr H, Bagkeris E, Bouloux PM |title=Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care |journal=Endocrine |volume=55 |issue=2 |pages=539–546 |year=2017 |pmid=27837439 |pmc=5272879 |doi=10.1007/s12020-016-1161-9 |url=}}</ref> | |||
==References== | ==References== | ||
Revision as of 17:18, 11 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
The symptoms of SIADH can occur at any age. If left untreated can lead to complications, such as confusion, seizures, stupor, and coma.
Natural History, Complications, and Prognosis
The symptoms of SIADH can occur at any age. If untreated can lead tocomplications such as confusion, seizures, stupor and coma.
Complications
Some of the complications of SIADH treatment are, cerebral edema and central pontine myelinolysis which are seen with rapid sodium correction.
Prognosis
- The prognosis of Syndrome of inappropriate antidiuretic hormone (SIADH) depends primarily on its cause.
- If the cause is medications, SIADH usually improves after discontinuing the medication.
- SIADH secondary to an infection, improves with the treatment of the infection.
- SIADH secondary to cancers, has poor outcome.
- Patients with SIADH have different signs, symptoms and prognosis depending on the etiology of SIADH. Serum sodium concentration at short-term follow-up is predictive of long-term survival. Rapid correction of serum sodium concentration can lead to various complications. [1]
References
- ↑ Tzoulis P, Carr H, Bagkeris E, Bouloux PM (2017). "Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care". Endocrine. 55 (2): 539–546. doi:10.1007/s12020-016-1161-9. PMC 5272879. PMID 27837439.