Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions
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==Complications== | ==Complications== | ||
Common complications of SIADH are: | Common [[complications]] of [[SIADH]] are: | ||
*Hyponatremia | *[[Hyponatremia]] | ||
*Central pontine myelinolysis ( When sodium levels are corrected too rapidly) | *[[Central pontine myelinolysis]] ( When sodium levels are corrected too rapidly) | ||
*Cerebral edema | *[[Cerebral edema]] | ||
==Prognosis== | ==Prognosis== | ||
Revision as of 19:52, 14 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Patients with SIADH have different characteristics and a different prognosis according to etiology. Serum sodium concentration at short-term follow-up is predictive of long-term survival. These findings might havediagnostic and treatmentrelated implications.
Natural History
If left untreated 2.5%-30% of hospitalized patients with SIADH may progress to develop:
- Hyponatremia(Serum sodium concentration at short-term follow-up is predictive of long-term survival). T
- Cerebral edema
- Central pontine myelinolysis(if sodium levels are corrected too rapidly)
Complications
Common complications of SIADH are:
- Hyponatremia
- Central pontine myelinolysis ( When sodium levels are corrected too rapidly)
- Cerebral edema
Prognosis
The prognosis of SIADH is good with treatment. Without treatment,SIADH will result in complications like hyponatremia,confusion,seizures,stupor and coma. [1]
References
- ↑ Tzoulis P, Carr H, Bagkeris E, Bouloux PM (2017). "Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care". Endocrine. 55 (2): 539–546. doi:10.1007/s12020-016-1161-9. PMC 5272879. PMID 27837439.