Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions

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==Prognosis==
==Prognosis==
The prognosis of (disease name) is poor/good with treatment. Without treatment, (disease name) will result in ___. (Disease name) is associated with a 1/5/10 year mortality of __ among patient with ______ (for example high grade lesions). The presence of ___ is associated with a particularly poor prognosis among patients with (disease nam
The prognosis of SIADH is good with treatment. Without treatment,SIADH will result in complications like hyponatremia,confusion,seizures,stupor and coma. <ref name="pmid27837439">{{cite journal |vauthors=Tzoulis P, Carr H, Bagkeris E, Bouloux PM |title=Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care |journal=Endocrine |volume=55 |issue=2 |pages=539–546 |year=2017 |pmid=27837439 |pmc=5272879 |doi=10.1007/s12020-016-1161-9 |url=}}</ref>


==References==
==References==

Revision as of 17:46, 9 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]

Overview

Patients with SIADH have different characteristics and a different prognosis according to SIADH etiology. Serum sodium concentration at short-term follow-up is predictive of long-term survival. These findings might have diagnostic and treatment-related implications.

Natural History

If left untreated 2.5%-30% of hospitalized patients with SIADH may progress to develop

  • Hyponatremia(Serum sodium concentration at short-term follow-up is predictive of long-term survival). T
  • Cerebral edema
  • Central pontine myelinolysis(if sodium levels are corrected too rapidly)

Complications

Common complications of SIADH are:

  • Hyponatremia
  • Central pontine myelinolysis ( When sodium levels are corrected too rapidly)
  • Cerebral edema

Prognosis

The prognosis of SIADH is good with treatment. Without treatment,SIADH will result in complications like hyponatremia,confusion,seizures,stupor and coma. [1]

References

  1. Tzoulis P, Carr H, Bagkeris E, Bouloux PM (2017). "Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care". Endocrine. 55 (2): 539–546. doi:10.1007/s12020-016-1161-9. PMC 5272879. PMID 27837439.


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