Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
If left untreated 2.5%-30% of hospitalized patients with [[SIADH]] may progress to develop | |||
*Hyponatremia(Serum sodium concentration at short-term follow-up is predictive of long-term survival). T | |||
*Cerebral edema | |||
*Central pontine myelinolysis(if sodium levels are corrected too rapidly) | |||
==Complications== | ==Complications== |
Revision as of 16:47, 9 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Patients with SIADH have different characteristics and a different prognosis according to SIADH etiology. Serum sodium concentration at short-term follow-up is predictive of long-term survival. These findings might have diagnostic and treatment-related implications.
Natural History
If left untreated 2.5%-30% of hospitalized patients with SIADH may progress to develop
- Hyponatremia(Serum sodium concentration at short-term follow-up is predictive of long-term survival). T
- Cerebral edema
- Central pontine myelinolysis(if sodium levels are corrected too rapidly)
Complications
Some of the complications of SIADH are:
- Hyponatremia
- Central pontine myelinolysis ( When sodium levels are corrected too rapidly)
- Cerebral edema
Prognosis
The prognosis of Syndrome of inappropriate antidiuretic hormone (SIADH) depends largely on its cause. If the cause is drugs, SIADH usually improves after stopping a drug. If SIADH is associated with some infection, treating the infection may be important. For those SIADH with cancers, the outcomes may be poor. Patients with SIADH have different characteristics and a different prognosis according to SIADH etiology. Serum sodium concentration at short-term follow-up is predictive of long-term survival. These findings might have diagnostic and treatment-related implications. [1]
References
- ↑ Shepshelovich D, Leibovitch C, Klein A, Zoldan S, Milo G, Shochat T, Rozen-zvi B, Gafter-Gvili A, Lahav M (2015). "The syndrome of inappropriate antidiuretic hormone secretion: Distribution and characterization according to etiologies". Eur. J. Intern. Med. 26 (10): 819–24. doi:10.1016/j.ejim.2015.10.020. PMID 26563934.