Splenic infarction causes: Difference between revisions

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{{CMG}}
{{CMG}}
==Overview==
==Overview==
==Causes==
<small><ref name="pmid17562611">{{cite journal |author=Suzuki Y, Shichishima T, Mukae M, ''et al'' |title=Splenic infarction after Epstein-Barr virus infection in a patient with hereditary spherocytosis |journal=Int. J. Hematol. |volume=85 |issue=5 |pages=380–3 |year=2007 |month=June |pmid=17562611 |doi=10.1532/IJH97.07208 |url=}}</ref> <ref name="pmid15550267">{{cite journal |author=Bonnard P, Guiard-Schmid JB, Develoux M, Rozenbaum W, Pialoux G |title=Splenic infarction during acute malaria |journal=Trans. R. Soc. Trop. Med. Hyg. |volume=99 |issue=1 |pages=82–6 |year=2005 |month=January |pmid=15550267 |doi=10.1016/j.trstmh.2004.06.005 |url=}}</ref> <ref name="pmid18171204">{{cite journal |author=Florescu D, Sordillo PP, Glyptis A, ''et al'' |title=Splenic infarction in human babesiosis: two cases and discussion |journal=Clin. Infect. Dis. |volume=46 |issue=1 |pages=e8–11 |year=2008 |month=January |pmid=18171204 |doi=10.1086/524081 |url=}}</ref> <ref name="pmid18604554">{{cite journal |author=Breuer C, Janssen G, Laws HJ, ''et al'' |title=Splenic infarction in a patient hereditary spherocytosis, protein C deficiency and acute infectious mononucleosis |journal=Eur. J. Pediatr. |volume=167 |issue=12 |pages=1449–52 |year=2008 |month=December |pmid=18604554 |doi=10.1007/s00431-008-0781-3 |url=}}</ref> <ref name="pmid18684317">{{cite journal |author=Almeida JA, Riordan SM |title=Splenic infarction complicating percutaneous transluminal coeliac artery stenting for chronic mesenteric ischaemia: a case report |journal=J Med Case Reports |volume=2 |issue= |pages=261 |year=2008 |pmid=18684317 |pmc=2533016 |doi=10.1186/1752-1947-2-261 |url=}}</ref> <ref name="pmid10852290">{{cite journal |author=Rentsch J, McColl G |title=Splenic infarction in Wegener's granulomatosis |journal=J. Rheumatol. |volume=27 |issue=6 |pages=1554–5 |year=2000 |month=June |pmid=10852290 |doi= |url=}}</ref> <ref name="pmid16767537">{{cite journal |author=Arora A, Arora S |title=Spontaneous splenic infarction associated with sumatriptan use |journal=J Headache Pain |volume=7 |issue=4 |pages=214–6 |year=2006 |month=September |pmid=16767537 |doi=10.1007/s10194-006-0291-5 |url=}}</ref> <ref name="pmid17138227">{{cite journal |author=Malka D, Van den Eynde M, Boige V, Dromain C, Ducreux M |title=Splenic infarction and bevacizumab |journal=Lancet Oncol. |volume=7 |issue=12 |pages=1038 |year=2006 |month=December |pmid=17138227 |doi=10.1016/S1470-2045(06)70980-9 |url=}}</ref></small>
===Hematologic disorders - Malignant===
* [[Leukemia]]
* [[Lymphoma]] (i.e., [[Hodgkin lymphoma]], [[Non-Hodgkin lymphoma]])
* [[Myelofibrosis]]
===Hematologic disorders - Benign===
* [[Hypercoagulable states]]
:* [[Protein C deficiency]]
:* [[Protein S deficiency]]
:* [[Oral contraceptive]]s
:* [[Lupus anticoagulant]]
* [[Erythropoietin|Erythropoietin therapy]]
* [[venous thrombosis|Idiopathic venous thrombosis]]
* [[Polycythemia vera]]
* [[Sickle cell disease|Sickle hemoglobinopathies]]
===Embolic disorders===
* [[Endocarditis]]
* [[Atrial fibrillation]]
* [[Prosthetic mitral valve]]
* Paradoxical emboli from right heart
* Left ventricular mural thrombus following myocardial infarct
* Infected thoracic aortic graft
* HIV-associated mycobacterial infections
===Vascular disorders===
===Autoimmune/collagen vascular disease===
* [[SLE ]]
* [[Kawasaki disease ]]
* [[Wegener’s granulomatosis ]]
* [[Polyarteritis nodosa]]
===Trauma===
* Blunt trauma
* Torsion of the wandering spleen
* [[Seldinger technique|Left heart catheterization via femoral artery approach]]
* [[Sclerotherapy of bleeding gastric varices]]
* [[Pitressin]] infusion
* Embolization for splenic bleeding
===Operative etiologies===
* [[Pancreatectomy]]
* [[Liver transplantation]]
===Infections===
* [[Meningococcaemia]]
* [[Kala-azar]] ([[visceral leishmaniasis]])
* [[Infectious mononucleosis]]
* [[Clostridium perfringens]]
* [[Campylobacter fetus]]
* [[Salmonellosis]]
* [[Plasmodium vivax]]
* [[Plasmodium falciparum]]
* [[Leptospirosis]]
===Medications===
*[[Naratriptan]]
* [[Sumatriptan]]
===Miscellaneous etiologies===
* [[Splenic vein thrombosis]]
* [[Pancreatitis]]
* [[Amyloidosis]]
* [[Sarcoidosis]]
* [[Pancreatic cancer]]
* [[Adult respiratory distress syndrome]] ([[ARDS]])
* Postpartum [[toxic shock syndrome]]
===Therapeutic splenic infarction===
Splenic infarction can be induced for the treatment of such conditions as [[portal hypertension]] or [[Ruptured spleen|splenic injury]]<ref name="pmid15761342">{{cite journal |author=Haan JM, Bochicchio GV, Kramer N, Scalea TM |title=Nonoperative management of blunt splenic injury: a 5-year experience |journal=J Trauma |volume=58 |issue=3 |pages=492–8 |year=2005 |month=March |pmid=15761342 |doi= |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0022-5282&volume=58&issue=3&spage=492}}</ref>. It can also be used prior to [[splenectomy]] for the prevention of [[blood loss]].
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 16:14, 6 February 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Causes

[1] [2] [3] [4] [5] [6] [7] [8]

Hematologic disorders - Malignant

Hematologic disorders - Benign

Embolic disorders

  • Paradoxical emboli from right heart
  • Left ventricular mural thrombus following myocardial infarct
  • Infected thoracic aortic graft
  • HIV-associated mycobacterial infections

Vascular disorders

Autoimmune/collagen vascular disease

Trauma

  • Blunt trauma
  • Torsion of the wandering spleen
  • Embolization for splenic bleeding

Operative etiologies

Infections

Medications

Miscellaneous etiologies

Therapeutic splenic infarction

Splenic infarction can be induced for the treatment of such conditions as portal hypertension or splenic injury[9]. It can also be used prior to splenectomy for the prevention of blood loss.

References

  1. ↑ Suzuki Y, Shichishima T, Mukae M; et al. (2007). "Splenic infarction after Epstein-Barr virus infection in a patient with hereditary spherocytosis". Int. J. Hematol. 85 (5): 380–3. doi:10.1532/IJH97.07208. PMID 17562611. Unknown parameter |month= ignored (help)
  2. ↑ Bonnard P, Guiard-Schmid JB, Develoux M, Rozenbaum W, Pialoux G (2005). "Splenic infarction during acute malaria". Trans. R. Soc. Trop. Med. Hyg. 99 (1): 82–6. doi:10.1016/j.trstmh.2004.06.005. PMID 15550267. Unknown parameter |month= ignored (help)
  3. ↑ Florescu D, Sordillo PP, Glyptis A; et al. (2008). "Splenic infarction in human babesiosis: two cases and discussion". Clin. Infect. Dis. 46 (1): e8–11. doi:10.1086/524081. PMID 18171204. Unknown parameter |month= ignored (help)
  4. ↑ Breuer C, Janssen G, Laws HJ; et al. (2008). "Splenic infarction in a patient hereditary spherocytosis, protein C deficiency and acute infectious mononucleosis". Eur. J. Pediatr. 167 (12): 1449–52. doi:10.1007/s00431-008-0781-3. PMID 18604554. Unknown parameter |month= ignored (help)
  5. ↑ Almeida JA, Riordan SM (2008). "Splenic infarction complicating percutaneous transluminal coeliac artery stenting for chronic mesenteric ischaemia: a case report". J Med Case Reports. 2: 261. doi:10.1186/1752-1947-2-261. PMC 2533016. PMID 18684317.
  6. ↑ Rentsch J, McColl G (2000). "Splenic infarction in Wegener's granulomatosis". J. Rheumatol. 27 (6): 1554–5. PMID 10852290. Unknown parameter |month= ignored (help)
  7. ↑ Arora A, Arora S (2006). "Spontaneous splenic infarction associated with sumatriptan use". J Headache Pain. 7 (4): 214–6. doi:10.1007/s10194-006-0291-5. PMID 16767537. Unknown parameter |month= ignored (help)
  8. ↑ Malka D, Van den Eynde M, Boige V, Dromain C, Ducreux M (2006). "Splenic infarction and bevacizumab". Lancet Oncol. 7 (12): 1038. doi:10.1016/S1470-2045(06)70980-9. PMID 17138227. Unknown parameter |month= ignored (help)
  9. ↑ Haan JM, Bochicchio GV, Kramer N, Scalea TM (2005). "Nonoperative management of blunt splenic injury: a 5-year experience". J Trauma. 58 (3): 492–8. PMID 15761342. Unknown parameter |month= ignored (help)

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