Spectinomycin: Difference between revisions

Revision as of 01:14, 24 December 2013

{{Spectinomycin}} Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Spectinomycin (marketed as the hydrochloride salt spectinomycin hydrochloride under the trade name Trobicin) is an aminocyclitol antibiotic produced by the bacterium Streptomyces spectabilis.

US Brand Names

Trobicin^®

FDA Package Insert

Mechanisms of Action

It binds to the 30S ribosomal subunit in invading bacteria and interrupts protein synthesis.

References

@@ Line 1: / Line 1: @@
-{{drugbox
+__NOTOC__
-| IUPAC_name = (2''R'',4a''R'',5a''R'',6''S'',7''S'',8''R'',9''S'',9a''R'',10a''S'')-<br>4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)<br>decahydro-4''H''-pyrano[2,3-b][1,4]benzodioxin-4-one
+{{<font color="#550099">Spectinomycin</font>}}
-| image = Spectinomycin.svg
+{{CMG}}
-| CAS_number = 1695-77-8
-| ATC_prefix = J01
-| ATC_suffix = XX04
-| ATC_supplemental =
-| PubChem = 15541
-| DrugBank = APRD01232
-| C = 14 | H = 24 | N = 2 | O = 7
-| molecular_weight = 332.35 g/mol
-| bioavailability =
-| protein_bound =
-| metabolism =
-| elimination_half-life =
-| pregnancy_US = B
-| legal_status =
-| routes_of_administration =
-}}
-{{SI}}
+==Overview==
+Spectinomycin (marketed as the [[hydrochloride]] salt '''spectinomycin hydrochloride''' under the trade name '''Trobicin''') is an [[aminocyclitol]] [[antibiotic]] produced by the [[bacteria|bacterium]] ''[[Streptomyces spectabilis]]''.
-'''Spectinomycin''' (marketed as the [[hydrochloride]] salt '''spectinomycin hydrochloride''' under the trade name '''Trobicin''') is an [[aminocyclitol]] [[antibiotic]] produced by the [[bacteria|bacterium]] ''[[Streptomyces spectabilis]]''.
+==Category==
+Aminocyclitol
-==Mechanism==
+==US Brand Names==
-It binds to the [[30S]] [[ribosome|ribosomal]] subunit in invading bacteria and interrupts protein synthesis.
+Trobicin<sup>®</sup>
-==Uses==
+==FDA Package Insert==
-It is given by [[Injection (medicine)|injection]] to treat [[gonorrhea]], especially in patients who are allergic to [[penicillin]]s.
+'''[[Spectinomycin description|Description]]'''
+'''| [[Spectinomycin clinical pharmacology|Clinical Pharmacology]]'''
+'''| [[Spectinomycin microbiology|Microbiology]]'''
+'''| [[Spectinomycin indications and usage|Indications and Usage]]'''
+'''| [[Spectinomycin contraindications|Contraindications]]'''
+'''| [[Spectinomycin warnings and precautions|Warnings and Precautions]]'''
+'''| [[Spectinomycin adverse reactions|Adverse Reactions]]'''
+'''| [[Spectinomycin overdosage|Overdosage]]'''
+'''| [[Spectinomycin clinical studies|Clinical Studies]]'''
+'''| [[Spectinomycin dosage and administration|Dosage and Administration]]'''
+'''| [[Spectinomycin compatibility reconstitution and stability|Compatibility, Reconstitution, and Stability]]'''
+'''| [[Spectinomycin directions for use|Directions For Use]]'''
+'''| [[Spectinomycin how supplied|How Supplied]]'''
+'''| [[Spectinomycin labels and packages|Labels and Packages]]'''
-==Side effects==
+==Mechanisms of Action==
-Side effects include [[pruritus|itching]], [[chills]], stomach-ash, and [[erythema|red rash]].
+It binds to the [[30S]] [[ribosome|ribosomal]] subunit in invading bacteria and interrupts protein synthesis.
+==References==
+{{Reflist|2}}
-{{AminoglycosideAntiBiotics}}
-{{Other antibacterials}}
 [[Category:Antibiotics]]
+[[Category:Wikinfect]]
-[[de:Spectinomycin]]
-{{WH}}
-{{WikiDoc Sources}}