Sickle-cell disease differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
In some cases, it can be difficult to differentiate sickle cell disease from other diagnoses, given that there may be significant overlap of symptoms. | In some cases, it can be difficult to differentiate sickle cell disease from other diagnoses, given that there may be significant overlap of symptoms.<ref name="pmid25742458">{{cite journal| author=Sankaran VG, Weiss MJ| title=Anemia: progress in molecular mechanisms and therapies. | journal=Nat Med | year= 2015 | volume= 21 | issue= 3 | pages= 221-30 | pmid=25742458 | doi=10.1038/nm.3814 | pmc=4452951 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25742458 }} </ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
| Line 11: | Line 11: | ||
:*[[Thalassemia]] | :*[[Thalassemia]] | ||
:*Acute leukemia | :*Acute leukemia | ||
:*[[Autoimmune hemolytic anemia]] | :*[[Autoimmune hemolytic anemia]]<ref name="pmid25742458">{{cite journal| author=Sankaran VG, Weiss MJ| title=Anemia: progress in molecular mechanisms and therapies. | journal=Nat Med | year= 2015 | volume= 21 | issue= 3 | pages= 221-30 | pmid=25742458 | doi=10.1038/nm.3814 | pmc=4452951 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25742458 }} </ref> | ||
:*HbSC disease | :*HbSC disease | ||
:*HbS-beta-thalassemia | :*HbS-beta-thalassemia | ||
Revision as of 20:26, 14 October 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
In some cases, it can be difficult to differentiate sickle cell disease from other diagnoses, given that there may be significant overlap of symptoms.[1]
Differential Diagnosis
- The differential diagnosis of sickle cell disease includes other conditions that may present with fatigue, infection, bone pain, such as:
- Thalassemia
- Acute leukemia
- Autoimmune hemolytic anemia[1]
- HbSC disease
- HbS-beta-thalassemia
- Septic arthritis
- Polycythemia vera
- Systemic lupus erythematosus
- Other hemoglobinopathies
References
- ↑ 1.0 1.1 Sankaran VG, Weiss MJ (2015). "Anemia: progress in molecular mechanisms and therapies". Nat Med. 21 (3): 221–30. doi:10.1038/nm.3814. PMC 4452951. PMID 25742458.