Revision as of 14:55, 6 September 2012 by WikiBot (talk | contribs) (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Sialidase, accession number PF02973 is a widespread enzyme that catalyzes the hydrolysis of terminal acylneuraminic residues from oligosaccharides, glycolipids and glycoproteins. Also called neuraminidase.

It is present as a surface antigen in myxo viruses, hence sialidase inhibitors are used in anti-viral drugs.[1]

Deficiency of this enzyme, an autosomal recessive trait, causes sialidosis; enzyme activity is also lacking in galactosialidosis. The EC nomenclature is exo-α-sialidase.



  1. 1: Mol Gen Genet. 1991 Apr;226(1-2):190-7. The sialidase gene from Clostridium septicum: cloning, sequencing, expression in Escherichia coli and identification of conserved sequences in sialidases and other proteins Rothe B, Rothe B, Roggentin P, Schauer R.; Biochemisches Institut, Christian-Albrechts-Universitat zu Kiel, FRG.

External links

Template:WikiDoc Sources