Sacrococcygeal teratoma history and symptoms: Difference between revisions

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'''For patient information click [[Sacrococcygeal teratoma (patient information)|here]]'''
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{{Sacrococcygeal teratoma}}
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{{CMG}}{{AE}}{{Sab}}{{MGS}}


==Overview==
==Overview==
'''Sacrococcygeal teratoma''' (SCT) is a [[teratoma]] (a kind of tumor) located at the base of the [[coccyx]] (tailbone). It is thought to be a derivative of the [[primitive streak]].
The [[hallmark]] of sacrococcygeal teratoma is a protruding mass at the sacrococcygeal region. It is important to obtain the history about the onset, and the progression of the [[Symptom|symptoms]]. Most common [[Symptom|symptoms]] of sacrococcygeal teratoma are due to compression caused by the large [[tumor]] mass. Maternal [[Symptom|symptoms]] can include [[hypertension]], [[vomiting]], and [[Pedal edema|peripheral edema]]. [[Adult|Adults]] can present with [[Low back pain|lower back pain]], [[Paresthesia|tingling and numbness]] of the [[Lower limb|lower limbs]], weakness, and [[constipation]].


==History and symptoms==
==History and Symptoms==
 
[[Symptom|Symptoms]] of sacrococcygeal teratoma depend on the size of the [[tumor]]. <ref name="hns">Sacrococcygeal teratoma. RareDisease (2015)https://rarediseases.org/rare-diseases/sacrococcygeal-teratoma/ Accessed on December 15th, 2015</ref>
At [[birth]], the usual presentation is a visible lump or mass under the skin at the top of the buttocks crease. If not visible, it can sometimes be felt; gently prodded, it feels somewhat like a hardboiled egg. A small SCT, if it is entirely inside the body, may not present for years, until it grows large enough to cause pain, constipation and other symptoms of a large mass inside the [[pelvis]], or until it begins to extend out of the pelvisEven a relatively large SCT may be missed, if it is internal, because the bony [[pelvis]] conceals and protects it.  [[Mediastinal tumor]]s, including teratomas, are similarly concealed and protected by the [[rib cage]].
===Common Symptoms===
 
*Small sacrococcygeal teratomas are [[asymptomatic]].
Some SCTs are discovered when a child begins to talk at about age 2 years and complains of their bottom hurting or feeling "poopy" when they ride in a car seat.
*Mass over the [[Sacrum|sacro]]-[[Coccyx|coccygeal]] region.<ref>{{Cite journal
 
  | author = [[Bappa Mandal]], [[Gaurav Chatterjee]], [[Kajari Bhattacharya]], [[Dipankar Roy]], [[Ram Narayan Das]] & [[Uttara Chatterjee]]
Other tumors can occur in the sacrococcygeal and/or presacral regions<ref name="pmid6366733">{{cite journal
| title = Sacrococcygeal teratoma with complete adrenal gland
| author = Bale PM
| journal = [[Journal of cancer research and therapeutics]]
| title = Sacrococcygeal developmental abnormalities and tumors in children.
| volume = 11
| journal = Perspectives in pediatric pathology
| issue = 4
| volume = 8
| pages = 1040
| issue = 1
| year = 2015
| pages = 9-56
| month = October-December
| year = 1984
| doi = 10.4103/0973-1482.148690
| pmid = 6366733
| pmid = 26881658
| doi =
}}</ref>
| issn =  
*[[Dystocia]]<ref>https://rarediseases.org</ref>
}}</ref> and hence must be ruled out to obtain a [[differential diagnosis]].  These include [[ependymoma|extraspinal ependymoma]]<ref name="pmid10726703">{{cite journal
*Maternal [[Symptom|symptoms]] may include:
| author = Aktuğ T, Hakgüder G, Sarioğlu S, Akgür FM, Olguner M, Pabuçcuoğlu U
**[[Hypertension]]<ref>{{Cite journal
| title = Sacrococcygeal extraspinal ependymomas: the role of coccygectomy.
| author = [[A. W. Flake]], [[M. R. Harrison]], [[N. S. Adzick]], [[J. M. Laberge]] & [[S. L. Warsof]]
| journal = J. Pediatr. Surg.
| title = Fetal sacrococcygeal teratoma
| volume = 35
| journal = [[Journal of pediatric surgery]]
| issue = 3
| volume = 21
| pages = 515-8
| issue = 7
| year = 2000
| pages = 563–566
| pmid = 10726703
| year = 1986
| doi =  
| month = July
| issn =  
| pmid = 3525800
}}</ref>, [[neuroblastoma]] and [[rhabdomyosarcoma]].  Smaller SCTs with an external component, seen in prenatal ultrasounds or at birth, often are mistaken for [[spina bifida]].
}}</ref>
**[[Pedal edema|Peripheral edema]]
**[[Vomiting]]
===Less Common Symptoms===
*[[Pus|Purulent]] [[vaginal discharge]]<ref>{{Cite journal
| author = [[Hannah N. Ladenhauf]], [[M. Georgina Brandtner]], [[Christa Schimke]], [[Mircia A. Ardelean]] & [[Roman Metzger]]
| title = Sacrococcygeal Teratoma Presenting with Vaginal Discharge and Polyp in an Infant
| journal = [[Journal of pediatric and adolescent gynecology]]
| volume = 31
| issue = 3
| pages = 318–320
| year = 2018
| month = June
| doi = 10.1016/j.jpag.2017.12.004
| pmid = 29269272
}}</ref>
*Recurrent [[Vagina|vaginal]] mass
*[[Abdominal distension]]<ref>{{Cite journal
| author = [[Venkata Sasidhar Majjiga]], [[Nidhi Bhatt]], [[Ali Kavianian]] & [[Beau Batton]]
| title = A newborn with massive intra-abdominal haemorrhage
| journal = [[BMJ case reports]]
| volume = 2015
| year = 2015
| month = September
| doi = 10.1136/bcr-2015-211279
  | pmid = 26336185
}}</ref>
===Symptoms in Adults===
*[[Low back pain|Lower back pain]]<ref>https://rarediseases.org</ref>
*Weakness
*[[Constipation]]
*Increased frequency of [[urine]] and [[Human feces|stool]]
*[[Paresthesia|Tingling and numbness]] in the [[Lower limb|lower limbs]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{Congenital malformations and deformations of nervous system|state=collapsed}}
{{Tumors|state=collapsed}}
{{Epithelial neoplasms}}
{{Pathology|state=collapsed}}
{{Joints of torso|state=collapsed}}


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[[es:Teratoma sacrococcígeo]]
[[fr:Tératome sacro-coccygien]]
[[it:Teratoma sacro-coccigeo]]
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Latest revision as of 19:31, 6 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2] Mirdula Sharma, MBBS [3]

Overview

The hallmark of sacrococcygeal teratoma is a protruding mass at the sacrococcygeal region. It is important to obtain the history about the onset, and the progression of the symptoms. Most common symptoms of sacrococcygeal teratoma are due to compression caused by the large tumor mass. Maternal symptoms can include hypertension, vomiting, and peripheral edema. Adults can present with lower back pain, tingling and numbness of the lower limbs, weakness, and constipation.

History and Symptoms

Symptoms of sacrococcygeal teratoma depend on the size of the tumor. [1]

Common Symptoms

Less Common Symptoms

Symptoms in Adults

References

  1. Sacrococcygeal teratoma. RareDisease (2015)https://rarediseases.org/rare-diseases/sacrococcygeal-teratoma/ Accessed on December 15th, 2015
  2. Bappa Mandal, Gaurav Chatterjee, Kajari Bhattacharya, Dipankar Roy, Ram Narayan Das & Uttara Chatterjee (2015). "Sacrococcygeal teratoma with complete adrenal gland". Journal of cancer research and therapeutics. 11 (4): 1040. doi:10.4103/0973-1482.148690. PMID 26881658. Unknown parameter |month= ignored (help)
  3. https://rarediseases.org
  4. A. W. Flake, M. R. Harrison, N. S. Adzick, J. M. Laberge & S. L. Warsof (1986). "Fetal sacrococcygeal teratoma". Journal of pediatric surgery. 21 (7): 563–566. PMID 3525800. Unknown parameter |month= ignored (help)
  5. Hannah N. Ladenhauf, M. Georgina Brandtner, Christa Schimke, Mircia A. Ardelean & Roman Metzger (2018). "Sacrococcygeal Teratoma Presenting with Vaginal Discharge and Polyp in an Infant". Journal of pediatric and adolescent gynecology. 31 (3): 318–320. doi:10.1016/j.jpag.2017.12.004. PMID 29269272. Unknown parameter |month= ignored (help)
  6. Venkata Sasidhar Majjiga, Nidhi Bhatt, Ali Kavianian & Beau Batton (2015). "A newborn with massive intra-abdominal haemorrhage". BMJ case reports. 2015. doi:10.1136/bcr-2015-211279. PMID 26336185. Unknown parameter |month= ignored (help)
  7. https://rarediseases.org

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