SNAP29: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Synaptosomal-associated protein 29''' is a [[protein]] that in humans is encoded by the ''SNAP29'' [[gene]].<ref name="pmid9852078">{{cite journal | vauthors = Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH | title = Three novel proteins of the syntaxin/SNAP-25 family | journal = J Biol Chem | volume = 273 | issue = 51 | pages = 34171–9 | date = January 1999 | pmid = 9852078 | pmc =  | doi = 10.1074/jbc.273.51.34171 }}</ref><ref name="pmid10591208">{{cite journal | vauthors = Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP | title = The DNA sequence of human chromosome 22 | journal = Nature | volume = 402 | issue = 6761 | pages = 489–95 | date = Dec 1999 | pmid = 10591208 | pmc = | doi = 10.1038/990031 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAP29 synaptosomal-associated protein, 29kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9342| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Synaptosomal-associated protein, 29kDa
| HGNCid = 11133
| Symbol = SNAP29
| AltSymbols =; CEDNIK; FLJ21051; SNAP-29
| OMIM = 604202
| ECnumber = 
| Homologene = 3512
| MGIid = 1914724
| GeneAtlas_image1 = PBB_GE_SNAP29_218327_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005484 |text = SNAP receptor activity}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0019717 |text = synaptosome}} {{GNF_GO|id=GO:0045202 |text = synapse}}
| Process = {{GNF_GO|id=GO:0006887 |text = exocytosis}} {{GNF_GO|id=GO:0006903 |text = vesicle targeting}} {{GNF_GO|id=GO:0006944 |text = membrane fusion}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9342
    | Hs_Ensembl = ENSG00000099940
    | Hs_RefseqProtein = NP_004773
    | Hs_RefseqmRNA = NM_004782
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 19543292
    | Hs_GenLoc_end = 19574109
    | Hs_Uniprot = O95721
    | Mm_EntrezGene = 67474
    | Mm_Ensembl = ENSMUSG00000022765
    | Mm_RefseqmRNA = NM_023348
    | Mm_RefseqProtein = NP_075837
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 17319595
    | Mm_GenLoc_end = 17344389
    | Mm_Uniprot = Q9ERB0
  }}
}}
'''Synaptosomal-associated protein, 29kDa''', also known as '''SNAP29''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNAP29 synaptosomal-associated protein, 29kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9342| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: SNAP29 synaptosomal-associated protein, 29kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9342| accessdate = }}</ref>
}}


==References==
==Model organisms==
{{reflist|2}}
{| class="wikitable sortable collapsible collapsed" border="1" cellpadding="2" style="float: right;" |
==Further reading==
|+ ''Snap29'' knockout mouse phenotype
{{refbegin | 2}}
|-
{{PBB_Further_reading
! Characteristic!! Phenotype
| citations =
*{{cite journal  | author=Steegmaier M, Yang B, Yoo JS, ''et al.'' |title=Three novel proteins of the syntaxin/SNAP-25 family. |journal=J. Biol. Chem. |volume=273 |issue= 51 |pages= 34171-9 |year= 1999 |pmid= 9852078 |doi=  }}
*{{cite journal  | author=Wong SH, Xu Y, Zhang T, ''et al.'' |title=GS32, a novel Golgi SNARE of 32 kDa, interacts preferentially with syntaxin 6. |journal=Mol. Biol. Cell |volume=10 |issue= 1 |pages= 119-34 |year= 1999 |pmid= 9880331 |doi=  }}
*{{cite journal  | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
*{{cite journal  | author=Scales SJ, Chen YA, Yoo BY, ''et al.'' |title=SNAREs contribute to the specificity of membrane fusion. |journal=Neuron |volume=26 |issue= 2 |pages= 457-64 |year= 2000 |pmid= 10839363 |doi=  }}
*{{cite journal  | author=Rotem-Yehudar R, Galperin E, Horowitz M |title=Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29. |journal=J. Biol. Chem. |volume=276 |issue= 35 |pages= 33054-60 |year= 2001 |pmid= 11423532 |doi= 10.1074/jbc.M009913200 }}
*{{cite journal  | author=Hohenstein AC, Roche PA |title=SNAP-29 is a promiscuous syntaxin-binding SNARE. |journal=Biochem. Biophys. Res. Commun. |volume=285 |issue= 2 |pages= 167-71 |year= 2001 |pmid= 11444821 |doi= 10.1006/bbrc.2001.5141 }}
*{{cite journal  | author=Su Q, Mochida S, Tian JH, ''et al.'' |title=SNAP-29: a general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 24 |pages= 14038-43 |year= 2002 |pmid= 11707603 |doi= 10.1073/pnas.251532398 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Martinez-Arca S, Rudge R, Vacca M, ''et al.'' |title=A dual mechanism controlling the localization and function of exocytic v-SNAREs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 15 |pages= 9011-6 |year= 2003 |pmid= 12853575 |doi= 10.1073/pnas.1431910100 }}
*{{cite journal  | author=Xu Y, Shi H, Wei S, ''et al.'' |title=Mutually exclusive interactions of EHD1 with GS32 and syndapin II. |journal=Mol. Membr. Biol. |volume=21 |issue= 4 |pages= 269-77 |year= 2005 |pmid= 15371016 |doi= 10.1080/09687680410001716871 }}
*{{cite journal  | author=Collins JE, Wright CL, Edwards CA, ''et al.'' |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Pan PY, Cai Q, Lin L, ''et al.'' |title=SNAP-29-mediated modulation of synaptic transmission in cultured hippocampal neurons. |journal=J. Biol. Chem. |volume=280 |issue= 27 |pages= 25769-79 |year= 2005 |pmid= 15890653 |doi= 10.1074/jbc.M502356200 }}
*{{cite journal  | author=Sprecher E, Ishida-Yamamoto A, Mizrahi-Koren M, ''et al.'' |title=A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma. |journal=Am. J. Hum. Genet. |volume=77 |issue= 2 |pages= 242-51 |year= 2005 |pmid= 15968592 |doi= 10.1086/432556 }}
*{{cite journal  | author=Carroll JS, Liu XS, Brodsky AS, ''et al.'' |title=Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. |journal=Cell |volume=122 |issue= 1 |pages= 33-43 |year= 2005 |pmid= 16009131 |doi= 10.1016/j.cell.2005.05.008 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
{{refend}}


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| ''[[Salmonella]]'' infection || bgcolor="#488ED3"|Normal<ref name="''Salmonella'' infection">{{cite web |url=http://www.sanger.ac.uk/mouseportal/phenotyping/MALE/salmonella-challenge/ |title=''Salmonella'' infection data for Snap29 |publisher=Wellcome Trust Sanger Institute}}</ref>
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| ''[[Citrobacter]]'' infection || bgcolor="#488ED3"|Normal<ref name="''Citrobacter'' infection">{{cite web |url=http://www.sanger.ac.uk/mouseportal/phenotyping/MALE/citrobacter-challenge/ |title=''Citrobacter'' infection data for Snap29 |publisher=Wellcome Trust Sanger Institute}}</ref>
|-
| colspan=2; style="text-align: center;" | All tests and analysis from<ref name="mgp_reference">{{cite journal | doi = 10.1111/j.1755-3768.2010.4142.x | title = The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice | year = 2010 | author = Gerdin AK | journal = Acta Ophthalmologica | volume = 88 | pages =  925–7 }}</ref><ref>[http://www.sanger.ac.uk/mouseportal/ Mouse Resources Portal], Wellcome Trust Sanger Institute.</ref>
|}
[[Model organism]]s have been used in the study of SNAP29 function. A conditional [[knockout mouse]] line, called ''Snap29<sup>tm1a(EUCOMM)Wtsi</sup>''<ref name="allele_ref">{{cite web |url=http://www.knockoutmouse.org/martsearch/search?query=Snap29 |title=International Knockout Mouse Consortium}}</ref><ref name="mgi_allele_ref">{{cite web |url=http://www.informatics.jax.org/searchtool/Search.do?query=MGI:4433565 |title=Mouse Genome Informatics}}</ref> was generated as part of the [[International Knockout Mouse Consortium]] program—a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.<ref name="pmid21677750">{{cite journal | vauthors = Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A | title = A conditional knockout resource for the genome-wide study of mouse gene function | journal = Nature | volume = 474 | issue = 7351 | pages = 337–342 | year = 2011 | pmid = 21677750 | pmc = 3572410 | doi = 10.1038/nature10163 }}</ref><ref name="mouse_library">{{cite journal | vauthors = Dolgin E | title = Mouse library set to be knockout | journal = Nature | volume = 474 | issue = 7351 | pages = 262–3 | year = 2011 | pmid = 21677718 | doi = 10.1038/474262a }}</ref><ref name="mouse_for_all_reasons">{{cite journal | vauthors = Collins FS, Rossant J, Wurst W | title = A Mouse for All Reasons | journal = Cell | volume = 128 | issue = 1 | pages = 9–13 | year = 2007 | pmid = 17218247 | doi = 10.1016/j.cell.2006.12.018 }}</ref>
 
Male and female animals underwent a standardized [[phenotypic screen]] to determine the effects of deletion.<ref name="mgp_reference" /><ref name="pmid21722353">{{cite journal | vauthors = van der Weyden L, White JK, Adams DJ, Logan DW | title = The mouse genetics toolkit: revealing function and mechanism. | journal = Genome Biol | volume = 12 | issue = 6 | pages = 224 | year = 2011 | pmid = 21722353 | pmc = 3218837 | doi = 10.1186/gb-2011-12-6-224 }}</ref> Twenty five tests were carried out on [[mutant]] mice and two significant abnormalities were observed.<ref name="mgp_reference" /> No [[homozygous]] mutant embryos were identified during gestation, and therefore none survived until [[weaning]]. The remaining tests were carried out on [[heterozygous]] mutant adult mice; no significant abnormalities were observed in these animals.<ref name="mgp_reference" />
 
== Interactions ==
 
SNAP29 has been shown to [[Protein-protein interaction|interact]] with [[Syntaxin 3]]<ref name=pmid9852078 /> and [[EHD1]].<ref name=pmid11423532>{{cite journal | vauthors = Rotem-Yehudar R, Galperin E, Horowitz M | title = Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29 | language =  | journal = J. Biol. Chem. | volume = 276 | issue = 35 | pages = 33054–60 | date = August 2001 | pmid = 11423532 | doi = 10.1074/jbc.M009913200 }}</ref>
{{Clear}}
 
== References ==
{{Reflist|35em}}
 
== Further reading ==
{{Refbegin|35em}}
* {{cite journal | vauthors = Wong SH, Xu Y, Zhang T, Griffiths G, Lowe SL, Subramaniam VN, Seow KT, Hong W | title = GS32, a novel Golgi SNARE of 32 kDa, interacts preferentially with syntaxin 6 | journal = Mol. Biol. Cell | volume = 10 | issue = 1 | pages = 119–34 | year = 1999 | pmid = 9880331 | pmc = 25158 | doi = 10.1091/mbc.10.1.119 }}
* {{cite journal | vauthors = Scales SJ, Chen YA, Yoo BY, Patel SM, Doung YC, Scheller RH | title = SNAREs contribute to the specificity of membrane fusion | journal = Neuron | volume = 26 | issue = 2 | pages = 457–64 | year = 2000 | pmid = 10839363 | doi = 10.1016/S0896-6273(00)81177-0 }}
* {{cite journal | vauthors = Rotem-Yehudar R, Galperin E, Horowitz M | title = Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29 | journal = J. Biol. Chem. | volume = 276 | issue = 35 | pages = 33054–60 | year = 2001 | pmid = 11423532 | doi = 10.1074/jbc.M009913200 }}
* {{cite journal | vauthors = Hohenstein AC, Roche PA | title = SNAP-29 is a promiscuous syntaxin-binding SNARE | journal = Biochem. Biophys. Res. Commun. | volume = 285 | issue = 2 | pages = 167–71 | year = 2001 | pmid = 11444821 | doi = 10.1006/bbrc.2001.5141 }}
* {{cite journal | vauthors = Su Q, Mochida S, Tian JH, Mehta R, Sheng ZH | title = SNAP-29: a general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 98 | issue = 24 | pages = 14038–43 | year = 2002 | pmid = 11707603 | pmc = 61163 | doi = 10.1073/pnas.251532398 }}
* {{cite journal | vauthors = Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V, Daviet L, Formstecher E, Hamburger A, Filippini F, D'Esposito M, Galli T | title = A dual mechanism controlling the localization and function of exocytic v-SNAREs | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 100 | issue = 15 | pages = 9011–6 | year = 2003 | pmid = 12853575 | pmc = 166429 | doi = 10.1073/pnas.1431910100 }}
* {{cite journal | vauthors = Xu Y, Shi H, Wei S, Wong SH, Hong W | title = Mutually exclusive interactions of EHD1 with GS32 and syndapin II | journal = Mol. Membr. Biol. | volume = 21 | issue = 4 | pages = 269–77 | year = 2005 | pmid = 15371016 | doi = 10.1080/09687680410001716871 }}
* {{cite journal | vauthors = Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I | title = A genome annotation-driven approach to cloning the human ORFeome | journal = Genome Biol. | volume = 5 | issue = 10 | pages = R84 | year = 2005 | pmid = 15461802 | pmc = 545604 | doi = 10.1186/gb-2004-5-10-r84 }}
* {{cite journal | vauthors = Pan PY, Cai Q, Lin L, Lu PH, Duan S, Sheng ZH | title = SNAP-29-mediated modulation of synaptic transmission in cultured hippocampal neurons | journal = J. Biol. Chem. | volume = 280 | issue = 27 | pages = 25769–79 | year = 2005 | pmid = 15890653 | pmc = 1864940 | doi = 10.1074/jbc.M502356200 }}
* {{cite journal | vauthors = Sprecher E, Ishida-Yamamoto A, Mizrahi-Koren M, Rapaport D, Goldsher D, Indelman M, Topaz O, Chefetz I, Keren H, O'brien TJ, Bercovich D, Shalev S, Geiger D, Bergman R, Horowitz M, Mandel H | title = A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma | journal = Am. J. Hum. Genet. | volume = 77 | issue = 2 | pages = 242–51 | year = 2005 | pmid = 15968592 | pmc = 1224527 | doi = 10.1086/432556 }}
* {{cite journal | vauthors = Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M | title = Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1 | journal = Cell | volume = 122 | issue = 1 | pages = 33–43 | year = 2005 | pmid = 16009131 | doi = 10.1016/j.cell.2005.05.008 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
{{Refend}}
 
{{Vesicular transport proteins}}
 
[[Category:Genes mutated in mice]]

Latest revision as of 06:44, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Synaptosomal-associated protein 29 is a protein that in humans is encoded by the SNAP29 gene.[1][2][3]

Function

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.[3]

Model organisms

Model organisms have been used in the study of SNAP29 function. A conditional knockout mouse line, called Snap29tm1a(EUCOMM)Wtsi[8][9] was generated as part of the International Knockout Mouse Consortium program—a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.[10][11][12]

Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.[6][13] Twenty five tests were carried out on mutant mice and two significant abnormalities were observed.[6] No homozygous mutant embryos were identified during gestation, and therefore none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice; no significant abnormalities were observed in these animals.[6]

Interactions

SNAP29 has been shown to interact with Syntaxin 3[1] and EHD1.[14]

References

  1. ↑ 1.0 1.1 Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH (January 1999). "Three novel proteins of the syntaxin/SNAP-25 family". J Biol Chem. 273 (51): 34171–9. doi:10.1074/jbc.273.51.34171. PMID 9852078.
  2. ↑ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
  3. ↑ 3.0 3.1 "Entrez Gene: SNAP29 synaptosomal-associated protein, 29kDa".
  4. ↑ "Salmonella infection data for Snap29". Wellcome Trust Sanger Institute.
  5. ↑ "Citrobacter infection data for Snap29". Wellcome Trust Sanger Institute.
  6. ↑ 6.0 6.1 6.2 6.3 Gerdin AK (2010). "The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice". Acta Ophthalmologica. 88: 925–7. doi:10.1111/j.1755-3768.2010.4142.x.
  7. ↑ Mouse Resources Portal, Wellcome Trust Sanger Institute.
  8. ↑ "International Knockout Mouse Consortium".
  9. ↑ "Mouse Genome Informatics".
  10. ↑ Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–342. doi:10.1038/nature10163. PMC 3572410. PMID 21677750.
  11. ↑ Dolgin E (2011). "Mouse library set to be knockout". Nature. 474 (7351): 262–3. doi:10.1038/474262a. PMID 21677718.
  12. ↑ Collins FS, Rossant J, Wurst W (2007). "A Mouse for All Reasons". Cell. 128 (1): 9–13. doi:10.1016/j.cell.2006.12.018. PMID 17218247.
  13. ↑ van der Weyden L, White JK, Adams DJ, Logan DW (2011). "The mouse genetics toolkit: revealing function and mechanism". Genome Biol. 12 (6): 224. doi:10.1186/gb-2011-12-6-224. PMC 3218837. PMID 21722353.
  14. ↑ Rotem-Yehudar R, Galperin E, Horowitz M (August 2001). "Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29". J. Biol. Chem. 276 (35): 33054–60. doi:10.1074/jbc.M009913200. PMID 11423532.

Further reading

Retrieved from "https://www.wikidoc.org/index.php?title=SNAP29&oldid=1420193"