Retinoic acid receptor beta: Difference between revisions

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__NOTOC__
{{Infobox gene}}
{{CMG}}
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
'''Retinoic acid receptor beta''' ('''RAR-beta'''), also known as '''NR1B2''' (nuclear receptor subfamily 1, group B, member 2) is a [[nuclear receptor]] that in humans is encoded by the ''RARB'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RARB retinoic acid receptor, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5915| accessdate = }}</ref><ref name="pmid2844650">{{cite journal | vauthors = Mattei MG, de Thé H, Mattei JF, Marchio A, Tiollais P, Dejean A | title = Assignment of the human hap retinoic acid receptor RAR beta gene to the p24 band of chromosome 3 | journal = Human Genetics | volume = 80 | issue = 2 | pages = 189–90 | date = Oct 1988 | pmid = 2844650 | doi = 10.1007/BF00702867 }}</ref>
{{GNF_Protein_box
| image = PBB_Protein_RARB_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1dsz.
| PDB = {{PDB2|1dsz}}, {{PDB2|1hra}}, {{PDB2|1xap}}, {{PDB2|1xdk}}
| Name = Retinoic acid receptor, beta
| HGNCid = 9865
| Symbol = RARB
| AltSymbols =; HAP; NR1B2; RRB2
| OMIM = 180220
| ECnumber = 
| Homologene = 68100
| MGIid = 97857
| GeneAtlas_image1 = PBB_GE_RARB_205080_at_tn.png
| GeneAtlas_image2 = PBB_GE_RARB_208530_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_RARB_208412_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003707 |text = steroid hormone receptor activity}} {{GNF_GO|id=GO:0003708 |text = retinoic acid receptor activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007165 |text = signal transduction}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5915
    | Hs_Ensembl = ENSG00000077092
    | Hs_RefseqProtein = NP_000956
    | Hs_RefseqmRNA = NM_000965
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 25190893
    | Hs_GenLoc_end = 25614424
    | Hs_Uniprot = P10826
    | Mm_EntrezGene = 218772
    | Mm_Ensembl = ENSMUSG00000017491
    | Mm_RefseqmRNA = NM_011243
    | Mm_RefseqProtein = NP_035373
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 15224106
    | Mm_GenLoc_end = 15612134
    | Mm_Uniprot = Q8K1P6
  }}
}}


==Overview==
== Function ==
'''Retinoic acid receptor beta''' ('''RAR-beta'''), also known as '''NR1B2''' (nuclear receptor subfamily 1, group B, member 2) is a [[nuclear receptor]] encoded by the {{gene|RARB}} gene.<ref name="entrez">{{cite web | title = Entrez Gene: RARB retinoic acid receptor, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5915| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of [[vitamin A]] which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a [[hepatitis B]] virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of [[vitamin A]] which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.<ref name="entrez">{{cite web | title = Entrez Gene: RARB retinoic acid receptor, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5915| accessdate = }}</ref>
}}


==See also==
== Interactions ==
 
Retinoic acid receptor beta has been shown to [[Protein-protein_interaction|interact]] with [[Nuclear receptor related 1 protein|NR4A2]].<ref name="pmid7705655">{{cite journal | vauthors = Perlmann T, Jansson L | title = A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1 | journal = Genes & Development | volume = 9 | issue = 7 | pages = 769–82 | date = Apr 1995 | pmid = 7705655 | doi = 10.1101/gad.9.7.769 }}</ref>
 
== See also ==
* [[Retinoic acid receptor]]
* [[Retinoic acid receptor]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Dejean A, de Thé H | title = Hepatitis B virus as an insertional mutagene in a human hepatocellular carcinoma | journal = Molecular Biology & Medicine | volume = 7 | issue = 3 | pages = 213–22 | date = Jun 1990 | pmid = 2170809 | doi =  }}
| citations =
* {{cite journal | vauthors = Sun SY | title = Retinoic acid receptor beta and colon cancer | journal = Cancer Biology & Therapy | volume = 3 | issue = 1 | pages = 87–8 | date = Jan 2004 | pmid = 14726690 | doi = 10.4161/cbt.3.1.686 }}
*{{cite journal | author=Dejean A, de Thé H |title=Hepatitis B virus as an insertional mutagene in a human hepatocellular carcinoma. |journal=Mol. Biol. Med. |volume=7 |issue= 3 |pages= 213-22 |year= 1990 |pmid= 2170809 |doi=  }}
* {{cite journal | vauthors = Saba N, Jain S, Khuri F | title = Chemoprevention in lung cancer | journal = Current Problems in Cancer | volume = 28 | issue = 5 | pages = 287–306 | year = 2004 | pmid = 15375805 | doi = 10.1016/j.currproblcancer.2004.05.005 }}
*{{cite journal | author=Sun SY |title=Retinoic acid receptor beta and colon cancer. |journal=Cancer Biol. Ther. |volume=3 |issue= 1 |pages= 87-8 |year= 2004 |pmid= 14726690 |doi= }}
* {{cite journal | vauthors = Klein O, Grignon Y, Civit T, Auque J, Marchal JC | title = [Methylation status of RARbeta gene promoter in low and high grade cerebral glioma. Comparison with normal tissue. Immuno-histochemical study of nuclear RARbeta expression in low and high grade cerebral glioma cells. Comparison with normal cells. 48 tumors] | journal = Neuro-Chirurgie | volume = 51 | issue = 3-4 Pt 1 | pages = 147–54 | date = Sep 2005 | pmid = 16389900 | doi =  }}
*{{cite journal | author=Saba N, Jain S, Khuri F |title=Chemoprevention in lung cancer. |journal=Current problems in cancer |volume=28 |issue= 5 |pages= 287-306 |year= 2004 |pmid= 15375805 |doi= }}
* {{cite journal | vauthors = Katahira M, Knegtel RM, Boelens R, Eib D, Schilthuis JG, van der Saag PT, Kaptein R | title = Homo- and heteronuclear NMR studies of the human retinoic acid receptor beta DNA-binding domain: sequential assignments and identification of secondary structure elements | journal = Biochemistry | volume = 31 | issue = 28 | pages = 6474–80 | date = Jul 1992 | pmid = 1321662 | doi = 10.1021/bi00143a017 }}
*{{cite journal | author=Klein O, Grignon Y, Civit T, ''et al.'' |title=[Methylation status of RARbeta gene promoter in low and high grade cerebral glioma. Comparison with normal tissue. Immuno-histochemical study of nuclear RARbeta expression in low and high grade cerebral glioma cells. Comparison with normal cells. 48 tumors] |journal=Neuro-Chirurgie |volume=51 |issue= 3-4 Pt 1 |pages= 147-54 |year= 2006 |pmid= 16389900 |doi=  }}
* {{cite journal | vauthors = Berrodin TJ, Marks MS, Ozato K, Linney E, Lazar MA | title = Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein | journal = Molecular Endocrinology | volume = 6 | issue = 9 | pages = 1468–78 | date = Sep 1992 | pmid = 1331778 | doi = 10.1210/me.6.9.1468 }}
*{{cite journal | author=Katahira M, Knegtel RM, Boelens R, ''et al.'' |title=Homo- and heteronuclear NMR studies of the human retinoic acid receptor beta DNA-binding domain: sequential assignments and identification of secondary structure elements. |journal=Biochemistry |volume=31 |issue= 28 |pages= 6474-80 |year= 1992 |pmid= 1321662 |doi= }}
* {{cite journal | vauthors = van der Leede BJ, Folkers GE, Kruyt FA, van der Saag PT | title = Genomic organization of the human retinoic acid receptor beta 2 | journal = Biochemical and Biophysical Research Communications | volume = 188 | issue = 2 | pages = 695–702 | date = Oct 1992 | pmid = 1332705 | doi = 10.1016/0006-291X(92)91112-4 }}
*{{cite journal | author=Berrodin TJ, Marks MS, Ozato K, ''et al.'' |title=Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. |journal=Mol. Endocrinol. |volume=6 |issue= 9 |pages= 1468-78 |year= 1992 |pmid= 1331778 |doi= }}
* {{cite journal | vauthors = Prentice A, Matthews CJ, Thomas EJ, Redfern CP | title = The expression of retinoic acid receptors in cultured human endometrial stromal cells and effects of retinoic acid | journal = Human Reproduction | volume = 7 | issue = 5 | pages = 692–700 | date = May 1992 | pmid = 1379266 | doi = 10.1093/oxfordjournals.humrep.a137721 }}
*{{cite journal | author=van der Leede BJ, Folkers GE, Kruyt FA, van der Saag PT |title=Genomic organization of the human retinoic acid receptor beta 2. |journal=Biochem. Biophys. Res. Commun. |volume=188 |issue= 2 |pages= 695-702 |year= 1992 |pmid= 1332705 |doi= }}
* {{cite journal | vauthors = Shen S, Kruyt FA, den Hertog J, van der Saag PT, Kruijer W | title = Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsiveness | journal = DNA Sequence | volume = 2 | issue = 2 | pages = 111–9 | year = 1992 | pmid = 1663808 | doi = 10.3109/10425179109039679 }}
*{{cite journal | author=Prentice A, Matthews CJ, Thomas EJ, Redfern CP |title=The expression of retinoic acid receptors in cultured human endometrial stromal cells and effects of retinoic acid. |journal=Hum. Reprod. |volume=7 |issue= 5 |pages= 692-700 |year= 1992 |pmid= 1379266 |doi= }}
* {{cite journal | vauthors = de Thé H, Vivanco-Ruiz MM, Tiollais P, Stunnenberg H, Dejean A | title = Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene | journal = Nature | volume = 343 | issue = 6254 | pages = 177–80 | date = Jan 1990 | pmid = 2153268 | doi = 10.1038/343177a0 }}
*{{cite journal | author=Shen S, Kruyt FA, den Hertog J, ''et al.'' |title=Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsiveness. |journal=DNA Seq. |volume=2 |issue= 2 |pages= 111-9 |year= 1992 |pmid= 1663808 |doi= }}
* {{cite journal | vauthors = Hoffmann B, Lehmann JM, Zhang XK, Hermann T, Husmann M, Graupner G, Pfahl M | title = A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter | journal = Molecular Endocrinology | volume = 4 | issue = 11 | pages = 1727–36 | date = Nov 1990 | pmid = 2177841 | doi = 10.1210/mend-4-11-1727 }}
*{{cite journal | author=de Thé H, Vivanco-Ruiz MM, Tiollais P, ''et al.'' |title=Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene. |journal=Nature |volume=343 |issue= 6254 |pages= 177-80 |year= 1990 |pmid= 2153268 |doi= 10.1038/343177a0 }}
* {{cite journal | vauthors = de Thé H, Marchio A, Tiollais P, Dejean A | title = A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma | journal = Nature | volume = 330 | issue = 6149 | pages = 667–70 | year = 1988 | pmid = 2825037 | doi = 10.1038/330667a0 }}
*{{cite journal | author=Hoffmann B, Lehmann JM, Zhang XK, ''et al.'' |title=A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter. |journal=Mol. Endocrinol. |volume=4 |issue= 11 |pages= 1727-36 |year= 1991 |pmid= 2177841 |doi= }}
* {{cite journal | vauthors = Brand N, Petkovich M, Krust A, Chambon P, de Thé H, Marchio A, Tiollais P, Dejean A | title = Identification of a second human retinoic acid receptor | journal = Nature | volume = 332 | issue = 6167 | pages = 850–3 | date = Apr 1988 | pmid = 2833708 | doi = 10.1038/332850a0 }}
*{{cite journal | author=de Thé H, Marchio A, Tiollais P, Dejean A |title=A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma. |journal=Nature |volume=330 |issue= 6149 |pages= 667-70 |year= 1988 |pmid= 2825037 |doi= 10.1038/330667a0 }}
* {{cite journal | vauthors = Benbrook D, Lernhardt E, Pfahl M | title = A new retinoic acid receptor identified from a hepatocellular carcinoma | journal = Nature | volume = 333 | issue = 6174 | pages = 669–72 | date = Jun 1988 | pmid = 2836738 | doi = 10.1038/333669a0 }}
*{{cite journal | author=Brand N, Petkovich M, Krust A, ''et al.'' |title=Identification of a second human retinoic acid receptor. |journal=Nature |volume=332 |issue= 6167 |pages= 850-3 |year= 1988 |pmid= 2833708 |doi= 10.1038/332850a0 }}
* {{cite journal | vauthors = Dejean A, Bougueleret L, Grzeschik KH, Tiollais P | title = Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma | journal = Nature | volume = 322 | issue = 6074 | pages = 70–2 | year = 1986 | pmid = 3014347 | doi = 10.1038/322070a0 }}
*{{cite journal | author=Benbrook D, Lernhardt E, Pfahl M |title=A new retinoic acid receptor identified from a hepatocellular carcinoma. |journal=Nature |volume=333 |issue= 6174 |pages= 669-72 |year= 1988 |pmid= 2836738 |doi= 10.1038/333669a0 }}
* {{cite journal | vauthors = Si SP, Tsou HC, Lee X, Peacocke M | title = Effect of cellular senescence and retinoic acid on the expression of cellular retinoic acid binding proteins in skin fibroblasts | journal = Experimental Cell Research | volume = 219 | issue = 1 | pages = 243–8 | date = Jul 1995 | pmid = 7628539 | doi = 10.1006/excr.1995.1224 }}
*{{cite journal | author=Mattei MG, de Thé H, Mattei JF, ''et al.'' |title=Assignment of the human hap retinoic acid receptor RAR beta gene to the p24 band of chromosome 3. |journal=Hum. Genet. |volume=80 |issue= 2 |pages= 189-90 |year= 1988 |pmid= 2844650 |doi=  }}
* {{cite journal | vauthors = Houle B, Pelletier M, Wu J, Goodyer C, Bradley WE | title = Fetal isoform of human retinoic acid receptor beta expressed in small cell lung cancer lines | journal = Cancer Research | volume = 54 | issue = 2 | pages = 365–9 | date = Jan 1994 | pmid = 8275470 | doi =  }}
*{{cite journal  | author=Dejean A, Bougueleret L, Grzeschik KH, Tiollais P |title=Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma. |journal=Nature |volume=322 |issue= 6074 |pages= 70-2 |year= 1986 |pmid= 3014347 |doi= 10.1038/322070a0 }}
* {{cite journal | vauthors = Knegtel RM, Katahira M, Schilthuis JG, Bonvin AM, Boelens R, Eib D, van der Saag PT, Kaptein R | title = The solution structure of the human retinoic acid receptor-beta DNA-binding domain | journal = Journal of Biomolecular NMR | volume = 3 | issue = 1 | pages = 1–17 | date = Jan 1993 | pmid = 8383553 | doi = 10.1007/BF00242472 }}
*{{cite journal | author=Si SP, Tsou HC, Lee X, Peacocke M |title=Effect of cellular senescence and retinoic acid on the expression of cellular retinoic acid binding proteins in skin fibroblasts. |journal=Exp. Cell Res. |volume=219 |issue= 1 |pages= 243-8 |year= 1995 |pmid= 7628539 |doi= 10.1006/excr.1995.1224 }}
*{{cite journal | author=Houle B, Pelletier M, Wu J, ''et al.'' |title=Fetal isoform of human retinoic acid receptor beta expressed in small cell lung cancer lines. |journal=Cancer Res. |volume=54 |issue= 2 |pages= 365-9 |year= 1994 |pmid= 8275470 |doi=  }}
*{{cite journal | author=Knegtel RM, Katahira M, Schilthuis JG, ''et al.'' |title=The solution structure of the human retinoic acid receptor-beta DNA-binding domain. |journal=J. Biomol. NMR |volume=3 |issue= 1 |pages= 1-17 |year= 1993 |pmid= 8383553 |doi= }}
}}
{{refend}}
{{refend}}


{{NLM content}}
{{NLM content}}
{{protein-stub}}
{{gene-3-stub}}
{{Transcription factors}}
{{PDB Gallery|geneid=5915}}
{{Transcription factors|g2}}
{{Retinoid receptor modulators}}
 
[[Category:Intracellular receptors]]
[[Category:Intracellular receptors]]
[[Category:Transcription factors]]
[[Category:Transcription factors]]

Revision as of 15:39, 23 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

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n/a

RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Retinoic acid receptor beta (RAR-beta), also known as NR1B2 (nuclear receptor subfamily 1, group B, member 2) is a nuclear receptor that in humans is encoded by the RARB gene.[1][2]

Function

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.[1]

Interactions

Retinoic acid receptor beta has been shown to interact with NR4A2.[3]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: RARB retinoic acid receptor, beta".
  2. ↑ Mattei MG, de Thé H, Mattei JF, Marchio A, Tiollais P, Dejean A (Oct 1988). "Assignment of the human hap retinoic acid receptor RAR beta gene to the p24 band of chromosome 3". Human Genetics. 80 (2): 189–90. doi:10.1007/BF00702867. PMID 2844650.
  3. ↑ Perlmann T, Jansson L (Apr 1995). "A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1". Genes & Development. 9 (7): 769–82. doi:10.1101/gad.9.7.769. PMID 7705655.

Further reading

  • Dejean A, de Thé H (Jun 1990). "Hepatitis B virus as an insertional mutagene in a human hepatocellular carcinoma". Molecular Biology & Medicine. 7 (3): 213–22. PMID 2170809.
  • Sun SY (Jan 2004). "Retinoic acid receptor beta and colon cancer". Cancer Biology & Therapy. 3 (1): 87–8. doi:10.4161/cbt.3.1.686. PMID 14726690.
  • Saba N, Jain S, Khuri F (2004). "Chemoprevention in lung cancer". Current Problems in Cancer. 28 (5): 287–306. doi:10.1016/j.currproblcancer.2004.05.005. PMID 15375805.
  • Klein O, Grignon Y, Civit T, Auque J, Marchal JC (Sep 2005). "[Methylation status of RARbeta gene promoter in low and high grade cerebral glioma. Comparison with normal tissue. Immuno-histochemical study of nuclear RARbeta expression in low and high grade cerebral glioma cells. Comparison with normal cells. 48 tumors]". Neuro-Chirurgie. 51 (3-4 Pt 1): 147–54. PMID 16389900.
  • Katahira M, Knegtel RM, Boelens R, Eib D, Schilthuis JG, van der Saag PT, Kaptein R (Jul 1992). "Homo- and heteronuclear NMR studies of the human retinoic acid receptor beta DNA-binding domain: sequential assignments and identification of secondary structure elements". Biochemistry. 31 (28): 6474–80. doi:10.1021/bi00143a017. PMID 1321662.
  • Berrodin TJ, Marks MS, Ozato K, Linney E, Lazar MA (Sep 1992). "Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein". Molecular Endocrinology. 6 (9): 1468–78. doi:10.1210/me.6.9.1468. PMID 1331778.
  • van der Leede BJ, Folkers GE, Kruyt FA, van der Saag PT (Oct 1992). "Genomic organization of the human retinoic acid receptor beta 2". Biochemical and Biophysical Research Communications. 188 (2): 695–702. doi:10.1016/0006-291X(92)91112-4. PMID 1332705.
  • Prentice A, Matthews CJ, Thomas EJ, Redfern CP (May 1992). "The expression of retinoic acid receptors in cultured human endometrial stromal cells and effects of retinoic acid". Human Reproduction. 7 (5): 692–700. doi:10.1093/oxfordjournals.humrep.a137721. PMID 1379266.
  • Shen S, Kruyt FA, den Hertog J, van der Saag PT, Kruijer W (1992). "Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsiveness". DNA Sequence. 2 (2): 111–9. doi:10.3109/10425179109039679. PMID 1663808.
  • de Thé H, Vivanco-Ruiz MM, Tiollais P, Stunnenberg H, Dejean A (Jan 1990). "Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene". Nature. 343 (6254): 177–80. doi:10.1038/343177a0. PMID 2153268.
  • Hoffmann B, Lehmann JM, Zhang XK, Hermann T, Husmann M, Graupner G, Pfahl M (Nov 1990). "A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter". Molecular Endocrinology. 4 (11): 1727–36. doi:10.1210/mend-4-11-1727. PMID 2177841.
  • de Thé H, Marchio A, Tiollais P, Dejean A (1988). "A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma". Nature. 330 (6149): 667–70. doi:10.1038/330667a0. PMID 2825037.
  • Brand N, Petkovich M, Krust A, Chambon P, de Thé H, Marchio A, Tiollais P, Dejean A (Apr 1988). "Identification of a second human retinoic acid receptor". Nature. 332 (6167): 850–3. doi:10.1038/332850a0. PMID 2833708.
  • Benbrook D, Lernhardt E, Pfahl M (Jun 1988). "A new retinoic acid receptor identified from a hepatocellular carcinoma". Nature. 333 (6174): 669–72. doi:10.1038/333669a0. PMID 2836738.
  • Dejean A, Bougueleret L, Grzeschik KH, Tiollais P (1986). "Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma". Nature. 322 (6074): 70–2. doi:10.1038/322070a0. PMID 3014347.
  • Si SP, Tsou HC, Lee X, Peacocke M (Jul 1995). "Effect of cellular senescence and retinoic acid on the expression of cellular retinoic acid binding proteins in skin fibroblasts". Experimental Cell Research. 219 (1): 243–8. doi:10.1006/excr.1995.1224. PMID 7628539.
  • Houle B, Pelletier M, Wu J, Goodyer C, Bradley WE (Jan 1994). "Fetal isoform of human retinoic acid receptor beta expressed in small cell lung cancer lines". Cancer Research. 54 (2): 365–9. PMID 8275470.
  • Knegtel RM, Katahira M, Schilthuis JG, Bonvin AM, Boelens R, Eib D, van der Saag PT, Kaptein R (Jan 1993). "The solution structure of the human retinoic acid receptor-beta DNA-binding domain". Journal of Biomolecular NMR. 3 (1): 1–17. doi:10.1007/BF00242472. PMID 8383553.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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