Reticulum cell sarcoma

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Reticulum cell sarcoma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Reticulum Cell Sarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

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Physical Examination

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords:Histiocytic lymphoma, histiocytic lymphosarcoma

Overview

A malignant tumor of reticular tissue in the bone that is composed primarily of neoplastic histocytes.

Pathophysiology

The dominant cell type is thought to be derived from histiocytes or macrophages. More recent thinking indicates that this cancer may arise from lymphocytes or immunoblasts.

Differentiating Reticulum Cell Sarcoma From Other Diseases

Reticulum cell sarcoma should be distinguished from the following diseases:

Epidemiology and Demographics

  • Presents in middle age

Diagnosis

Symptoms

  • Localized bone pain and tenderness

Physical Examination

  • Tenderness of bone
  • Effusion of adjacent joint

Imaging Findings

  • Osteolytic lesions with minimal periosteal reactions are present on plain films of the bone

Pathology

Treatment

Early stage I tumors

Advanced Tumors

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